Large scale neocortical model for PGENESIS (Crone et al 2019)

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Accession:260267
This is model code for a large scale neocortical model based on Traub et al. (2005), modified to run on PGENESIS on supercomputing resources. "In this paper (Crone et al 2019), we evaluate the computational performance of the GEneral NEural SImulation System (GENESIS) for large scale simulations of neural networks. While many benchmark studies have been performed for large scale simulations with leaky integrate-and-fire neurons or neuronal models with only a few compartments, this work focuses on higher fidelity neuronal models represented by 50–74 compartments per neuron. ..."
Reference:
1 . Crone JC, Vindiola MM, Yu AB, Boothe DL, Beeman D, Oie KS, Franaszczuk PJ (2019) Enabling Large-Scale Simulations With the GENESIS Neuronal Simulator Frontiers in Neuroinformatics 13:69
Model Information (Click on a link to find other models with that property)
Model Type: Realistic Network;
Brain Region(s)/Organism: Neocortex;
Cell Type(s): Neocortex L2/3 pyramidal GLU cell; Neocortex L5/6 pyramidal GLU cell; Thalamus reticular nucleus GABA cell; Neocortex fast spiking (FS) interneuron; Neocortex layer 2-3 interneuron; Neocortex layer 5 interneuron; Neocortex spiking low threshold (LTS) neuron; Neocortex spiny stellate cell;
Channel(s): I Sodium; I Potassium; I Calcium;
Gap Junctions:
Receptor(s): AMPA; NMDA; GabaA;
Gene(s):
Transmitter(s): Glutamate; Gaba;
Simulation Environment: PGENESIS; GENESIS;
Model Concept(s): Oscillations; Methods; Detailed Neuronal Models; Extracellular Fields;
Implementer(s): Crone, J ; Vindiola, MM ; Yu, AB ; Boothe, DL ; Beeman, Dave; Oie, KS ; Franaszczuk, PJ ; Anderson, WS ; Kudela, Pawel ; Traub, Roger D [rtraub at us.ibm.com];
Search NeuronDB for information about:  Thalamus reticular nucleus GABA cell; Neocortex L5/6 pyramidal GLU cell; Neocortex L2/3 pyramidal GLU cell; GabaA; AMPA; NMDA; I Sodium; I Calcium; I Potassium; Gaba; Glutamate;
// genesis

// synapticprobsnew.g is based on hardcoded probabilities baked into x_x
// connection files. These probabilities are different from those seen in
// synapticprobsTraub.g, and are in general much smaller.

//P23RSa spatial connection scales

// float inhibitorytargetscale = 1.0 // now defined in Neocortex.g

float P23RSdecayrate, P23RSmaxwgt, P23RSminwgt, P23RSbasewgt

P23RSdecayrate = 10000 // 1/(100e-6) m^-1
P23RSbasewgt = 1.0
P23RSminwgt = {0.0 + {excitatoryweightoffset}}
P23RSmaxwgt = {{{P23RSbasewgt}*{excitatoryweightscale}} + {excitatoryweightoffset}}

float P23RSa_P23RSa_prob = 0.02778
float P23RSa_P23RSb_prob = 0.02778
float P23RSa_P23RSc_prob = 0.02778
float P23RSa_P23RSd_prob = 0.02778
float P23RSa_B23FS_prob = {0.042*{inhibitorytargetscale}}
float P23RSa_P5IBa_prob = 0.12500
float P23RSa_P5IBb_prob = 0.12500
float P23RSa_P5IBc_prob = 0.12500
float P23RSa_P5IBd_prob = 0.12500
float P23RSa_B5FS_prob = {0.042*{inhibitorytargetscaleCross}}
float P23RSa_P6RSa_prob = 0.12500
float P23RSa_P6RSb_prob = 0.12500
float P23RSa_P6RSc_prob = 0.12500
float P23RSa_P6RSd_prob = 0.12500
float P23RSa_C23FS_prob = {0.042*{inhibitorytargetscale}}
float P23RSa_C5FS_prob = {0.042*{inhibitorytargetscaleCross}}
float P23RSa_ST4RS_prob = 0.042
float P23RSa_I23LTS_prob = {0.042*{inhibitorytargetscale}}
float P23RSa_I5LTS_prob = {0.042*{inhibitorytargetscaleCross}}
float P23RSa_P23FRBa_prob = 0.02778
float P23RSa_P5RSa_prob = 0.12500

