//genesis
/*************************** MS Model, Version 5.10 **********************
**************************** globals.g **********************
Tom Sheehan tsheeha2@gmu.edu thsheeha@vt.edu 703-538-8361
*******************************************************************************
The capatilized parameters defined below are global and visable to all files
Capatilized parameters should be treated as constants
******************************************************************************/
/* AB: Comments indicate the qfactor used with the various channels
* conductance of CaN and CaL12 sum the inactivating and non-inactivating channel
* conductances from the previous model
*/
float ELEAK = -0.070
float PI = 3.1415926
float RA = 1.0;
float RM = 8.69565217;
float CM = 0.01;
float EREST_ACT = -0.08
float TEMPERATURE = 35
float temperature = 35 // some old MS commands need it
str CA_BUFF_1 = "Ca_difshell_1" // L and T type channels
str CA_BUFF_2 = "Ca_difshell_2" // coupled to the other channels
str CA_BUFF_3 = "Ca_difshell_3" // all calcium channels
int CaDyeFlag = 0 // flags of calcium dye. "0" means NO calcium dyes.
// flag =2 : Fluo-4
// flag =3 : Fluo-5F
int shellMode = 1 // we have two shell-modes:
// mode = 0 : detailed multi-shell model, using "difshell" object
// mode = 1 : simple calcium pool adopted from Sabatini's work(Sabatini, 2001, 2004)
//parameters determined by hand tuning to match spike width, AHP shape &, fI curve
//spike width with these globals plus spines = 0.88 ms
str gNaFprox={90000}*1 //qfactor = 1.2 90000
str gNaFmid={975}*0.1
str gNaFdist={975}*0.1
str gKAfprox={3214}*1 //qfactor=1.5 for inact
str gKAfmid={471}*1 //1/qfactor=1.5 for act!!!
str gKAfdist={314}*0.3
str gKAsprox={277}*0.5 //qfactor=2
str gKAsdist={22.9}*0.5
str gKIRsoma= 4.2*4 //qfactor = 0.5; gKIR=4.2
str gKIRdist= 4.2*4
str gKDR={7.25}*1 //qfactor = 0.5
float gCaL13 = 1.0625e-7 //qfactor=2
float gCaT = 0.5875e-8
float gCaR = 6.5e-7
// float gCaQ = 1.5e-7
float gCaN = 2.5e-7 //qfactor=2
float gCaL12 = 0.8375e-7 //qfactor=2
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