Borderline Personality Disorder (Berdahl, 2010)

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Accession:195886
This research developed a neural network simulation constrained by known neuroanatomy and neurophysiology to generate ideas about the etiology of Borderline Personality Disorder. The simulations suggest an important role for the amygdala-ventromedial prefrontal cortex-amygdala circuit.
Reference:
1 . Berdahl CH (2010) A neural network model of Borderline Personality Disorder. Neural Netw 23:177-88 [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type:
Brain Region(s)/Organism: Amygdala; Prefrontal cortex (PFC); Brainstem;
Cell Type(s):
Channel(s):
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment: C or C++ program;
Model Concept(s): Long-term Synaptic Plasticity; Borderline Personality Disorder (BPD);
Implementer(s): Berdahl, Carl H [Carl.Berdahl at verizon.net];
// vmPFCDlg.cpp : implementation file
//

#include "stdafx.h"
#include "BPDBrain.h"
#include "vmPFCDlg.h"

#ifdef _DEBUG
#define new DEBUG_NEW
#undef THIS_FILE
static char THIS_FILE[] = __FILE__;
#endif

/////////////////////////////////////////////////////////////////////////////
// CvmPFCDlg dialog


CvmPFCDlg::CvmPFCDlg(CWnd* pParent /*=NULL*/)
	: CDialog(CvmPFCDlg::IDD, pParent)
{
	//{{AFX_DATA_INIT(CvmPFCDlg)
	m_B_VMPFC_EDIT = 3.0;
	m_C_VMPFC_EDIT = 0.5;
	m_I_VMPFC_EDIT = 0.5;
	m_A_VMPFC_EDIT = 0.7;
	m_Zo_VMPFC_EDIT = 1.0;
	//}}AFX_DATA_INIT
}


void CvmPFCDlg::DoDataExchange(CDataExchange* pDX)
{
	CDialog::DoDataExchange(pDX);
	//{{AFX_DATA_MAP(CvmPFCDlg)
	DDX_Text(pDX, IDC_B_VMPFC_EDIT, m_B_VMPFC_EDIT);
	DDX_Text(pDX, IDC_C_VMPFC_EDIT, m_C_VMPFC_EDIT);
	DDX_Text(pDX, IDC_I_VMPFC_EDIT, m_I_VMPFC_EDIT);
	DDX_Text(pDX, IDC_A_VMPFC_EDIT, m_A_VMPFC_EDIT);
	DDX_Text(pDX, IDC_Z_VMPFC_O_EDIT, m_Zo_VMPFC_EDIT);
	//}}AFX_DATA_MAP
}


BEGIN_MESSAGE_MAP(CvmPFCDlg, CDialog)
	//{{AFX_MSG_MAP(CvmPFCDlg)
		// NOTE: the ClassWizard will add message map macros here
	//}}AFX_MSG_MAP
END_MESSAGE_MAP()

/////////////////////////////////////////////////////////////////////////////
// CvmPFCDlg message handlers

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