A multilayer cortical model to study seizure propagation across microdomains (Basu et al. 2015)

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Accession:206238
A realistic neural network was used to simulate a region of neocortex to obtain extracellular LFPs from ‘virtual micro-electrodes’ and produce test data for comparison with multisite microelectrode recordings. A model was implemented in the GENESIS neurosimulator. A simulated region of cortex was represented by layers 2/3, 5/6 (interneurons and pyramidal cells) and layer 4 stelate cells, spaced at 25 µm in each horizontal direction. Pyramidal cells received AMPA and NMDA inputs from neighboring cells at the basal and apical dendrites. The LFP data was generated by simulating 16-site electrode array with the help of ‘efield’ objects arranged at the predetermined positions with respect to the surface of the simulated network. The LFP for the model is derived from a weighted average of the current sources summed over all cellular compartments. Cell models were taken from from Traub et al. (2005) J Neurophysiol 93(4):2194-232.
References:
1 . Basu I, Kudela P, Korzeniewska A, Franaszczuk PJ, Anderson WS (2015) A study of the dynamics of seizure propagation across micro domains in the vicinity of the seizure onset zone. J Neural Eng 12:046016 [PubMed]
2 . Basu I, Kudela P, Anderson WS (2014) Determination of seizure propagation across microdomains using spectral measures of causality. Conf Proc IEEE Eng Med Biol Soc 2014:6349-52 [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type: Realistic Network;
Brain Region(s)/Organism: Neocortex;
Cell Type(s): Neocortex U1 L2/6 pyramidal intratelencephalic GLU cell; Neocortex U1 L5B pyramidal pyramidal tract GLU cell; Thalamus reticular nucleus GABA cell; Neocortex spiking low threshold (LTS) neuron; Neocortex spiking regular (RS) neuron; Neocortex layer 2-3 interneuron; Neocortex layer 5 interneuron;
Channel(s): I Na,p; I Na,t; I K; I A; I M; I h; I K,Ca; I A, slow; I L high threshold; I T low threshold; I Calcium;
Gap Junctions: Gap junctions;
Receptor(s): AMPA; GabaA; NMDA;
Gene(s):
Transmitter(s): Glutamate; Gaba; Amino Acids;
Simulation Environment: GENESIS;
Model Concept(s): Activity Patterns; Epilepsy;
Implementer(s): Anderson, WS ; Kudela, Pawel ;
Search NeuronDB for information about:  Thalamus reticular nucleus GABA cell; Neocortex U1 L5B pyramidal pyramidal tract GLU cell; Neocortex U1 L2/6 pyramidal intratelencephalic GLU cell; GabaA; AMPA; NMDA; I Na,p; I Na,t; I L high threshold; I T low threshold; I A; I K; I M; I h; I K,Ca; I Calcium; I A, slow; Amino Acids; Gaba; Glutamate;
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BasuEtAl2015
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ModelDescription.pdf
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P6RSd_P6RSc.g
P6RSd_P6RSd.g
P6RSd_P6RSd_Gap.g
P6RSd_raninput.g
P6RSd_ST4RS.g
P6RSd_synapsedefs.g
P6RSd_TCR.g
P6RSdcell3Dpk.p
P6RSdchanpk.g
P6RSdprotodefs.g
P6RSsyncond.g
pgenesis_command
protodefs.g
protospikeB23FS.g
protospikeB5FS.g
protospikeC23FS.g
protospikeC5FS.g
protospikeI23LTS.g
protospikeI5LTS.g
protospikenRT.g
protospikeP23FRBa.g
protospikeP23RSa.g
protospikeP23RSb.g
protospikeP23RSc.g
protospikeP23RSd.g
protospikeP5IBa.g
protospikeP5IBb.g
protospikeP5IBc.g
protospikeP5IBd.g
protospikeP5RSa.g
protospikeP6RSa.g
protospikeP6RSb.g
protospikeP6RSc.g
protospikeP6RSd.g
protospikeST4RS.g
protospikeTCR.g
randominputdefs.g
spikedefs.g
ST4RS.g
ST4RS_B23FS.g
ST4RS_B5FS.g
ST4RS_C23FS.g
ST4RS_C5FS.g
ST4RS_I23LTS.g
ST4RS_I5LTS.g
ST4RS_P23FRBa.g
ST4RS_P23RSa.g
ST4RS_P23RSb.g
ST4RS_P23RSc.g
ST4RS_P23RSd.g
ST4RS_P5IBa.g
ST4RS_P5IBb.g
ST4RS_P5IBc.g
ST4RS_P5IBd.g
ST4RS_P5RSa.g
ST4RS_P6RSa.g
ST4RS_P6RSb.g
ST4RS_P6RSc.g
ST4RS_P6RSd.g
ST4RS_raninput.g
ST4RS_ST4RS.g
ST4RS_ST4RS_Gap.g
ST4RS_synapsedefs.g
ST4RScell3Dpk.p
ST4RSchanpk.g
ST4RSprotodefs.g
ST4RSsyncond.g
synapticdelays.g *
synapticprobsTraub.g
synchansB23FS.g *
synchansB5FS.g *
synchansC23FS.g *
synchansC5FS.g *
synchansI23LTS.g *
synchansI5LTS.g *
synchansnRT.g *
synchansP23FRBa.g *
synchansP23RSa.g *
synchansP23RSb.g *
synchansP23RSc.g *
synchansP23RSd.g *
synchansP5IBa.g *
synchansP5IBb.g *
synchansP5IBc.g *
synchansP5IBd.g *
synchansP5RSa.g *
synchansP6RSa.g *
synchansP6RSb.g *
synchansP6RSc.g *
synchansP6RSd.g *
synchansSPIKEs.g *
synchansSPIKEs_base.g
synchansST4RS.g
synchansTCR.g *
syncond.g
syncond2.g
TCR.g
TCR_B23FS.g
TCR_B5FS.g
TCR_C23FS.g
TCR_C5FS.g
TCR_nRT.g
TCR_P23FRBa.g
TCR_P23RSa.g
TCR_P23RSb.g
TCR_P23RSc.g
TCR_P23RSd.g
TCR_P5IBa.g
TCR_P5IBb.g
TCR_P5IBc.g
TCR_P5IBd.g
TCR_P5RSa.g
TCR_P6RSa.g
TCR_P6RSb.g
TCR_P6RSc.g
TCR_P6RSd.g
TCR_raninput.g
TCR_ST4RS.g
TCR_synapsedefs.g
TCRcellpk.p
TCRchanpk.g
TCRprotodefs.g
TCRsyncond.g
                            
