A computational model of oxytocin modulation of olfactory recognition memory (Linster & Kelsch 2019)

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Accession:257940
Model of olfactory bulb (OB) and anterior olfactory nucleus (AON) pyramidal cells. Includes olfactory sensory neurons, mitral cells, periglomerular, external tufted and granule interneurons and pyramidal cells. Can be built to include a feedback loop between OB and AON. Output consists of voltage and spikes over time in all neurons. Model can be stimulated with simulated odorants. The code submitted here has served for a number of modeling explorations of olfactory bulb and cortex. The model architecture is defined in "bulb.dat" with synapses defined in "channels.dat". The main function to run the model can be found in "neuron.c". Model architecture is constructed in "set.c" from types defined in "sim.c". A make file to create an executable is located in "neuron.mak".
Reference:
1 . Linster C, Kelsch W (2019) A computational model of oxytocin modulation of olfactory recognition memory. eNeuro [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type: Realistic Network;
Brain Region(s)/Organism: Olfactory bulb;
Cell Type(s): Olfactory bulb main mitral GLU cell; Olfactory bulb main interneuron periglomerular GABA cell; Olfactory bulb main interneuron granule MC GABA cell; Olfactory bulb main interneuron granule TC GABA cell; Olfactory bulb main tufted cell external;
Channel(s):
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment: C or C++ program;
Model Concept(s):
Implementer(s): Linster, Christiane [cl243 at cornell.edu];
Search NeuronDB for information about:  Olfactory bulb main mitral GLU cell; Olfactory bulb main interneuron periglomerular GABA cell; Olfactory bulb main interneuron granule MC GABA cell; Olfactory bulb main interneuron granule TC GABA cell;

typedef struct 	{
		int	from;
		int	too;
		} WIND;


enum BOOLEAN ALL;
enum BOOLEAN D_RECS;
enum BOOLEAN D_STIM;
enum BOOLEAN D_OUT;
enum BOOLEAN D_POT;
enum BOOLEAN D_SPIKES;
enum BOOLEAN D_ACT;
enum BOOLEAN D_GOUT;
enum BOOLEAN D_GPOT;
enum BOOLEAN D_MOUT;
enum BOOLEAN D_MPOT;
enum BOOLEAN D_FFTG;
enum BOOLEAN D_FFTM;
enum BOOLEAN D_VPOT;
enum BOOLEAN D_VOUT;


extern char 	*NTEXT ();
extern void	SELECT ();
extern void 	DESELECT ();
extern void 	RESET_COORD ();
extern void 	DRAW_MOLECULES ();
extern void	DRAW_FFT ();
extern void 	DRAW_CROSS ();
extern int	SHOW_CROSS ();
extern WIND 	DRAW ();
extern void 	SHOW ();


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