Find models by
Find models for
Find models of
Electrical synapses (gap junctions)
SenseLab mailing list
ModelDB related resources
Computational neuroscience ecosystem
Models in a git repository
Cerebellar purkinje cell: K and Ca channels regulate APs (Miyasho et al 2001)
Download zip file
Help downloading and running models
Versions on GitHub
We adopted De Schutter and Bower's model as the starting point, then modified the descriptions of several ion channels, such as the P-type Ca channel and the delayed rectifier K channel, and added class-E Ca channels and D-type K channels to the model. Our new model reproduces most of our experimental results and supports the conclusions of our experimental study that class-E Ca channels and D-type K channels are present and functioning in the dendrites of Purkinje neurons.
Miyasho T, Takagi H, Suzuki H, Watanabe S, Inoue M, Kudo Y, Miyakawa H (2001) Low-threshold potassium channels and a low-threshold calcium channel regulate Ca2+ spike firing in the dendrites of cerebellar Purkinje neurons: a modeling study.
(Click on a link to find other models with that property)
Neuron or other electrically excitable cell;
Cerebellum Purkinje GABA cell;
I T low threshold;
I A, slow;
Action Potential Initiation;
Dendritic Action Potentials;
Influence of Dendritic Geometry;
Detailed Neuronal Models;
Miyakawa, H [Miyakawa at ls.toyaku.ac.jp];
for information about:
Cerebellum Purkinje GABA cell
I T low threshold
I A, slow
File not selected
<- Select file from this column.
Load Model View
Loading data, please wait...