"...
Experimental
observations have shown ... that fast-activating
voltage- and calcium-dependent potassium (BK) current
tends to promote bursting in pituitary cells.
This burst promoting
effect requires fast activation of the BK current,
otherwise it is inhibitory to bursting. In this work, we analyze
a pituitary cell model in order to answer the question
of why the BK activation must be fast to promote bursting.
..."
Reference:
1 .
Vo T, Tabak J, Bertram R, Wechselberger M (2014) A geometric understanding of how fast activating potassium channels promote bursting in pituitary cells. J Comput Neurosci 36:259-78 [PubMed]
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