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Microcircuits of L5 thick tufted pyramidal cells (Hay & Segev 2015)
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"... We simulated detailed conductance-based models of TTCs (Layer 5 thick tufted pyramidal cells) forming recurrent microcircuits that were interconnected as found experimentally; the network was embedded in a realistic background synaptic activity. ... Our findings indicate that dendritic nonlinearities are pivotal in controlling the gain and the computational functions of TTCs microcircuits, which serve as a dominant output source for the neocortex. "
Hay E, Segev I (2015) Dendritic Excitability and Gain Control in Recurrent Cortical Microcircuits.
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Neocortex L5/6 pyramidal GLU cell;
I L high threshold;
I T low threshold;
I A, slow;
Dendritic Action Potentials;
Detailed Neuronal Models;
Hay, Etay [etay.hay at mail.huji.ac.il];
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Neocortex L5/6 pyramidal GLU cell
I L high threshold
I T low threshold
I A, slow
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