"... Here we demonstrate
that biophysical models of channel noise can give rise to two kinds of
recently discovered stochastic facilitation effects in a
Hodgkin-Huxley-like model of auditory brainstem neurons. The first,
known as slope-based stochastic resonance (SBSR), enables phasic
neurons to emit action potentials that can encode the slope of inputs
that vary slowly relative to key time constants in the model. The
second, known as inverse stochastic resonance (ISR), occurs in
tonically firing neurons when small levels of noise inhibit tonic
firing and replace it with burstlike dynamics.
... our results show that possible
associated computational benefits may occur due to channel noise in
neurons of the auditory brainstem.
Caplan JS, Williams AH, Marder E (2014) Many parameter sets in a multicompartment model oscillator are robust to temperature perturbations. J Neurosci 34:4963-75 [PubMed]