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Distinct current modules shape cellular dynamics in model neurons (Alturki et al 2016)
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Model Information
Model File
Citations
Accession:
223649
" ... We hypothesized that currents are grouped into distinct modules that shape specific neuronal characteristics or signatures, such as resting potential, sub-threshold oscillations, and spiking waveforms, for several classes of neurons. For such a grouping to occur, the currents within one module should have minimal functional interference with currents belonging to other modules. This condition is satisfied if the gating functions of currents in the same module are grouped together on the voltage axis; in contrast, such functions are segregated along the voltage axis for currents belonging to different modules. We tested this hypothesis using four published example case models and found it to be valid for these classes of neurons. ..."
Reference:
1 .
Alturki A, Feng F, Nair A, Guntu V, Nair SS (2016) Distinct current modules shape cellular dynamics in model neurons.
Neuroscience
334
:309-331
[
PubMed
]
Model Information
(Click on a link to find other models with that property)
Model Type:
Neuron or other electrically excitable cell;
Brain Region(s)/Organism:
Hippocampus;
Amygdala;
Cell Type(s):
Abstract single compartment conductance based cell;
Channel(s):
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment:
NEURON;
Model Concept(s):
Simplified Models;
Activity Patterns;
Oscillations;
Methods;
Olfaction;
Implementer(s):
Download the displayed file
/
AlturkiEtAl2016
2_Pospischil
Original
README.html
*
Other models using README.html:
Hodgkin-Huxley models of different classes of cortical neurons (Pospischil et al. 2008)
cadecay_destexhe.mod
*
Other models using cadecay_destexhe.mod:
Cortical feedback alters visual response properties of dLGN relay cells (Martínez-Cañada et al 2018)
Distinct current modules shape cellular dynamics in model neurons (Alturki et al 2016)
Hodgkin-Huxley models of different classes of cortical neurons (Pospischil et al. 2008)
Low Threshold Calcium Currents in TC cells (Destexhe et al 1998)
Pyramidal Neuron: Deep, Thalamic Relay and Reticular, Interneuron (Destexhe et al 1998, 2001)
Rat LGN Thalamocortical Neuron (Connelly et al 2015, 2016)
HH_traub.mod
*
Other models using HH_traub.mod:
Hodgkin-Huxley models of different classes of cortical neurons (Pospischil et al. 2008)
IL_gutnick.mod
IM_cortex.mod
IT_huguenard.mod
demo_IN_FS.hoc
*
Other models using demo_IN_FS.hoc:
Distinct current modules shape cellular dynamics in model neurons (Alturki et al 2016)
Hodgkin-Huxley models of different classes of cortical neurons (Pospischil et al. 2008)
demo_PY_IB.hoc
*
Other models using demo_PY_IB.hoc:
Distinct current modules shape cellular dynamics in model neurons (Alturki et al 2016)
Hodgkin-Huxley models of different classes of cortical neurons (Pospischil et al. 2008)
demo_PY_IBR.hoc
*
Other models using demo_PY_IBR.hoc:
Distinct current modules shape cellular dynamics in model neurons (Alturki et al 2016)
Hodgkin-Huxley models of different classes of cortical neurons (Pospischil et al. 2008)
demo_PY_LTS.hoc
*
Other models using demo_PY_LTS.hoc:
Distinct current modules shape cellular dynamics in model neurons (Alturki et al 2016)
Hodgkin-Huxley models of different classes of cortical neurons (Pospischil et al. 2008)
demo_PY_RS.hoc
*
Other models using demo_PY_RS.hoc:
Distinct current modules shape cellular dynamics in model neurons (Alturki et al 2016)
Hodgkin-Huxley models of different classes of cortical neurons (Pospischil et al. 2008)
fig5b.jpg
*
Other models using fig5b.jpg:
Hodgkin-Huxley models of different classes of cortical neurons (Pospischil et al. 2008)
mosinit.hoc
*
Other models using mosinit.hoc:
Distinct current modules shape cellular dynamics in model neurons (Alturki et al 2016)
Hodgkin-Huxley models of different classes of cortical neurons (Pospischil et al. 2008)
rundemo.hoc
*
Other models using rundemo.hoc:
Distinct current modules shape cellular dynamics in model neurons (Alturki et al 2016)
Hodgkin-Huxley models of different classes of cortical neurons (Pospischil et al. 2008)
sIN_template
*
Other models using sIN_template:
Distinct current modules shape cellular dynamics in model neurons (Alturki et al 2016)
Hodgkin-Huxley models of different classes of cortical neurons (Pospischil et al. 2008)
sPY_template
*
Other models using sPY_template:
Distinct current modules shape cellular dynamics in model neurons (Alturki et al 2016)
Hodgkin-Huxley models of different classes of cortical neurons (Pospischil et al. 2008)
sPYb_template
*
Other models using sPYb_template:
Distinct current modules shape cellular dynamics in model neurons (Alturki et al 2016)
Hodgkin-Huxley models of different classes of cortical neurons (Pospischil et al. 2008)
sPYbr_template
*
Other models using sPYbr_template:
Distinct current modules shape cellular dynamics in model neurons (Alturki et al 2016)
Hodgkin-Huxley models of different classes of cortical neurons (Pospischil et al. 2008)
sPYr_template
*
Other models using sPYr_template:
Distinct current modules shape cellular dynamics in model neurons (Alturki et al 2016)
Hodgkin-Huxley models of different classes of cortical neurons (Pospischil et al. 2008)
load_file("nrngui.hoc") load_file("rundemo.hoc") print "Select a cell then press Init & Run button"
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