//P23RSb spatial connection scales

float P23RSdecayrate, P23RSmaxwgt, P23RSminwgt, P23RSbasewgt

P23RSdecayrate = 10000 // 1/(100e-6) m^-1
P23RSbasewgt = 1.0
P23RSminwgt = {0.0 + {excitatoryweightoffset}}
P23RSmaxwgt = {{{P23RSbasewgt}*{excitatoryweightscale}} + {excitatoryweightoffset}}

float P23RSb_P23RSa_prob = 0.02778
float P23RSb_P23RSb_prob = 0.02778
float P23RSb_P23RSc_prob = 0.02778
float P23RSb_P23RSd_prob = 0.02778
float P23RSb_B23FS_prob = {0.042*{inhibitorytargetscale}}
float P23RSb_P5IBa_prob = 0.12500
float P23RSb_P5IBb_prob = 0.12500
float P23RSb_P5IBc_prob = 0.12500
float P23RSb_P5IBd_prob = 0.12500
float P23RSb_B5FS_prob = {0.042*{inhibitorytargetscaleCross}}
float P23RSb_P6RSa_prob = 0.12500
float P23RSb_P6RSb_prob = 0.12500
float P23RSb_P6RSc_prob = 0.12500
float P23RSb_P6RSd_prob = 0.12500
float P23RSb_C23FS_prob = {0.042*{inhibitorytargetscale}}
float P23RSb_C5FS_prob = {0.042*{inhibitorytargetscaleCross}}
float P23RSb_ST4RS_prob = 0.042
float P23RSb_I23LTS_prob = {0.042*{inhibitorytargetscale}}
float P23RSb_I5LTS_prob = {0.042*{inhibitorytargetscaleCross}}
float P23RSb_P23FRBa_prob = 0.02778
float P23RSb_P5RSa_prob = 0.12500

//P23RSc spatial connection scales

float P23RSdecayrate, P23RSmaxwgt, P23RSminwgt, P23RSbasewgt

P23RSdecayrate = 10000 // 1/(100e-6) m^-1
P23RSbasewgt = 1.0
P23RSminwgt = {0.0 + {excitatoryweightoffset}}
P23RSmaxwgt = {{{P23RSbasewgt}*{excitatoryweightscale}} + {excitatoryweightoffset}}

float P23RSc_P23RSa_prob = 0.02778
float P23RSc_P23RSb_prob = 0.02778
float P23RSc_P23RSc_prob = 0.02778
float P23RSc_P23RSd_prob = 0.02778
float P23RSc_B23FS_prob = {0.042*{inhibitorytargetscale}}
float P23RSc_P5IBa_prob = 0.12500
float P23RSc_P5IBb_prob = 0.12500
float P23RSc_P5IBc_prob = 0.12500
float P23RSc_P5IBd_prob = 0.12500
float P23RSc_B5FS_prob = {0.042*{inhibitorytargetscaleCross}}
float P23RSc_P6RSa_prob = 0.12500
float P23RSc_P6RSb_prob = 0.12500
float P23RSc_P6RSc_prob = 0.12500
float P23RSc_P6RSd_prob = 0.12500
float P23RSc_C23FS_prob = {0.042*{inhibitorytargetscale}}
float P23RSc_C5FS_prob = {0.042*{inhibitorytargetscaleCross}}
float P23RSc_ST4RS_prob = 0.042
float P23RSc_I23LTS_prob = {0.042*{inhibitorytargetscale}}
float P23RSc_I5LTS_prob = {0.042*{inhibitorytargetscaleCross}}
float P23RSc_P23FRBa_prob = 0.02778
float P23RSc_P5RSa_prob = 0.12500

//P23RSd spatial connection scales

float P23RSdecayrate, P23RSmaxwgt, P23RSminwgt, P23RSbasewgt

P23RSdecayrate = 10000 // 1/(100e-6) m^-1
P23RSbasewgt = 1.0
P23RSminwgt = {0.0 + {excitatoryweightoffset}}
P23RSmaxwgt = {{{P23RSbasewgt}*{excitatoryweightscale}} + {excitatoryweightoffset}}

float P23RSd_P23RSa_prob = 0.02778
float P23RSd_P23RSb_prob = 0.02778
float P23RSd_P23RSc_prob = 0.02778
float P23RSd_P23RSd_prob = 0.02778
float P23RSd_B23FS_prob = {0.042*{inhibitorytargetscale}}
float P23RSd_P5IBa_prob = 0.12500
float P23RSd_P5IBb_prob = 0.12500
float P23RSd_P5IBc_prob = 0.12500
float P23RSd_P5IBd_prob = 0.12500
float P23RSd_B5FS_prob = {0.042*{inhibitorytargetscaleCross}}
float P23RSd_P6RSa_prob = 0.12500
float P23RSd_P6RSb_prob = 0.12500
float P23RSd_P6RSc_prob = 0.12500
float P23RSd_P6RSd_prob = 0.12500
float P23RSd_C23FS_prob = {0.042*{inhibitorytargetscale}}
float P23RSd_C5FS_prob = {0.042*{inhibitorytargetscaleCross}}
float P23RSd_ST4RS_prob = 0.042
float P23RSd_I23LTS_prob = {0.042*{inhibitorytargetscale}}
float P23RSd_I5LTS_prob = {0.042*{inhibitorytargetscaleCross}}
float P23RSd_P23FRBa_prob = 0.02778
float P23RSd_P5RSa_prob = 0.12500

