Robust transmission in the inhibitory Purkinje Cell to Cerebellar Nuclei pathway (Abbasi et al 2017)

 Download zip file 
Help downloading and running models

1 . Abbasi S, Hudson AE, Maran SK, Cao Y, Abbasi A, Heck DH, Jaeger D (2017) Robust Transmission of Rate Coding in the Inhibitory Purkinje Cell to Cerebellar Nuclei Pathway in Awake Mice PLOS Computational Biology
2 . Steuber V, Schultheiss NW, Silver RA, De Schutter E, Jaeger D (2011) Determinants of synaptic integration and heterogeneity in rebound firing explored with data-driven models of deep cerebellar nucleus cells. J Comput Neurosci 30:633-58 [PubMed]
3 . Steuber V, Jaeger D (2013) Modeling the generation of output by the cerebellar nuclei. Neural Netw 47:112-9 [PubMed]
4 . Steuber V, De Schutter E, Jaeger D (2004) Passive models of neurons in the deep cerebellar nuclei: the effect of reconstruction errors Neurocomputing 58-60:563-568
5 . Luthman J, Hoebeek FE, Maex R, Davey N, Adams R, De Zeeuw CI, Steuber V (2011) STD-dependent and independent encoding of input irregularity as spike rate in a computational model of a cerebellar nucleus neuron. Cerebellum 10:667-82 [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type: Neuron or other electrically excitable cell;
Brain Region(s)/Organism: Cerebellum;
Cell Type(s): Cerebellum deep nucleus neuron;
Channel(s): I h; I T low threshold; I L high threshold; I Na,p; I Na,t; I K,Ca; I K;
Gap Junctions:
Receptor(s): AMPA; NMDA; GabaA;
Transmitter(s): Gaba; Glutamate;
Simulation Environment: GENESIS;
Model Concept(s): Synaptic Integration;
Implementer(s): Jaeger, Dieter [djaeger at];
Search NeuronDB for information about:  GabaA; AMPA; NMDA; I Na,p; I Na,t; I L high threshold; I T low threshold; I K; I h; I K,Ca; Gaba; Glutamate;
function [sv,sp,fm] = spsvd(data,params,mdkp)
% Space frequency SVD of input data - continuous processes
% Usage: [sv,sp,fm] = spsvd(data,params,mdkp)
% Inputs:
% data       (data matrix in timexchannels form)-required
%       params      structure containing parameters - params has the
%       following fields: tapers, Fs, fpass, pad
%           tapers : precalculated tapers from dpss or in the one of the following
%                    forms: 
%                   (1) A numeric vector [TW K] where TW is the
%                       time-bandwidth product and K is the number of
%                       tapers to be used (less than or equal to
%                       2TW-1). 
%                   (2) A numeric vector [W T p] where W is the
%                       bandwidth, T is the duration of the data and p 
%                       is an integer such that 2TW-p tapers are used. In
%                       this form there is no default i.e. to specify
%                       the bandwidth, you have to specify T and p as
%                       well. Note that the units of W and T have to be
%                       consistent: if W is in Hz, T must be in seconds
%                       and vice versa. Note that these units must also
%                       be consistent with the units of params.Fs: W can
%                       be in Hz if and only if params.Fs is in Hz.
%                       The default is to use form 1 with TW=3 and K=5
%	        Fs 	        (sampling frequency) -- optional. Defaults to 1.
%           fpass       (frequency band to be used in the calculation in the form
%                                   [fmin fmax])- optional. 
%                                   Default all frequencies between 0 and Fs/2
%	        pad		    (padding factor for the FFT) - optional (can take values -1,0,1,2...). 
%                    -1 corresponds to no padding, 0 corresponds to padding
%                    to the next highest power of 2 etc.
%			      	 e.g. For N = 500, if PAD = -1, we do not pad; if PAD = 0, we pad the FFT
%			      	 to 512 points, if pad=1, we pad to 1024 points etc.
%			      	 Defaults to 0.
% mdkp       (number of dimensions to be kept)-optional. Default is the
%               maximum possible modes determined by taper parameters
% Outputs:
% sv sp fm  : singular values, space modes, frequency modes

if nargin < 1; error('Need data'); end;
if nargin < 2 || isempty(params); params=[]; end;
clear err trialave params
nfft=max(2^(nextpow2(N)+pad),N);% number of points in fft
if nargin<3 || isempty(mdkp); mdkp=min(K,NCHAN);
elseif mdkp > min(K,NCHAN); error('mdkp has to be less than both K and NCHAN');end;

tvec=repmat(tvec,[1 K]);
for j=1:nf 
%     for k=1:K
%       proj(:,k)=tapers(:,k).*exp(-f0*tvec');
%     end
    tmp=data'*proj; % projected data
    [u,s,v]= svd(tmp,0); % svd 
    for mk=1:mdkp, 

Loading data, please wait...