//P23RS

float CondmaxP23RSAMPA_P23RS=600e-9 // base is 0.25e-9 (X 2.0 for most runs) Traub 2005

float CondmaxP23RSNMDA_P23RS=0.0625e-9 // base is 0.025e-9 (X 2.5 for most runs) Traub 2005

float CondmaxB23FSGABAa_P23RS=1.2e-9 // base is 1.2e-9 Traub 2005

float CondmaxP5IBAMPA_P23RS=1.0e-9 // base is 0.5e-9 (X 2.0 for most runs) Traub 2005

float CondmaxP5IBNMDA_P23RS=0.125e-9 // base is 0.05e-9 (X 2.5 for most runs) Traub 2005

float CondmaxP6RSAMPA_P23RS=1.00e-9 // base is 0.50e-9 (X 2.0 for most runs) Traub 2005

float CondmaxP6RSNMDA_P23RS=0.125e-9 // base is 0.05e-9 (X 2.5 for most runs) Traub 2005

float CondmaxC23FSGABAa_P23RS=1.2e-9 // base is 1.2e-9 Traub 2005

float CondmaxC5FSGABAa_P23RS=1.0e-9 // base is 1.0e-9 Traub 2005

float CondmaxST4RSAMPA_P23RS=2.00e-9 // base is 1.00e-9 (X 2.0 for most runs) Traub 2005

float CondmaxST4RSNMDA_P23RS=0.75e-9 // base is 0.10e-9 (X 2.5 for most runs) Traub 2005

float CondmaxI23LTSGABAa_P23RS=0.01e-9 // base is 0.01e-9 Traub 2005

float CondmaxI5LTSGABAa_P23RS=0.01e-9 // base is 0.01e-9 Traub 2005

float CondmaxTCRAMPA_P23RS=1.00e-9 // base is 0.50e-9 (X 2.0 for most runs) Traub 2005

float CondmaxTCRNMDA_P23RS=0.125e-9 // base is 0.05e-9 (X 2.5 for most runs) Traub 2005

float CondmaxP23FRBAMPA_P23RS=0.5e-9 // base is 0.25e-9 (X 2.0 for most runs) Traub 2005

float CondmaxP23FRBNMDA_P23RS=0.0625e-9 // base is 0.025e-9 (X 2.5 for most runs) Traub 2005

float CondmaxP5RSAMPA_P23RS=1.0e-9 // base is 0.5e-9 (X 2.0 for most runs) Traub 2005

float CondmaxP5RSNMDA_P23RS=0.125e-9 // base is 0.05e-9 (X 2.5 for most runs) Traub 2005