//B23FS spatial connection scales

float B23FSdecayrate, B23FSmaxwgt, B23FSminwgt, B23FSbasewgt

B23FSdecayrate = 10000 // 1/(100e-6) m^-1
B23FSbasewgt = 1.0
B23FSminwgt = {0.0 + {inhibitoryweightoffset}}
B23FSmaxwgt = {{{B23FSbasewgt}*{inhibitoryweightscale}} + {inhibitoryweightoffset}}

float B23FS_P23RSa_prob = 0.091
float B23FS_P23RSb_prob = 0.091
float B23FS_P23RSc_prob = 0.091
float B23FS_P23RSd_prob = 0.091
float B23FS_B23FS_prob = {0.042*{inhibitorytargetscale}}
float B23FS_C23FS_prob = {0.042*{inhibitorytargetscale}}
float B23FS_ST4RS_prob = 0.200
float B23FS_I23LTS_prob = {0.042*{inhibitorytargetscale}}
float B23FS_P23FRBa_prob = 0.091

//P5IBa spatial connection scales

float P5IBdecayrate, P5IBmaxwgt, P5IBminwgt, P5IBbasewgt

P5IBdecayrate = 10000 // 1/(100e-6) m^-1
P5IBbasewgt = 1.0
P5IBminwgt = {0.0 + {excitatoryweightoffset}}
P5IBmaxwgt = {{{P5IBbasewgt}*{excitatoryweightscale}} + {excitatoryweightoffset}}

float P5IBa_P23RSa_prob = 0.07692
float P5IBa_P23RSb_prob = 0.07692
float P5IBa_P23RSc_prob = 0.07692
float P5IBa_P23RSd_prob = 0.07692
float P5IBa_B23FS_prob = {0.042*{inhibitorytargetscaleCross}}
float P5IBa_P5IBa_prob = 0.02174
float P5IBa_P5IBb_prob = 0.02174
float P5IBa_P5IBc_prob = 0.02174
float P5IBa_P5IBd_prob = 0.02174
float P5IBa_B5FS_prob = {0.042*{inhibitorytargetscale}}
float P5IBa_P6RSa_prob = 0.02326
float P5IBa_P6RSb_prob = 0.02326
float P5IBa_P6RSc_prob = 0.02326
float P5IBa_P6RSd_prob = 0.02326
float P5IBa_C23FS_prob = {0.042*{inhibitorytargetscaleCross}}
float P5IBa_C5FS_prob = {0.042*{inhibitorytargetscale}}
float P5IBa_ST4RS_prob = 0.042
float P5IBa_I23LTS_prob = {0.042*{inhibitorytargetscaleCross}}
float P5IBa_I5LTS_prob = {0.042*{inhibitorytargetscale}}
float P5IBa_P23FRBa_prob = 0.07692
float P5IBa_P5RSa_prob = 0.02174

//P5IBb spatial connection scales

float P5IBdecayrate, P5IBmaxwgt, P5IBminwgt, P5IBbasewgt

P5IBdecayrate = 10000 // 1/(100e-6) m^-1
P5IBbasewgt = 1.0
P5IBminwgt = {0.0 + {excitatoryweightoffset}}
P5IBmaxwgt = {{{P5IBbasewgt}*{excitatoryweightscale}} + {excitatoryweightoffset}}

float P5IBb_P23RSa_prob = 0.07692
float P5IBb_P23RSb_prob = 0.07692
float P5IBb_P23RSc_prob = 0.07692
float P5IBb_P23RSd_prob = 0.07692
float P5IBb_B23FS_prob = {0.042*{inhibitorytargetscale}}
float P5IBb_P5IBa_prob = 0.02174
float P5IBb_P5IBb_prob = 0.02174
float P5IBb_P5IBc_prob = 0.02174
float P5IBb_P5IBd_prob = 0.02174
float P5IBb_B5FS_prob = {0.042*{inhibitorytargetscale}}
float P5IBb_P6RSa_prob = 0.02326
float P5IBb_P6RSb_prob = 0.02326
float P5IBb_P6RSc_prob = 0.02326
float P5IBb_P6RSd_prob = 0.02326
float P5IBb_C23FS_prob = {0.042*{inhibitorytargetscaleCross}}
float P5IBb_C5FS_prob = {0.042*{inhibitorytargetscale}}
float P5IBb_ST4RS_prob = 0.042
float P5IBb_I23LTS_prob = {0.042*{inhibitorytargetscaleCross}}
float P5IBb_I5LTS_prob = {0.042*{inhibitorytargetscale}}
float P5IBb_P23FRBa_prob = 0.07692
float P5IBb_P5RSa_prob = 0.02174

