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A model of local field potentials generated by medial superior olive neurons (Goldwyn et al 2014)
 
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Model Information
Model File
Citations
Accession:
152112
A computational model of local field potentials generated by medial superior olive neurons. These field potentials are known as the "auditory neurophonic". MSO neuron is modeled as a soma and two dendrites (following Mathews et al, Nature Neurosci, 2010). Intracellular and a 1D extracellular domain are dynamically coupled and solved to simulate spatial-temporal patterns of membrane voltage and extracellular voltage in response to trains of synaptic inputs (monolateral or bilateral, excitation and/or inhibition). The model produces spatio-temporal patterns similar to neurophonic responses recorded in vivo, as discussed in the accompanying manuscript.
Reference:
1 .
Goldwyn JH, Mc Laughlin M, Verschooten E, Joris PX, Rinzel J (2014) A model of the medial superior olive explains spatiotemporal features of local field potentials.
J Neurosci
34
:11705-22
[
PubMed
]
Model Information
(Click on a link to find other models with that property)
Model Type:
Neuron or other electrically excitable cell;
Brain Region(s)/Organism:
Cell Type(s):
Medial Superior Olive (MSO) cell;
Channel(s):
I h;
I_KLT;
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment:
MATLAB;
Model Concept(s):
Evoked LFP;
Implementer(s):
Goldwyn, Joshua [jhgoldwyn at gmail.com];
Search NeuronDB
for information about:
I h
;
I_KLT
;
/
GoldwynEtAl2014
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