//B23FS

float CondmaxP23RSAMPA_B23FS=6.0e-9 // base is 3.0e-9 (X 2.0 for most runs) Traub 2005

float CondmaxP23RSNMDA_B23FS=0.03e-9 // base is 0.15e-9 (X 0.2 for most runs)  Traub 2005

float CondmaxB23FSGABAa_B23FS=0.2e-9 // base is 0.2e-9 Traub 2005

float CondmaxP5IBAMPA_B23FS=2.0e-9 // base is 1.0e-9 (X 2.0 for most runs) Traub 2005

float CondmaxP5IBNMDA_B23FS=0.03e-9 // base is 0.15e-9 (X 0.2 for most runs) Traub 2005

float CondmaxP6RSAMPA_B23FS=2.0e-9 // base is 1.0e-9 (X 2.0 for most runs) Traub 2005

float CondmaxP6RSNMDA_B23FS=0.02e-9 // base is 0.10e-9 (X 0.2 for most runs) Traub 2005

float CondmaxST4RSAMPA_B23FS=2.0e-9 // base is 1.0e-9 (X 2.0 for most runs) Traub 2005

float CondmaxST4RSNMDA_B23FS=0.03e-9 // base is 0.15e-9 (X 0.2 for most runs) Traub 2005

float CondmaxI23LTSGABAa_B23FS=0.01e-9 // base is 0.01e-9 Traub 2005

float CondmaxI5LTSGABAa_B23FS=0.01e-9 // base is 0.01e-9 Traub 2005

float CondmaxTCRAMPA_B23FS=0.2e-9 // base is 0.1e-9 (X 2.0 for most runs) Traub 2005

float CondmaxTCRNMDA_B23FS=0.002e-9 // base is 0.01e-9 (X 0.2 for most runs)  Traub 2005

float CondmaxP23FRBAMPA_B23FS=6.0e-9 // base is 3.0e-9 (X 2.0 for most runs) Traub 2005

float CondmaxP23FRBNMDA_B23FS=0.02e-9 // base is 0.10e-9 (X 0.2 for most runs)  Traub 2005

float CondmaxP5RSAMPA_B23FS=2.0e-9 // base is 1.0e-9 (X 2.0 for most runs) Traub 2005

float CondmaxP5RSNMDA_B23FS=0.03e-9 // base is 0.15e-9 (X 0.2 for most runs) Traub 2005

//P5IB

float CondmaxP23RSAMPA_P5IB=0.20e-9 // base is 0.10e-9 (X 2.0 for most runs) Traub 2005

float CondmaxP23RSNMDA_P5IB=0.025e-9 // base is 0.010e-9 (X 2.5 for most runs) Traub 2005

float CondmaxB5FSGABAa_P5IB=0.7e-9 // base is 0.7e-9 Traub 2005

float CondmaxP5IBAMPA_P5IB=4.00e-9 // base is 2.00e-9 (X 2.0 for most runs) Traub 2005

float CondmaxP5IBNMDA_P5IB=0.50e-9 // base is 0.20e-9 (X 2.5 for most runs)  Traub 2005

float CondmaxP6RSAMPA_P5IB=2.00e-9 // base is 1.00e-9 (X 2.0 for most runs) Traub 2005

float CondmaxP6RSNMDA_P5IB=0.25e-9 // base is 0.10e-9 (X 2.5 for most runs)  Traub 2005

float CondmaxC23FSGABAa_P5IB=1.0e-9 // base is 1.0e-9 Traub 2005

float CondmaxC5FSGABAa_P5IB=1.0e-9 // base is 1.0e-9 Traub 2005

float CondmaxST4RSAMPA_P5IB=2.00e-9 // base is 1.00e-9 (X 2.0 for most runs) Traub 2005

float CondmaxST4RSNMDA_P5IB=0.75e-9 // base is 0.10e-9 (X 2.5 for most runs)  Traub 2005

float CondmaxI23LTSGABAa_P5IB=0.02e-9 // base is 0.02e-9 Traub 2005

float CondmaxI5LTSGABAa_P5IB=0.05e-9 // base is 0.05e-9 Traub 2005

float CondmaxTCRAMPA_P5IB=3.00e-9 // base is 1.50e-9 (X 2.0 for most runs) Traub 2005

float CondmaxTCRNMDA_P5IB=0.375e-9 // base is 0.15e-9 (X 2.5 for most runs) Traub 2005

float CondmaxP23FRBAMPA_P5IB=0.20e-9 // base is 0.10e-9 (X 2.0 for most runs) Traub 2005

float CondmaxP23FRBNMDA_P5IB=0.025e-9 // base is 0.010e-9 (X 2.5 for most runs) Traub 2005

float CondmaxP5RSAMPA_P5IB=2.0e-9 // base is 1.0e-9 (X 2.0 for most runs) Traub 2005

float CondmaxP5RSNMDA_P5IB=0.25e-9 // base is 0.10e-9 (X 2.5 for most runs) Traub 2005