//P5IBc spatial connection scales

float P5IBdecayrate, P5IBmaxwgt, P5IBminwgt, P5IBbasewgt

P5IBdecayrate = 10000 // 1/(100e-6) m^-1
P5IBbasewgt = 1.0
P5IBminwgt = {0.0 + {excitatoryweightoffset}}
P5IBmaxwgt = {{{P5IBbasewgt}*{excitatoryweightscale}} + {excitatoryweightoffset}}

float P5IBc_P23RSa_prob = 0.07692
float P5IBc_P23RSb_prob = 0.07692
float P5IBc_P23RSc_prob = 0.07692
float P5IBc_P23RSd_prob = 0.07692
float P5IBc_B23FS_prob = {0.042*{inhibitorytargetscaleCross}}
float P5IBc_P5IBa_prob = 0.02174
float P5IBc_P5IBb_prob = 0.02174
float P5IBc_P5IBc_prob = 0.02174
float P5IBc_P5IBd_prob = 0.02174
float P5IBc_B5FS_prob = {0.042*{inhibitorytargetscale}}
float P5IBc_P6RSa_prob = 0.02326
float P5IBc_P6RSb_prob = 0.02326
float P5IBc_P6RSc_prob = 0.02326
float P5IBc_P6RSd_prob = 0.02326
float P5IBc_C23FS_prob = {0.042*{inhibitorytargetscaleCross}}
float P5IBc_C5FS_prob = {0.042*{inhibitorytargetscale}}
float P5IBc_ST4RS_prob = 0.042
float P5IBc_I23LTS_prob = {0.042*{inhibitorytargetscaleCross}}
float P5IBc_I5LTS_prob = {0.042*{inhibitorytargetscale}}
float P5IBc_P23FRBa_prob = 0.07692
float P5IBc_P5RSa_prob = 0.02174

//P5IBd spatial connection scales

float P5IBdecayrate, P5IBmaxwgt, P5IBminwgt, P5IBbasewgt

P5IBdecayrate = 10000 // 1/(100e-6) m^-1
P5IBbasewgt = 1.0
P5IBminwgt = {0.0 + {excitatoryweightoffset}}
P5IBmaxwgt = {{{P5IBbasewgt}*{excitatoryweightscale}} + {excitatoryweightoffset}}

float P5IBd_P23RSa_prob = 0.07692
float P5IBd_P23RSb_prob = 0.07692
float P5IBd_P23RSc_prob = 0.07692
float P5IBd_P23RSd_prob = 0.07692
float P5IBd_B23FS_prob = {0.042*{inhibitorytargetscaleCross}}
float P5IBd_P5IBa_prob = 0.02174
float P5IBd_P5IBb_prob = 0.02174
float P5IBd_P5IBc_prob = 0.02174
float P5IBd_P5IBd_prob = 0.02174
float P5IBd_B5FS_prob = {0.042*{inhibitorytargetscale}}
float P5IBd_P6RSa_prob = 0.02326
float P5IBd_P6RSb_prob = 0.02326
float P5IBd_P6RSc_prob = 0.02326
float P5IBd_P6RSd_prob = 0.02326
float P5IBd_C23FS_prob = {0.042*{inhibitorytargetscaleCross}}
float P5IBd_C5FS_prob = {0.042*{inhibitorytargetscale}}
float P5IBd_ST4RS_prob = 0.042
float P5IBd_I23LTS_prob = {0.042*{inhibitorytargetscaleCross}}
float P5IBd_I5LTS_prob = {0.042*{inhibitorytargetscale}}
float P5IBd_P23FRBa_prob = 0.07692
float P5IBd_P5RSa_prob = 0.02174

//B5FS spatial connection scales

float B5FSdecayrate, B5FSmaxwgt, B5FSminwgt, B5FSbasewgt

B5FSdecayrate = 10000 // 1/(100e-6) m^-1
B5FSbasewgt = 1.0
B5FSminwgt = {0.0 + {inhibitoryweightoffset}}
B5FSmaxwgt = {{{B5FSbasewgt}*{inhibitoryweightscale}} + {inhibitoryweightoffset}}

float B5FS_P5IBa_prob = 0.12500
float B5FS_P5IBb_prob = 0.12500
float B5FS_P5IBc_prob = 0.12500
float B5FS_P5IBd_prob = 0.12500
float B5FS_B5FS_prob = {0.042*{inhibitorytargetscale}}
float B5FS_P6RSa_prob = 0.14300
float B5FS_P6RSb_prob = 0.14300
float B5FS_P6RSc_prob = 0.14300
float B5FS_P6RSd_prob = 0.14300
float B5FS_C5FS_prob = {0.042*{inhibitorytargetscale}}
float B5FS_ST4RS_prob = 0.200
float B5FS_I5LTS_prob = {0.042*{inhibitorytargetscale}}
float B5FS_P5RSa_prob = 0.12500

//P6RSa spatial connection scales

float P6RSdecayrate, P6RSmaxwgt, P6RSminwgt, P6RSbasewgt

P6RSdecayrate = 10000 // 1/(100e-6) m^-1
P6RSbasewgt = 1.0
P6RSminwgt = {0.0 + {excitatoryweightoffset}}
P6RSmaxwgt = {{{P6RSbasewgt}*{excitatoryweightscale}} + {excitatoryweightoffset}}

