In this paper we introduce a new statistical view of long-term synaptic plasticity, in which the postsynaptic responses are optimised towards a bound (or target). This in turn explains a wide range of experimental data.
Reference:
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Costa RP, Padamsey Z, D'Amour JA, Emptage NJ, Froemke RC, Vogels TP (2017) Synaptic Transmission Optimization Predicts Expression Loci of Long-Term Plasticity. Neuron 96:177-189.e7 [PubMed]
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