Hotspots of dendritic spine turnover facilitates new spines and NN sparsity (Frank et al 2018)

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Accession:227087
Model for the following publication: Adam C. Frank, Shan Huang, Miou Zhou, Amos Gdalyahu, George Kastellakis, Panayiota Poirazi, Tawnie K. Silva, Ximiao Wen, Joshua T. Trachtenberg, and Alcino J. Silva Hotspots of Dendritic Spine Turnover Facilitate Learning-related Clustered Spine Addition and Network Sparsity
Reference:
1 . Frank AC, Huang S, Zhou M, Gdalyahu A, Kastellakis G, Silva TK, Lu E, Wen X, Poirazi P, Trachtenberg JT, Silva AJ (2018) Hotspots of dendritic spine turnover facilitate clustered spine addition and learning and memory. Nat Commun 9:422 [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type: Neuron or other electrically excitable cell; Connectionist Network;
Brain Region(s)/Organism:
Cell Type(s): Abstract integrate-and-fire leaky neuron with dendritic subunits;
Channel(s):
Gap Junctions:
Receptor(s): NMDA;
Gene(s):
Transmitter(s):
Simulation Environment: C or C++ program; MATLAB;
Model Concept(s): Active Dendrites; Synaptic Plasticity;
Implementer(s): Kastellakis, George [gkastel at gmail.com];
Search NeuronDB for information about:  NMDA;
function [uniqueEntries,numberOfOccurences,whereIdx] = countEntries(m,isRow, keepNaN)
%COUNTENTRIES returns all unique entries (sorted) in the array m and how many times the respective entries occured
%
%SYNOPSIS [uniqueEntries,numberOfOccurences] = countEntries(m,isRow)
%
%INPUT  m          : any matrix (not cells or structs)
%       isRow(opt) : should rows be counted or not [1/{0}]
%                       (if it's cols, transpose m before calling the function!)
%       keepNaN (opt) : count NaN as entry? [{1}/0] If 0, NaNs (or
%                       NaN-containing rows) are removed after sorting, so
%                       that whereIdx still refers to the original position
%                       of the uniqueEntries in the input array.
%
%OUTPUT uniqueEntries : unique(m)
%                       if only one output argument is requested,
%                       countEntries returns [uniqueEntries,#ofOcc]
%       numberOfOccurences : how many times the unique entries appear in m
%       whereIdx      : where in m do the entries appear? (m = uniqueEntries(whereIdx,:))
%
%
%c: 11/03, jonas
%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%


%---test input
if iscell(m) || isstruct(m)
    error('cells and structs are not supportet as input');
end

if nargin < 2 || isempty(isRow)
    doRow = 0;
else
    if isRow == 1;
        doRow = 1;
    elseif isRow == 0
        doRow = 0;
    else
        error('input argument isRow has to be 1 or 0!')
    end
end
if nargin < 3 || isempty(keepNaN)
    keepNaN = true;
end
%---end test input



if ~doRow %do the fast method
    
    %make m into a vector
    m = m(:);
    
    %get unique Entries. sort them first, though
    m = sort(m);
    
    [uniqueEntries, uniqueIdx, whereIdx] = unique(m);
    
    if ~keepNaN
        % remove NaN, inf
        badIdx = find(~isfinite(uniqueEntries));
        uniqueEntries(badIdx) = [];
        uniqueIdx(badIdx) = [];
        whereIdx(ismember(whereIdx,badIdx)) = [];
    end
    
    %uniqueIdx returns the last occurence of the respective unique entry
    %having sorted m before, we can now count the number of occurences
    if size(uniqueEntries,1)>size(uniqueEntries,2)
        uniqueIdx = [0;uniqueIdx];
    else
        uniqueIdx = [0,uniqueIdx];
    end
    
    numberOfOccurences = diff(uniqueIdx); 
    
else %do it the complicated way
    
    %we do not care about the ordering of the matrix here: if the user
    %specified rows, he/she wanted a columnVector as output (or should read the help)
    [uniqueEntries, dummy, uniqueIdx] = unique(m,'rows');
    
    %rember output
    whereIdx = uniqueIdx;
    
    if ~keepNaN
        % remove NaN, inf
        badIdx = find(any(~isfinite(uniqueEntries),2));
        uniqueEntries(badIdx,:) = [];
        whereIdx(ismember(whereIdx,badIdx)) = [];
        uniqueIdx = whereIdx;
    end
    
    %uniqueIdx returns the indexList where uniqueEntriy #x occurs.
    %We will now sort this list and take a diff to find where this index
    %changes.
    %adding zero and length(uniqueIndex) to the vector, we can now via
    %another diff see how many entries there are (see example)
    
    %example m: [11,11,22,33,33,22,22,22,44,11]
    %corresponding uniqueEntries, uniqueIdx: [11,22,33,44] / [1 1 2 3 3 2 2 2 4 1]
    
    %sort: [1     1     1     2     2     2     2     3     3     4]
    sortedIdx = sort(uniqueIdx);
    
    %diff: [0     0     1     0     0     0     1     0     1]
    sortedIdxDiff = diff(sortedIdx);
    
    %find and add entries: [0     3     7     9    10]
    changeValueIdx = [0;find(sortedIdxDiff);length(uniqueIdx)];
    
    %diff again for the numberOfOccurences: [3     4     2     1]
    numberOfOccurences = diff(changeValueIdx);
end

if nargout < 2
    uniqueEntries = [uniqueEntries,numberOfOccurences];
end

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