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Rat LGN Thalamocortical Neuron (Connelly et al 2015, 2016)
 
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Model Information
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Accession:
223891
" ... Here, combining data from fluorescence-targeted dendritic recordings and Ca2+ imaging from low-threshold spiking cells in rat brain slices with computational modeling, the cellular mechanism responsible for LTS (Low Threshold Spike) generation is established. ..." " ... Using dendritic recording, 2-photon glutamate uncaging, and computational modeling, we investigated how rat dorsal lateral geniculate nucleus thalamocortical neurons integrate excitatory corticothalamic feedback. ..."
References:
1 .
Connelly WM, Crunelli V, Errington AC (2016) Passive Synaptic Normalization and Input Synchrony-Dependent Amplification of Cortical Feedback in Thalamocortical Neuron Dendrites.
J Neurosci
36
:3735-54
[
PubMed
]
2 .
Connelly WM, Crunelli V, Errington AC (2015) The Global Spike: Conserved Dendritic Properties Enable Unique Ca2+ Spike Generation in Low-Threshold Spiking Neurons.
J Neurosci
35
:15505-22
[
PubMed
]
Model Information
(Click on a link to find other models with that property)
Model Type:
Neuron or other electrically excitable cell;
Brain Region(s)/Organism:
Thalamus;
Cell Type(s):
Thalamus geniculate nucleus/lateral principal GLU cell;
Channel(s):
I T low threshold;
I Calcium;
I h;
Gap Junctions:
Receptor(s):
NMDA;
AMPA;
Gene(s):
Transmitter(s):
Glutamate;
Simulation Environment:
NEURON;
Model Concept(s):
Dendritic Action Potentials;
Detailed Neuronal Models;
Action Potentials;
Active Dendrites;
Action Potential Initiation;
Calcium dynamics;
Implementer(s):
Connelly, William [connelly.bill at gmail.com];
Search NeuronDB
for information about:
Thalamus geniculate nucleus/lateral principal GLU cell
;
AMPA
;
NMDA
;
I T low threshold
;
I h
;
I Calcium
;
Glutamate
;
/
ConnellyEtAl2015_2016
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