Striatal Spiny Projection Neuron (SPN) plasticity rule (Jedrzejewska-Szmek et al 2016)

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Accession:189153

Reference:
1 . Jedrzejewska-Szmek J, Damodaran S, Dorman DB, Blackwell KT (2017) Calcium dynamics predict direction of synaptic plasticity in striatal spiny projection neurons. Eur J Neurosci 45:1044-1056 [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type: Dendrite;
Brain Region(s)/Organism:
Cell Type(s):
Channel(s):
Gap Junctions:
Receptor(s): AMPA; NMDA; GabaA;
Gene(s):
Transmitter(s): Glutamate;
Simulation Environment: GENESIS;
Model Concept(s): Calcium dynamics; Synaptic Plasticity;
Implementer(s): Jedrzejewska-Szmek, Joanna ; Damodaran, Sriraman ; Dorman, Daniel B ; Blackwell, Avrama [avrama at gmu.edu];
Search NeuronDB for information about:  GabaA; AMPA; NMDA; Glutamate;
//genesis 
//P_K.g

//Pre-synaptic parameters
str prestim = 2
float pulseFreq = 50
int pulses = 1

//Post-synaptic parameters
float inject=1e-9 //1e-9
float burstFreq = 1 
int numbursts = 1
float trainFreq= 0.1
int numtrains = 10

AP_durtime=0.005 
float APinterval={1.0/50.0}
int numAP=3
if ({Timing}=="Pre")
	float ISI = 0.010
elif ({Timing}=="Post")
	float ISI =-0.030
end


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