float P6RSa_P23RSa_prob = 0.25000
float P6RSa_P23RSb_prob = 0.25000
float P6RSa_P23RSc_prob = 0.25000
float P6RSa_P23RSd_prob = 0.25000
float P6RSa_B23FS_prob = {0.042*{inhibitorytargetscale6}}
float P6RSa_P5IBa_prob = 0.02174
float P6RSa_P5IBb_prob = 0.02174
float P6RSa_P5IBc_prob = 0.02174
float P6RSa_P5IBd_prob = 0.02174
float P6RSa_B5FS_prob = {0.042*{inhibitorytargetscale6}}
float P6RSa_P6RSa_prob = 0.02326
float P6RSa_P6RSb_prob = 0.02326
float P6RSa_P6RSc_prob = 0.02326
float P6RSa_P6RSd_prob = 0.02326
float P6RSa_C23FS_prob = {0.042*{inhibitorytargetscale6}}
float P6RSa_C5FS_prob = {0.042*{inhibitorytargetscale6}}
float P6RSa_ST4RS_prob = 0.042
float P6RSa_I23LTS_prob = {0.042*{inhibitorytargetscale6}}
float P6RSa_I5LTS_prob = {0.042*{inhibitorytargetscale6}}
float P6RSa_TCR_prob = 0.01111
float P6RSa_nRT_prob = 0.08333
float P6RSa_P23FRBa_prob = 0.25000
float P6RSa_P5RSa_prob = 0.02174

//P6RSb spatial connection scales

float P6RSdecayrate, P6RSmaxwgt, P6RSminwgt, P6RSbasewgt

P6RSdecayrate = 10000 // 1/(100e-6) m^-1
P6RSbasewgt = 1.0
P6RSminwgt = {0.0 + {excitatoryweightoffset}}
P6RSmaxwgt = {{{P6RSbasewgt}*{excitatoryweightscale}} + {excitatoryweightoffset}}

float P6RSb_P23RSa_prob = 0.25000
float P6RSb_P23RSb_prob = 0.25000
float P6RSb_P23RSc_prob = 0.25000
float P6RSb_P23RSd_prob = 0.25000
float P6RSb_B23FS_prob = {0.042*{inhibitorytargetscale6}}
float P6RSb_P5IBa_prob = 0.02174
float P6RSb_P5IBb_prob = 0.02174
float P6RSb_P5IBc_prob = 0.02174
float P6RSb_P5IBd_prob = 0.02174
float P6RSb_B5FS_prob = {0.042*{inhibitorytargetscale6}}
float P6RSb_P6RSa_prob = 0.02326
float P6RSb_P6RSb_prob = 0.02326
float P6RSb_P6RSc_prob = 0.02326
float P6RSb_P6RSd_prob = 0.02326
float P6RSb_C23FS_prob = {0.042*{inhibitorytargetscale6}}
float P6RSb_C5FS_prob = {0.042*{inhibitorytargetscale6}}
float P6RSb_ST4RS_prob = 0.042
float P6RSb_I23LTS_prob = {0.042*{inhibitorytargetscale6}}
float P6RSb_I5LTS_prob = {0.042*{inhibitorytargetscale6}}
float P6RSb_TCR_prob = 0.01111
float P6RSb_nRT_prob = 0.08333
float P6RSb_P23FRBa_prob = 0.25000
float P6RSb_P5RSa_prob = 0.02174

//P6RSc spatial connection scales

float P6RSdecayrate, P6RSmaxwgt, P6RSminwgt, P6RSbasewgt

P6RSdecayrate = 10000 // 1/(100e-6) m^-1
P6RSbasewgt = 1.0
P6RSminwgt = {0.0 + {excitatoryweightoffset}}
P6RSmaxwgt = {{{P6RSbasewgt}*{excitatoryweightscale}} + {excitatoryweightoffset}}

float P6RSc_P23RSa_prob = 0.25000
float P6RSc_P23RSb_prob = 0.25000
float P6RSc_P23RSc_prob = 0.25000
float P6RSc_P23RSd_prob = 0.25000
float P6RSc_B23FS_prob = {0.042*{inhibitorytargetscale6}}
float P6RSc_P5IBa_prob = 0.02174
float P6RSc_P5IBb_prob = 0.02174
float P6RSc_P5IBc_prob = 0.02174
float P6RSc_P5IBd_prob = 0.02174
float P6RSc_B5FS_prob = {0.042*{inhibitorytargetscale6}}
float P6RSc_P6RSa_prob = 0.02326
float P6RSc_P6RSb_prob = 0.02326
float P6RSc_P6RSc_prob = 0.02326
float P6RSc_P6RSd_prob = 0.02326
float P6RSc_C23FS_prob = {0.042*{inhibitorytargetscale6}}
float P6RSc_C5FS_prob = {0.042*{inhibitorytargetscale6}}
float P6RSc_ST4RS_prob = 0.042
float P6RSc_I23LTS_prob = {0.042*{inhibitorytargetscale6}}
float P6RSc_I5LTS_prob = {0.042*{inhibitorytargetscale6}}
float P6RSc_TCR_prob = 0.01111
float P6RSc_nRT_prob = 0.08333
float P6RSc_P23FRBa_prob = 0.25000
float P6RSc_P5RSa_prob = 0.02174

