ModelDB: Calcium waves and mGluR-dependent synaptic plasticity in CA1 pyr. neurons (Ashhad & Narayanan 2013)

Accession:150551

A morphologically realistic, conductance-based model equipped with kinetic schemes that govern several calcium signalling modules and pathways in CA1 pyramidal neurons
Reference:
1 . Ashhad S, Narayanan R (2013) Quantitative interactions between the A-type K+ current and inositol trisphosphate receptors regulate intraneuronal Ca2+ waves and synaptic plasticity. J Physiol 591:1645-69 [PubMed]

Model Information (Click on a link to find other models with that property)

Model Type:	Neuron or other electrically excitable cell; Synapse; Channel/Receptor; Dendrite;
Brain Region(s)/Organism:	Hippocampus;
Cell Type(s):	Hippocampus CA1 pyramidal GLU cell;
Channel(s):	I Na,t; I L high threshold; I T low threshold; I A; I K; Ca pump;
Gap Junctions:
Receptor(s):	AMPA; NMDA; mGluR; IP3;
Gene(s):
Transmitter(s):	Glutamate;
Simulation Environment:	NEURON;
Model Concept(s):	Active Dendrites; Synaptic Plasticity; Signaling pathways; Calcium dynamics; G-protein coupled; Calcium waves;
Implementer(s):	Narayanan, Rishikesh [rishi at iisc.ac.in]; Ashhad, Sufyan [soofy at mbu.iisc.ernet.in];

Search NeuronDB for information about: Hippocampus CA1 pyramidal GLU cell; AMPA; NMDA; mGluR; IP3; I Na,t; I L high threshold; I T low threshold; I A; I K; Ca pump; Glutamate;