This is to replicate Fig.A3A in Alturki et al., 2016
AFTER YOU COMPILE THE FILES (see below):
ORIGINAL
To run the original model of Pospischil et al:
1- Click on mosinit.hoc, several windows will automatically pop up
2- Select IClamp from the "I/V Clamp Electrode" window
3- Select the cell type from the list in the "Simulations of cortical cells" window, we studied 4 cell types:
- RS cell (the 1st one in the list)
- Bursting (2nd in the list)
- Low Threshold Spiking LTS (4th in the list)
- FS (5th in the list)
4- After selecting the cell type, click on Init & Run fom the "RunControl" window
SEGREGATED
To run the segregated model of Pospischil et al:
1- Click on mosinit.hoc, several windows will automatically pop up
2- Select IClamp from the "I/V Clamp Electrode" window
3- Select the cell type from the list in the "Simulations of cortical cells" window.We studied 4 cell types:
- RS cell (the 1st one in the list)
- Bursting (2nd in the list)
- Low Threshold Spiking LTS (4th in the list)
- FS (5th in the list)
4- After selecting the cell type, click on Init & Run fom the "RunControl" window
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TO COMPILE AND RUN THE MODEL IN THE FOLDERS 'ORIGINAL' OR 'SEGREGATED' DO THE FOLLOWING:
Under unix systems:
to compile the mod files use the command
nrnivmodl
and run the simulation hoc file with the command
nrngui FILENAME.hoc
Under Windows systems:
to compile the mod files use the "mknrndll" command.
A double click on the simulation file
FILENAME.hoc
will open the simulation window.
Under MAC OS X:
Drag and drop the FILE folder onto the mknrndll icon in the NEURON
application folder. When the mod files are finished compiling, double click on the simulation file FILENAME.hoc
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