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Network bursts in cultured NN result from different adaptive mechanisms (Masquelier & Deco 2013)
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It is now well established that cultured neuron networks are spontaneously active, and tend to synchronize. Synchronous events typically involve the whole network, and have thus been termed “network spikes” (NS). Using experimental recordings and numerical simulations, we show here that the inter-NS interval statistics are complex, and allow inferring the neural mechanisms at work, in particular the adaptive ones, and estimating a number of parameters to which we cannot access experimentally.
Masquelier T, Deco G (2013) Network bursting dynamics in excitatory cortical neuron cultures results from the combination of different adaptive mechanisms.
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Cochlear nucleus pyramidal/fusiform GLU cell;
Abstract integrate-and-fire adaptive exponential (AdEx) neuron;
Temporal Pattern Generation;
Short-term Synaptic Plasticity;
Spike Frequency Adaptation;
Masquelier, Tim [timothee.masquelier at alum.mit.edu];
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Cochlear nucleus pyramidal/fusiform GLU cell
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