//P6RSd spatial connection scales

float P6RSdecayrate, P6RSmaxwgt, P6RSminwgt, P6RSbasewgt

P6RSdecayrate = 10000 // 1/(100e-6) m^-1
P6RSbasewgt = 1.0
P6RSminwgt = {0.0 + {excitatoryweightoffset}}
P6RSmaxwgt = {{{P6RSbasewgt}*{excitatoryweightscale}} + {excitatoryweightoffset}}

float P6RSd_P23RSa_prob = 0.25000
float P6RSd_P23RSb_prob = 0.25000
float P6RSd_P23RSc_prob = 0.25000
float P6RSd_P23RSd_prob = 0.25000
float P6RSd_B23FS_prob = {0.042*{inhibitorytargetscale6}}
float P6RSd_P5IBa_prob = 0.02174
float P6RSd_P5IBb_prob = 0.02174
float P6RSd_P5IBc_prob = 0.02174
float P6RSd_P5IBd_prob = 0.02174
float P6RSd_B5FS_prob = {0.042*{inhibitorytargetscale6}}
float P6RSd_P6RSa_prob = 0.02326
float P6RSd_P6RSb_prob = 0.02326
float P6RSd_P6RSc_prob = 0.02326
float P6RSd_P6RSd_prob = 0.02326
float P6RSd_C23FS_prob = {0.042*{inhibitorytargetscale6}}
float P6RSd_C5FS_prob = {0.042*{inhibitorytargetscale6}}
float P6RSd_ST4RS_prob = 0.042
float P6RSd_I23LTS_prob = {0.042*{inhibitorytargetscale6}}
float P6RSd_I5LTS_prob = {0.042*{inhibitorytargetscale6}}
float P6RSd_TCR_prob = 0.01111
float P6RSd_nRT_prob = 0.08333
float P6RSd_P23FRBa_prob = 0.25000
float P6RSd_P5RSa_prob = 0.02174

//C23FS spatial connection scales

float C23FSdecayrate, C23FSmaxwgt, C23FSminwgt, C23FSbasewgt

C23FSdecayrate = 10000 // 1/(100e-6) m^-1
C23FSbasewgt = 1.0
C23FSminwgt = {0.0 + {inhibitoryweightoffset}}
C23FSmaxwgt = {{{C23FSbasewgt}*{inhibitoryweightscale}} + {inhibitoryweightoffset}}

float C23FS_P23RSa_prob = 1.0
float C23FS_P23RSb_prob = 1.0
float C23FS_P23RSc_prob = 1.0
float C23FS_P23RSd_prob = 1.0
float C23FS_P5IBa_prob = 1.0
float C23FS_P5IBb_prob = 1.0
float C23FS_P5IBc_prob = 1.0
float C23FS_P5IBd_prob = 1.0
float C23FS_P6RSa_prob = 1.0
float C23FS_P6RSb_prob = 1.0
float C23FS_P6RSc_prob = 1.0
float C23FS_P6RSd_prob = 1.0
float C23FS_ST4RS_prob = 1.0
float C23FS_P23FRBa_prob = 1.0
float C23FS_P5RSa_prob = 1.0

//C5FS spatial connection scales

float C5FSdecayrate, C5FSmaxwgt, C5FSminwgt, C5FSbasewgt

C5FSdecayrate = 10000 // 1/(100e-6) m^-1
C5FSbasewgt = 1.0
C5FSminwgt = {0.0 + {inhibitoryweightoffset}}
C5FSmaxwgt = {{{C5FSbasewgt}*{inhibitoryweightscale}} + {inhibitoryweightoffset}}

float C5FS_P23RSa_prob = 1.0
float C5FS_P23RSb_prob = 1.0
float C5FS_P23RSc_prob = 1.0
float C5FS_P23RSd_prob = 1.0
float C5FS_P5IBa_prob = 1.0
float C5FS_P5IBb_prob = 1.0
float C5FS_P5IBc_prob = 1.0
float C5FS_P5IBd_prob = 1.0
float C5FS_P6RSa_prob = 1.0
float C5FS_P6RSb_prob = 1.0
float C5FS_P6RSc_prob = 1.0
float C5FS_P6RSd_prob = 1.0
float C5FS_ST4RS_prob = 1.0
float C5FS_P23FRBa_prob = 1.0
float C5FS_P5RSa_prob = 1.0

//ST4RS spatial connection scales

float ST4RSdecayrate, ST4RSmaxwgt, ST4RSminwgt, ST4RSbasewgt

ST4RSdecayrate = 10000 // 1/(100e-6) m^-1
ST4RSbasewgt = 1.0
ST4RSminwgt = {0.0 + {excitatoryweightoffset}}
ST4RSmaxwgt = {{{ST4RSbasewgt}*{excitatoryweightscale}} + {excitatoryweightoffset}}

