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PKMZ synthesis and AMPAR regulation in late long-term synaptic potentiation (Helfer & Shultz 2018)
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Stochastic simulation of a set of molecular reactions that implement late long-term potentiation (L-LTP). The model is able to account for a wide range of empirical results, including induction and maintenance of late-phase LTP, cellular memory reconsolidation and the effects of different pharmaceutical interventions.
Helfer P, Shultz TR (2018) Coupled feedback loops maintain synaptic long-term potentiation: A computational model of PKMzeta synthesis and AMPA receptor trafficking.
PLoS Comput Biol
Helfer P, Shultz TR (2018) Coupled feedback loops maintain synaptic long-term potentiation: A computational model
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C or C++ program;
Long-term Synaptic Plasticity;
Helfer, Peter [peter.helfer at mail.mcgill.ca];
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