//B5FS

float CondmaxP23RSAMPA_B5FS=6.0e-9 // 2  base is 1.0e-9 (X 2.0 for most runs) Traub 2005

float CondmaxP23RSNMDA_B5FS=0.02e-9 // base is 0.1e-9 (X 0.2 for most runs)  Traub 2005

float CondmaxP5IBAMPA_B5FS=6.0e-9 // base is 3.0e-9 (X 2.0 for most runs) Traub 2005

float CondmaxP5IBNMDA_B5FS=0.03e-9 // base is 0.15e-9 (X 0.2 for most runs) Traub 2005

float CondmaxB5FSGABAa_B5FS=0.2e-9 // base is 0.2e-9 Traub 2005

float CondmaxP6RSAMPA_B5FS=6.0e-9 // base is 3.0e-9 (X 2.0 for most runs) Traub 2005

float CondmaxP6RSNMDA_B5FS=0.02e-9 // base is 0.10e-9 (X 0.2 for most runs) Traub 2005

float CondmaxST4RSAMPA_B5FS=2.0e-9 // base is 1.0e-9 (X 2.0 for most runs) Traub 2005

float CondmaxST4RSNMDA_B5FS=0.03e-9 // base is 0.15e-9 (X 0.2 for most runs) Traub 2005

float CondmaxI23LTSGABAa_B5FS=0.01e-9 // base is 0.01e-9 Traub 2005

float CondmaxI5LTSGABAa_B5FS=0.01e-9 // base is 0.01e-9 Traub 2005

float CondmaxTCRAMPA_B5FS=3.0e-9 // base is 1.5e-9 (X 2.0 for most runs) Traub 2005

float CondmaxTCRNMDA_B5FS=0.02e-9 // base is 0.10e-9 (X 0.2 for most runs)  Traub 2005

float CondmaxP23FRBAMPA_B5FS=2.0e-9 // base is 1.0e-9 (X 2.0 for most runs) Traub 2005

float CondmaxP23FRBNMDA_B5FS=0.02e-9 // base is 0.1e-9 (X 0.2 for most runs)  Traub 2005

float CondmaxP5RSAMPA_B5FS=6.0e-9 // base is 3.0e-9 (X 2.0 for most runs) Traub 2005

float CondmaxP5RSNMDA_B5FS=0.02e-9 // base is 0.1e-9 (X 0.2 for most runs) Traub 2005

//P6RS

float CondmaxP23RSAMPA_P6RS=1.00e-9 // base is 0.50e-9 (X 2.0 for most runs) Traub 2005

float CondmaxP23RSNMDA_P6RS=0.125e-9 // base is 0.050e-9 (X 2.5 for most runs) Traub 2005

float CondmaxB5FSGABAa_P6RS=0.70e-9 // base is 0.7e-9 Traub 2005

float CondmaxP5IBAMPA_P6RS=1.00e-9 // base is 2.00e-9 (X 2.0 for most runs) Traub 2005

float CondmaxP5IBNMDA_P6RS=0.50e-9 // base is 0.20e-9 (X 2.5 for most runs)  Traub 2005

float CondmaxP6RSAMPA_P6RS=2.00e-9 // base is 1.00e-9 (X 2.0 for most runs) Traub 2005

float CondmaxP6RSNMDA_P6RS=0.25e-9 // base is 0.10e-9 (X 2.5 for most runs)  Traub 2005

float CondmaxC23FSGABAa_P6RS=1.0e-9 // base is 1.0e-9 Traub 2005

float CondmaxC5FSGABAa_P6RS=1.0e-9 // base is 1.0e-9 Traub 2005

float CondmaxST4RSAMPA_P6RS=2.00e-9 // base is 1.00e-9 (X 2.0 for most runs) Traub 2005

float CondmaxST4RSNMDA_P6RS=0.75e-9 // base is 0.10e-9 (X 2.5 for most runs)  Traub 2005

float CondmaxI23LTSGABAa_P6RS=0.01e-9 // base is 0.01e-9 Traub 2005

float CondmaxI5LTSGABAa_P6RS=0.01e-9 // base is 0.01e-9 Traub 2005

float CondmaxTCRAMPA_P6RS=2.00e-9 // base is 1.00e-9 (X 2.0 for most runs) Traub 2005

float CondmaxTCRNMDA_P6RS=0.25e-9 // base is 0.10e-9 (X 2.5 for most runs) Traub 2005

float CondmaxP23FRBAMPA_P6RS=1.00e-9 // base is 0.50e-9 (X 2.0 for most runs) Traub 2005

float CondmaxP23FRBNMDA_P6RS=0.125e-9 // base is 0.050e-9 (X 2.5 for most runs) Traub 2005

float CondmaxP5RSAMPA_P6RS=2.0e-9 // base is 1.0e-9 (X 2.0 for most runs) Traub 2005

float CondmaxP5RSNMDA_P6RS=0.25e-9 // base is 0.10e-9 (X 2.5 for most runs) Traub 2005

