CRH modulates excitatory transmission and network physiology in hippocampus (Gunn et al. 2017)

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Accession:225906
This model simulates the effects of CRH on sharp waves in a rat CA1/CA3 model. It uses the frequency of the sharp waves as an output of the network.
References:
1 . Taxidis J, Coombes S, Mason R, Owen MR (2012) Modeling sharp wave-ripple complexes through a CA3-CA1 network model with chemical synapses. Hippocampus 22:995-1017 [PubMed]
2 . Gunn BG, Cox CD, Chen Y, Frotscher M, Gall CM, Baram TZ, Lynch G (2017) The Endogenous Stress Hormone CRH Modulates Excitatory Transmission and Network Physiology in Hippocampus. Cereb Cortex 27:4182-4198 [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type: Connectionist Network;
Brain Region(s)/Organism: Hippocampus;
Cell Type(s): Abstract Wang-Buzsaki neuron; Pinsky-Rinzel CA1/3 pyramidal cell ;
Channel(s):
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s): Glutamate; Gaba;
Simulation Environment: Brian; Python;
Model Concept(s): Brain Rhythms;
Implementer(s): Cox, Conor [cdcox1 at gmail.com];
Search NeuronDB for information about:  Gaba; Glutamate;
 
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