float ST4RS_P23RSa_prob = 0.04167
float ST4RS_P23RSb_prob = 0.04167
float ST4RS_P23RSc_prob = 0.04167
float ST4RS_P23RSd_prob = 0.04167
float ST4RS_B23FS_prob = {0.042*{inhibitorytargetscale}}
float ST4RS_P5IBa_prob = 0.08333
float ST4RS_P5IBb_prob = 0.08333
float ST4RS_P5IBc_prob = 0.08333
float ST4RS_P5IBd_prob = 0.08333
float ST4RS_B5FS_prob = {0.042*{inhibitorytargetscale}}
float ST4RS_P6RSa_prob = 0.200
float ST4RS_P6RSb_prob = 0.200
float ST4RS_P6RSc_prob = 0.200
float ST4RS_P6RSd_prob = 0.200
float ST4RS_C23FS_prob = {0.042*{inhibitorytargetscale}}
float ST4RS_C5FS_prob = {0.042*{inhibitorytargetscale}}
float ST4RS_ST4RS_prob = 0.042
float ST4RS_I23LTS_prob = {0.042*{inhibitorytargetscale}}
float ST4RS_I5LTS_prob = {0.042*{inhibitorytargetscale}}
float ST4RS_P23FRBa_prob = 0.04167
float ST4RS_P5RSa_prob = 0.08333

//I23LTS spatial connection scales

float I23LTSdecayrate, I23LTSmaxwgt, I23LTSminwgt, I23LTSbasewgt

I23LTSdecayrate = 10000 // 1/(100e-6) m^-1 boothe changed from 10000
I23LTSbasewgt = 1.0
I23LTSminwgt = {0.0 + {inhibitoryweightoffset}}
I23LTSmaxwgt = {{{I23LTSbasewgt}*{inhibitoryweightscale}} + {inhibitoryweightoffset}}

float I23LTS_P23RSa_prob = 0.01887
float I23LTS_P23RSb_prob = 0.01887
float I23LTS_P23RSc_prob = 0.01887
float I23LTS_P23RSd_prob = 0.01887
float I23LTS_B23FS_prob = {0.02500*{inhibitorytargetscale}}
float I23LTS_P5IBa_prob = 0.02500
float I23LTS_P5IBb_prob = 0.02500
float I23LTS_P5IBc_prob = 0.02500
float I23LTS_P5IBd_prob = 0.02500
float I23LTS_B5FS_prob = {0.04200*{inhibitorytargetscaleCross}}
float I23LTS_P6RSa_prob = 0.03448
float I23LTS_P6RSb_prob = 0.03448
float I23LTS_P6RSc_prob = 0.03448
float I23LTS_P6RSd_prob = 0.03448
float I23LTS_C23FS_prob = {0.02500*{inhibitorytargetscale}}
float I23LTS_C5FS_prob = {0.04200*{inhibitorytargetscaleCross}}
float I23LTS_ST4RS_prob = 0.02500
float I23LTS_I23LTS_prob = {0.02500*{inhibitorytargetscale}}
float I23LTS_I5LTS_prob = {0.04200*{inhibitorytargetscaleCross}}
float I23LTS_P23FRBa_prob = 0.01887
float I23LTS_P5RSa_prob = 0.02500

//I5LTS spatial connection scales

float I5LTSdecayrate, I5LTSmaxwgt, I5LTSminwgt, I5LTSbasewgt

I5LTSdecayrate = 10000 // 1/(100e-6) m^-1  boothe changed from 10000
I5LTSbasewgt = 1.0
I5LTSminwgt = {0.0 + {inhibitoryweightoffset}}
I5LTSmaxwgt = {{{I5LTSbasewgt}*{inhibitoryweightscale}} + {inhibitoryweightoffset}}

float I5LTS_P23RSa_prob = 0.01887
float I5LTS_P23RSb_prob = 0.01887
float I5LTS_P23RSc_prob = 0.01887
float I5LTS_P23RSd_prob = 0.01887
float I5LTS_B23FS_prob = {0.02500*{inhibitorytargetscaleCross}}
float I5LTS_P5IBa_prob = 0.02500
float I5LTS_P5IBb_prob = 0.02500
float I5LTS_P5IBc_prob = 0.02500
float I5LTS_P5IBd_prob = 0.02500
float I5LTS_B5FS_prob = {0.04200*{inhibitorytargetscale}}
float I5LTS_P6RSa_prob = 0.03448
float I5LTS_P6RSb_prob = 0.03448
float I5LTS_P6RSc_prob = 0.03448
float I5LTS_P6RSd_prob = 0.03448
float I5LTS_C23FS_prob = {0.02500*{inhibitorytargetscaleCross}}
float I5LTS_C5FS_prob = {0.04200*{inhibitorytargetscale}}
float I5LTS_ST4RS_prob = 0.02500
float I5LTS_I23LTS_prob = {0.02500*{inhibitorytargetscaleCross}}
float I5LTS_I5LTS_prob = {0.04200*{inhibitorytargetscale}}
float I5LTS_P23FRBa_prob = 0.01887
float I5LTS_P5RSa_prob = 0.02500