//C23FS

float CondmaxP23RSAMPA_C23FS=6.0e-9 // base is 3.0e-9 (X 2.0 for most runs) Traub 2005

float CondmaxP23RSNMDA_C23FS=0.03e-9 // base is 0.15e-9 (X 0.2 for most runs)  Traub 2005

float CondmaxB23FSGABAa_C23FS=0.2e-9 // base is 0.2e-9 Traub 2005

float CondmaxP5IBAMPA_C23FS=2.0e-9 // base is 1.0e-9 (X 2.0 for most runs) Traub 2005

float CondmaxP5IBNMDA_C23FS=0.03e-9 // base is 0.15e-9 (X 0.2 for most runs) Traub 2005

float CondmaxP6RSAMPA_C23FS=2.0e-9 // base is 1.0e-9 (X 2.0 for most runs) Traub 2005

float CondmaxP6RSNMDA_C23FS=0.02e-9 // base is 0.10e-9 (X 0.2 for most runs) Traub 2005

float CondmaxST4RSAMPA_C23FS=2.0e-9 // base is 1.0e-9 (X 2.0 for most runs) Traub 2005

float CondmaxST4RSNMDA_C23FS=0.03e-9 // base is 0.15e-9 (X 0.2 for most runs) Traub 2005

float CondmaxI23LTSGABAa_C23FS=0.01e-9 // base is 0.01e-9 Traub 2005

float CondmaxI5LTSGABAa_C23FS=0.01e-9 // base is 0.01e-9 Traub 2005

float CondmaxTCRAMPA_C23FS=0.2e-9 // base is 0.1e-9 (X 2.0 for most runs) Traub 2005

float CondmaxTCRNMDA_C23FS=0.002e-9 // base is 0.01e-9 (X 0.2 for most runs)  Traub 2005

float CondmaxP23FRBAMPA_C23FS=6.0e-9 // base is 3.0e-9 (X 2.0 for most runs) Traub 2005

float CondmaxP23FRBNMDA_C23FS=0.02e-9 // base is 0.10e-9 (X 0.2 for most runs)  Traub 2005

float CondmaxP5RSAMPA_C23FS=2.0e-9 // base is 1.0e-9 (X 2.0 for most runs) Traub 2005

float CondmaxP5RSNMDA_C23FS=0.03e-9 // base is 0.15e-9 (X 0.2 for most runs) Traub 2005

//C5FS

float CondmaxP23RSAMPA_C5FS=2.0e-9 // base is 1.0e-9 (X 2.0 for most runs) Traub 2005

float CondmaxP23RSNMDA_C5FS=0.02e-9 // base is 0.10e-9 (X 0.2 for most runs)  Traub 2005

float CondmaxP5IBAMPA_C5FS=6.0e-9 // base is 3.0e-9 (X 2.0 for most runs) Traub 2005

float CondmaxP5IBNMDA_C5FS=0.03e-9 // base is 0.15e-9 (X 0.2 for most runs) Traub 2005

float CondmaxB5FSGABAa_C5FS=0.2e-9 // base is 0.2e-9 Traub 2005

float CondmaxP6RSAMPA_C5FS=6.0e-9 // base is 3.0e-9 (X 2.0 for most runs) Traub 2005

float CondmaxP6RSNMDA_C5FS=0.02e-9 // base is 0.10e-9 (X 0.2 for most runs) Traub 2005

float CondmaxST4RSAMPA_C5FS=2.0e-9 // base is 1.0e-9 (X 2.0 for most runs) Traub 2005

float CondmaxST4RSNMDA_C5FS=0.03e-9 // base is 0.15e-9 (X 0.2 for most runs) Traub 2005

float CondmaxI23LTSGABAa_C5FS=0.01e-9 // base is 0.01e-9 Traub 2005

float CondmaxI5LTSGABAa_C5FS=0.01e-9 // base is 0.01e-9 Traub 2005

float CondmaxTCRAMPA_C5FS=2.0e-9 // base is 1.0e-9 (X 2.0 for most runs) Traub 2005

float CondmaxTCRNMDA_C5FS=0.02e-9 // base is 0.10e-9 (X 0.2 for most runs)  Traub 2005

float CondmaxP23FRBAMPA_C5FS=2.0e-9 // base is 1.0e-9 (X 2.0 for most runs) Traub 2005

float CondmaxP23FRBNMDA_C5FS=0.02e-9 // base is 0.10e-9 (X 0.2 for most runs)  Traub 2005

float CondmaxP5RSAMPA_C5FS=6.0e-9 // base is 3.0e-9 (X 2.0 for most runs) Traub 2005

float CondmaxP5RSNMDA_C5FS=0.02e-9 // base is 0.10e-9 (X 0.2 for most runs) Traub 2005

