Conditions of dominant effectiveness of distal dendrites (Korogod, Kulagina 1998)

 Download zip file 
Help downloading and running models
Accession:19366
The model illustrates and explains bistable spatial patterns of the current transfer effectiveness in the active dendrite with distributed (multiple) tonic excitatory, NMDA type, synaptic input.
Reference:
1 . Korogod SM, Kulagina IB (1998) Conditions of dominant effectiveness of distal sites of active uniform dendrites with distributed tonic inputs. Neurophysiology 30:310-315
Model Information (Click on a link to find other models with that property)
Model Type: Neuron or other electrically excitable cell;
Brain Region(s)/Organism:
Cell Type(s):
Channel(s):
Gap Junctions:
Receptor(s): NMDA;
Gene(s):
Transmitter(s):
Simulation Environment: NEURON;
Model Concept(s): Simplified Models; Active Dendrites;
Implementer(s): Korogod, Sergey M [Korogod at ff.dsu.dp.ua]; Kulagina, Irina B [Kulagina at ff.dsu.dp.ua]; Kukushka, Valery I [Valery at ff.dsu.dp.ua];
Search NeuronDB for information about:  NMDA;
TITLE passive membrane channel

COMMENT
A replica of NEURON pas.mod membrane mechanism 
for passive soma and axon with the parameters as in the models 
described in: 
Korogod SM and Kulagina IB (1998) Biol Cybern 79:231-240
and
Korogod SM and Kulagina IB (1998) Neirofiziologia/Neurophysiology 30(4/5):376-382
Kluver Academic/ Plenum Publishers English version:
Korogod SM and Kulagina IB (1999) Neurophysiology 30(4/5):310-315
ENDCOMMENT

UNITS {
   (mV) = (millivolt)
   (mA) = (milliamp)
}

INDEPENDENT { v FROM -100 TO 50 WITH 50   (mV) }

NEURON {
   SUFFIX PasSA
   NONSPECIFIC_CURRENT i
   RANGE g, erev
}

PARAMETER {
   g = .000677254 (mho/cm2)
   erev = -65     (mV)
}

ASSIGNED { i (mA/cm2) }

BREAKPOINT {
   i = g*(v - erev)
}

Loading data, please wait...