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Chirp stimulus responses in a morphologically realistic model (Narayanan and Johnston, 2007)
 
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Model Information
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Accession:
147578
...we built a multicompartmental model with a morphologically realistic three-dimensional reconstruction of a CA1 pyramidal neuron. The only active conductance we added to the model was the h conductance. ... We conclude that experimentally observed gradient in density of h channels could theoretically account for experimentally observed gradient in resonance properties (Narayanan and Johnston, 2007).
Reference:
1 .
Narayanan R, Johnston D (2007) Long-term potentiation in rat hippocampal neurons is accompanied by spatially widespread changes in intrinsic oscillatory dynamics and excitability.
Neuron
56
:1061-75
[
PubMed
]
Model Information
(Click on a link to find other models with that property)
Model Type:
Neuron or other electrically excitable cell;
Dendrite;
Brain Region(s)/Organism:
Hippocampus;
Cell Type(s):
Hippocampus CA1 pyramidal GLU cell;
Channel(s):
I h;
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment:
NEURON;
Model Concept(s):
Ion Channel Kinetics;
Active Dendrites;
Detailed Neuronal Models;
Implementer(s):
Narayanan, Rishikesh [rishi at iisc.ac.in];
Search NeuronDB
for information about:
Hippocampus CA1 pyramidal GLU cell
;
I h
;
/
MultiChirp
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