//ST4RS

float CondmaxP23RSAMPA_ST4RS=0.2e-9 // base is 0.1e-9 (X 2.0 for most runs) Traub 2005

float CondmaxP23RSNMDA_ST4RS=0.025e-9 // base is 0.01e-9 (X 2.5 for most runs)  Traub 2005

float CondmaxB23FSGABAa_ST4RS=0.1e-9 // base is 0.1e-9 Traub 2005

float CondmaxP5IBAMPA_ST4RS=1.0e-9 // base is 0.5e-9 (X 2.0 for most runs) Traub 2005

float CondmaxP5IBNMDA_ST4RS=0.125e-9 // base is 0.05e-9 (X 2.5 for most runs) Traub 2005

float CondmaxB5FSGABAa_ST4RS=1.5e-9 // base is 1.5e-9 Traub 2005

float CondmaxP6RSAMPA_ST4RS=1.0e-9 // base is 0.5e-9 (X 2.0 for most runs) Traub 2005

float CondmaxP6RSNMDA_ST4RS=0.125e-9 // base is 0.05e-9 (X 2.5 for most runs) Traub 2005

float CondmaxC23FSGABAa_ST4RS=0.1e-9 // base is 0.1e-9 Traub 2005

float CondmaxC5FSGABAa_ST4RS=1.5e-9 // base is 1.5e-9 Traub 2005

float CondmaxST4RSAMPA_ST4RS=3.0e-9 // base is 1.0e-9 (X 2.0 for most runs) Traub 2005
// Traub 2005 uses a "low" state of base X 0.25, or a "high" state of base X 2.0

float CondmaxST4RSNMDA_ST4RS=0.125e-9 // base is 0.10e-9 (X 2.5 for most runs) Traub 2005

float CondmaxI23LTSGABAa_ST4RS=0.01e-9 // base is 0.01e-9 Traub 2005

float CondmaxI5LTSGABAa_ST4RS=0.01e-9 // base is 0.01e-9 Traub 2005

float CondmaxTCRAMPA_ST4RS=2.0e-9 // base is 1.0e-9 (X 2.0 for most runs) Traub 2005

float CondmaxTCRNMDA_ST4RS=0.25e-9 // base is 0.10e-9 (X 2.5 for most runs)  Traub 2005

float CondmaxP23FRBAMPA_ST4RS=0.2e-9 // base is 0.1e-9 (X 2.0 for most runs) Traub 2005

float CondmaxP23FRBNMDA_ST4RS=0.025e-9 // base is 0.01e-9 (X 2.5 for most runs)  Traub 2005

float CondmaxP5RSAMPA_ST4RS=1.0e-9 // base is 0.5e-9 (X 2.0 for most runs) Traub 2005

float CondmaxP5RSNMDA_ST4RS=0.15e-9 // base is 0.05e-9 (X 2.5 for most runs) Traub 2005

//I23LTS

float CondmaxP23RSAMPA_I23LTS=4.0e-9 // base is 2.0e-9 (X 2.0 for most runs) Traub 2005

float CondmaxP23RSNMDA_I23LTS=0.03e-9 // base is 0.15e-9 (X 0.2 for most runs)  Traub 2005

float CondmaxB23FSGABAa_I23LTS=0.5e-9 // base is 0.5e-9 Traub 2005

float CondmaxP5IBAMPA_I23LTS=2.0e-9 // base is 1.0e-9 (X 2.0 for most runs) Traub 2005

float CondmaxP5IBNMDA_I23LTS=0.03e-9 // base is 0.15e-9 (X 0.2 for most runs) Traub 2005

float CondmaxP6RSAMPA_I23LTS=2.0e-9 // base is 1.0e-9 (X 2.0 for most runs) Traub 2005

float CondmaxP6RSNMDA_I23LTS=0.02e-9 // base is 0.10e-9 (X 0.2 for most runs) Traub 2005

float CondmaxST4RSAMPA_I23LTS=2.0e-9 // base is 1.0e-9 (X 2.0 for most runs) Traub 2005

float CondmaxST4RSNMDA_I23LTS=0.03e-9 // base is 0.15e-9 (X 0.2 for most runs) Traub 2005

