... Here, we present T2N, a powerful
interface to control NEURON with Matlab and TREES toolbox, which
supports generating models stable over a broad range of reconstructed
and synthetic morphologies. We illustrate this for a novel,
highly-detailed active model of dentate granule cells (GCs)
replicating a wide palette of experiments from various labs. By
implementing known differences in ion channel composition and
morphology, our model reproduces data from mouse or rat, mature or
adult-born GCs as well as pharmacological interventions and epileptic
conditions.
... T2N is suitable for creating robust models useful for
large-scale networks that could lead to novel predictions. ..."
See modeldb accession number 231818 for NEURON only code.
Reference:
1 .
Beining M, Mongiat LA, Schwarzacher SW, Cuntz H, Jedlicka P (2017) T2N as a new tool for robust electrophysiological modeling demonstrated for mature and adult-born dentate granule cells eLife
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