Electrical activity of the suprachiasmatic nuclei (Stinchcombe et al. 2017)

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A network of SCN neurons coupled though GABA synapses with a light input current.
1 . Diekman CO, Belle MD, Irwin RP, Allen CN, Piggins HD, Forger DB (2013) Causes and consequences of hyperexcitation in central clock neurons. PLoS Comput Biol 9:e1003196 [PubMed]
2 . Stinchcombe AR, Mouland JW, Wong KY, Lucas RJ, Forger DB (2017) Multiplexing Visual Signals in the Suprachiasmatic Nuclei. Cell Rep 21:1418-1425 [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type:
Brain Region(s)/Organism:
Cell Type(s): Suprachiasmatic nucleus (SCN) neuron;
Gap Junctions:
Transmitter(s): Gaba;
Simulation Environment: MATLAB;
Model Concept(s):
Implementer(s): Stinchcombe, Adam R [stinch at math.toronto.edu]; Forger, Daniel B [forger at umich.edu];
Search NeuronDB for information about:  Gaba;
This is the readme for the model associated with
Stinchcombe, AR et al., 'Multiplexing Visual Signals in the Suprachiasmatic Nuclei', Cell Reports, Volume 21, Issue 6, 1418-1425.

To run, enter "SCNephyssimulation" at the MATLAB command prompt. A raster plot will be generated showing the spike times of SCN neurons for a full field flash stimulus and a randomly generated connectivity. This code was developed in MATLAB R2017a.

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