float CondmaxI23LTSGABAa_I23LTS=0.05e-9 // base is 0.05e-9 Traub 2005

float CondmaxI5LTSGABAa_I23LTS=0.05e-9 // base is 0.05e-9 Traub 2005

float CondmaxP23FRBAMPA_I23LTS=4.0e-9 // base is 2.0e-9 (X 2.0 for most runs) Traub 2005

float CondmaxP23FRBNMDA_I23LTS=0.02e-9 // base is 0.10e-9 (X 0.2 for most runs)  Traub 2005

float CondmaxP5RSAMPA_I23LTS=2.0e-9 // base is 1.0e-9 (X 2.0 for most runs) Traub 2005

float CondmaxP5RSNMDA_I23LTS=0.03e-9 // base is 0.15e-9 (X 0.2 for most runs) Traub 2005

//I5LTS

float CondmaxP23RSAMPA_I5LTS=2.0e-9 // base is 1.0e-9 (X 2.0 for most runs) Traub 2005

float CondmaxP23RSNMDA_I5LTS=0.03e-9 // base is 0.15e-9 (X 0.2 for most runs)  Traub 2005

float CondmaxP5IBAMPA_I5LTS=4.0e-9 // base is 2.0e-9 (X 2.0 for most runs) Traub 2005

float CondmaxP5IBNMDA_I5LTS=0.03e-9 // base is 0.15e-9 (X 0.2 for most runs) Traub 2005

float CondmaxB5FSGABAa_I5LTS=0.7e-9 // base is 0.7e-9 Traub 2005

float CondmaxP6RSAMPA_I5LTS=4.0e-9 // base is 2.0e-9 (X 2.0 for most runs) Traub 2005

float CondmaxP6RSNMDA_I5LTS=0.02e-9 // base is 0.10e-9 (X 0.2 for most runs) Traub 2005

float CondmaxST4RSAMPA_I5LTS=2.0e-9 // base is 1.0e-9 (X 2.0 for most runs) Traub 2005

float CondmaxST4RSNMDA_I5LTS=0.03e-9 // base is 0.15e-9 (X 0.2 for most runs) Traub 2005

float CondmaxI23LTSGABAa_I5LTS=0.05e-9 // base is 0.05e-9 Traub 2005

float CondmaxI5LTSGABAa_I5LTS=0.05e-9 // base is 0.05e-9 Traub 2005

float CondmaxP23FRBAMPA_I5LTS=2.0e-9 // base is 1.0e-9 (X 2.0 for most runs) Traub 2005

float CondmaxP23FRBNMDA_I5LTS=0.02e-9 // base is 0.10e-9 (X 0.2 for most runs)  Traub 2005

float CondmaxP5RSAMPA_I5LTS=4.0e-9 // base is 2.0e-9 (X 2.0 for most runs) Traub 2005

float CondmaxP5RSNMDA_I5LTS=0.02e-9 // base is 0.10e-9 (X 0.2 for most runs) Traub 2005

//TCR

float CondmaxP6RSAMPA_TCR=1.50e-9 // base is 0.75e-9 (X 2.0 for most runs) Traub 2005

float CondmaxP6RSNMDA_TCR=0.015e-9 // base is 0.075e-9 (X 0.2 for most runs) Traub 2005

float CondmaxnRTGABAa_TCR=1.4e-9 // base is 1.4e-9 Traub 2005
// In the 2005 Traub model, this conductance is uniformly randomly distributed 
// from 0.7 - 2.1 nS

//nRT

float CondmaxP6RSAMPA_nRT=1.0e-9 // base is 0.5e-9 (X 2.0 for most runs) Traub 2005

float CondmaxP6RSNMDA_nRT=0.01e-9 // base is 0.05e-9 (X 0.2 for most runs) Traub 2005

float CondmaxTCRAMPA_nRT=1.50e-9 // base is 0.75e-9 (X 2.0 for most runs) Traub 2005

float CondmaxTCRNMDA_nRT=0.03e-9 // base is 0.15e-9 (X 0.2 for most runs) Traub 2005

float CondmaxnRTGABAa_nRT=0.30e-9 // base is 0.30e-9 Traub 2005

//P23FRB

float CondmaxP23RSAMPA_P23FRB=0.5e-9 // base is 0.25e-9 (X 2.0 for most runs) Traub 2005

float CondmaxP23RSNMDA_P23FRB=0.0625e-9 // base is 0.025e-9 (X 2.5 for most runs) Traub 2005

float CondmaxB23FSGABAa_P23FRB=1.2e-9 // base is 1.2e-9 Traub 2005

float CondmaxP5IBAMPA_P23FRB=1.0e-9 // base is 0.5e-9 (X 2.0 for most runs) Traub 2005

