Conditions of dominant effectiveness of distal dendrites (Korogod, Kulagina 1998)

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Accession:19366
The model illustrates and explains bistable spatial patterns of the current transfer effectiveness in the active dendrite with distributed (multiple) tonic excitatory, NMDA type, synaptic input.
Reference:
1 . Korogod SM, Kulagina IB (1998) Conditions of dominant effectiveness of distal sites of active uniform dendrites with distributed tonic inputs. Neurophysiology 30:310-315
Model Information (Click on a link to find other models with that property)
Model Type: Neuron or other electrically excitable cell;
Brain Region(s)/Organism:
Cell Type(s):
Channel(s):
Gap Junctions:
Receptor(s): NMDA;
Gene(s):
Transmitter(s):
Simulation Environment: NEURON;
Model Concept(s): Simplified Models; Active Dendrites;
Implementer(s): Korogod, Sergey M [Korogod at ff.dsu.dp.ua]; Kulagina, Irina B [Kulagina at ff.dsu.dp.ua]; Kukushka, Valery I [Valery at ff.dsu.dp.ua];
Search NeuronDB for information about:  NMDA;
// Conditions of Dominat Effectiveness of Distal Sites of Active Uniform Dendrites with Distributed Tonic Inputs
// S.M. Korogod, I.B. Kulagina
// Neirofiziologiya/Neurophysiology, Vol.30, Nos.4/5, pp.376-382, July-October, 1998

objectvar VRGraph

// make graphics for Fig.2. A
proc MakeVRGraph() {
  strdef OutLine
  VRGraph = new Graph(0)
  VRGraph.xaxis()
  VRGraph.yaxis()
  RRGraph = new RangeVarPlot("v")
  OutLine = "Axon RRGraph.begin(0) Dendrite RRGraph.end(1)"
  execute1(OutLine)
  VRGraph.addobject(RRGraph, 1, 1, 1, 1)
  VRGraph.size(-200, 800, -70, 0)
  VRGraph.view(-200, -75, 1000, 75, 350, 300, 300.0, 250)
  VRGraph.label(0.5, 1, "A", 2, 1, 0, 1, 1)
  VRGraph.label(0.05, 1, "mV", 2, 1, 0, 1, 1)
  VRGraph.label(0.9, 0.21, "um", 2, 1, 0, 1, 1)
  VRGraph.label(0.9, 0.85, "E", 2, 1, 0, 1, 1)
  VRGraph.yaxis(3)
  VRGraph.xaxis(-200, 800, -70, 10, 0, 0, 1)
  VRGraph.yaxis(-70, 0, -200, 7, 0, 0, 1)
  flush_list.append(VRGraph)
  VRGraph.save_name("flush_list.")
  objectvar RRGraph
} // MakeVRGraph()

proc Destroy() {
  VRGraph.unmap()
} // Destroy()

proc MainExec() {
  GetModelTopology()
  OutLine = "access Soma"
  execute1(OutLine)
  OutLine = "Dendrite.gnmdabar_nmda = 0.0061"
  execute1(OutLine)
  tstop = 400
  MakeVRGraph()
} // MainExec()

MainExec()

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