float CondmaxP5IBNMDA_P23FRB=0.125e-9 // base is 0.05e-9 (X 2.5 for most runs) Traub 2005

float CondmaxP6RSAMPA_P23FRB=1.00e-9 // base is 0.50e-9 (X 2.0 for most runs) Traub 2005

float CondmaxP6RSNMDA_P23FRB=0.125e-9 // base is 0.05e-9 (X 2.5 for most runs) Traub 2005

float CondmaxC23FSGABAa_P23FRB=1.2e-9 // base is 1.2e-9 Traub 2005

float CondmaxC5FSGABAa_P23FRB=1.0e-9 // base is 1.0e-9 Traub 2005

float CondmaxST4RSAMPA_P23FRB=2.00e-9 // base is 1.00e-9 (X 2.0 for most runs) Traub 2005

float CondmaxST4RSNMDA_P23FRB=0.75e-9 // base is 0.10e-9 (X 2.5 for most runs) Traub 2005

float CondmaxI23LTSGABAa_P23FRB=0.01e-9 // base is 0.01e-9 Traub 2005

float CondmaxI5LTSGABAa_P23FRB=0.01e-9 // base is 0.01e-9 Traub 2005

float CondmaxTCRAMPA_P23FRB=1.00e-9 // base is 0.50e-9 (X 2.0 for most runs) Traub 2005

float CondmaxTCRNMDA_P23FRB=0.125e-9 // base is 0.05e-9 (X 2.5 for most runs) Traub 2005

float CondmaxP23FRBAMPA_P23FRB=0.5e-9 // base is 0.25e-9 (X 2.0 for most runs) Traub 2005

float CondmaxP23FRBNMDA_P23FRB=0.0625e-9 // base is 0.025e-9 (X 2.5 for most runs) Traub 2005

float CondmaxP5RSAMPA_P23FRB=1.0e-9 // base is 0.5e-9 (X 2.0 for most runs) Traub 2005

float CondmaxP5RSNMDA_P23FRB=0.125e-9 // base is 0.05e-9 (X 2.5 for most runs) Traub 2005

//P5RS

float CondmaxP23RSAMPA_P5RS=0.20e-9 // base is 0.10e-9 (X 2.0 for most runs) Traub 2005

float CondmaxP23RSNMDA_P5RS=0.025e-9 // base is 0.010e-9 (X 2.5 for most runs) Traub 2005

float CondmaxB5FSGABAa_P5RS=0.7e-9 // base is 0.7e-9 Traub 2005

float CondmaxP5IBAMPA_P5RS=4.00e-9 // base is 2.00e-9 (X 2.0 for most runs) Traub 2005

float CondmaxP5IBNMDA_P5RS=0.50e-9 // base is 0.20e-9 (X 2.5 for most runs)  Traub 2005

float CondmaxP6RSAMPA_P5RS=2.00e-9 // base is 1.00e-9 (X 2.0 for most runs) Traub 2005

float CondmaxP6RSNMDA_P5RS=0.25e-9 // base is 0.10e-9 (X 2.5 for most runs)  Traub 2005

float CondmaxC23FSGABAa_P5RS=1.0e-9 // base is 1.0e-9 Traub 2005

float CondmaxC5FSGABAa_P5RS=1.0e-9 // base is 1.0e-9 Traub 2005

float CondmaxST4RSAMPA_P5RS=2.00e-9 // base is 1.00e-9 (X 2.0 for most runs) Traub 2005

float CondmaxST4RSNMDA_P5RS=0.75e-9 // base is 0.10e-9 (X 2.5 for most runs)  Traub 2005

float CondmaxI23LTSGABAa_P5RS=0.02e-9 // base is 0.02e-9 Traub 2005

float CondmaxI5LTSGABAa_P5RS=0.02e-9 // base is 0.02e-9 Traub 2005

float CondmaxTCRAMPA_P5RS=3.00e-9 // base is 1.50e-9 (X 2.0 for most runs) Traub 2005

float CondmaxTCRNMDA_P5RS=0.375e-9 // base is 0.15e-9 (X 2.5 for most runs) Traub 2005

float CondmaxP23FRBAMPA_P5RS=0.20e-9 // base is 0.10e-9 (X 2.0 for most runs) Traub 2005

float CondmaxP23FRBNMDA_P5RS=0.025e-9 // base is 0.010e-9 (X 2.5 for most runs) Traub 2005

float CondmaxP5RSAMPA_P5RS=2.0e-9 // base is 1.0e-9 (X 2.0 for most runs) Traub 2005

float CondmaxP5RSNMDA_P5RS=0.25e-9 // base is 0.10e-9 (X 2.5 for most runs) Traub 2005

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