//TCR spatial connection scales

float TCRdecayrate, TCRmaxwgt, TCRminwgt, TCRbasewgt

TCRdecayrate = 10000 // 1/(100e-6) m^-1
TCRbasewgt = 1.0
TCRminwgt = {0.0 + {excitatoryweightoffset}}
TCRmaxwgt = {{{TCRbasewgt}*{excitatoryweightscale}} + {excitatoryweightoffset}}

float TCR_P23RSa_prob = 0.04167
float TCR_P23RSb_prob = 0.04167
float TCR_P23RSc_prob = 0.04167
float TCR_P23RSd_prob = 0.04167
float TCR_B23FS_prob = {0.08333*{inhibitorytargetscale}}
float TCR_P5IBa_prob = 0.11111
float TCR_P5IBb_prob = 0.11111
float TCR_P5IBc_prob = 0.11111
float TCR_P5IBd_prob = 0.11111
float TCR_B5FS_prob = {0.08333*{inhibitorytargetscale}}
float TCR_P6RSa_prob = 0.20000
float TCR_P6RSb_prob = 0.20000
float TCR_P6RSc_prob = 0.20000
float TCR_P6RSd_prob = 0.20000
float TCR_C23FS_prob = {0.08333*{inhibitorytargetscale}}
float TCR_C5FS_prob = {0.08333*{inhibitorytargetscale}}
float TCR_ST4RS_prob = 0.01923
float TCR_nRT_prob = 0.042
float TCR_P23FRBa_prob = 0.04167
float TCR_P5RSa_prob = 0.11111

//nRT spatial connection scales

float nRTdecayrate, nRTmaxwgt, nRTminwgt, nRTbasewgt

nRTdecayrate = 10000 // 1/(100e-6) m^-1
nRTbasewgt = 1.0
nRTminwgt = {0.0 + {inhibitoryweightoffset}}
nRTmaxwgt = {{{nRTbasewgt}*{inhibitoryweightscale}} + {inhibitoryweightoffset}}

float nRT_TCR_prob = 0.01111
float nRT_nRT_prob = 0.02083

//P23FRBa spatial connection scales

float P23FRBdecayrate, P23FRBmaxwgt, P23FRBminwgt, P23FRBbasewgt

P23FRBdecayrate = 10000 // 1/(100e-6) m^-1
P23FRBbasewgt = 1.0
P23FRBminwgt = {0.0 + {excitatoryweightoffset}}
P23FRBmaxwgt = {{{P23FRBbasewgt}*{excitatoryweightscale}} + {excitatoryweightoffset}}

float P23FRBa_P23RSa_prob = 0.02778
float P23FRBa_P23RSb_prob = 0.02778
float P23FRBa_P23RSc_prob = 0.02778
float P23FRBa_P23RSd_prob = 0.02778
float P23FRBa_B23FS_prob = {0.042*{inhibitorytargetscale}}
float P23FRBa_P5IBa_prob = 0.12500
float P23FRBa_P5IBb_prob = 0.12500
float P23FRBa_P5IBc_prob = 0.12500
float P23FRBa_P5IBd_prob = 0.12500
float P23FRBa_B5FS_prob = {0.042*{inhibitorytargetscaleCross}}
float P23FRBa_P6RSa_prob = 0.12500
float P23FRBa_P6RSb_prob = 0.12500
float P23FRBa_P6RSc_prob = 0.12500
float P23FRBa_P6RSd_prob = 0.12500
float P23FRBa_C23FS_prob = {0.042*{inhibitorytargetscale}}
float P23FRBa_C5FS_prob = {0.042*{inhibitorytargetscaleCross}}
float P23FRBa_ST4RS_prob = 0.042
float P23FRBa_I23LTS_prob = {0.042*{inhibitorytargetscale}}
float P23FRBa_I5LTS_prob = {0.042*{inhibitorytargetscaleCross}}
float P23FRBa_P23FRBa_prob = 0.02778
float P23FRBa_P5RSa_prob = 0.12500

//P5RSa spatial connection scales

float P5RSdecayrate, P5RSmaxwgt, P5RSminwgt, P5RSbasewgt

P5RSdecayrate = 10000 // 1/(100e-6) m^-1
P5RSbasewgt = 1.0
P5RSminwgt = {0.0 + {excitatoryweightoffset}}
P5RSmaxwgt = {{{P5RSbasewgt}*{excitatoryweightscale}} + {excitatoryweightoffset}}

float P5RSa_P23RSa_prob = 0.07692
float P5RSa_P23RSb_prob = 0.07692
float P5RSa_P23RSc_prob = 0.07692
float P5RSa_P23RSd_prob = 0.07692
float P5RSa_B23FS_prob = {0.042*{inhibitorytargetscaleCross}}
float P5RSa_P5IBa_prob = 0.02174
float P5RSa_P5IBb_prob = 0.02174
float P5RSa_P5IBc_prob = 0.02174
float P5RSa_P5IBd_prob = 0.02174
float P5RSa_B5FS_prob = {0.042*{inhibitorytargetscale}}
float P5RSa_P6RSa_prob = 0.02326
float P5RSa_P6RSb_prob = 0.02326
float P5RSa_P6RSc_prob = 0.02326
float P5RSa_P6RSd_prob = 0.02326
float P5RSa_C23FS_prob = {0.042*{inhibitorytargetscaleCross}}
float P5RSa_C5FS_prob = {0.042*{inhibitorytargetscale}}
float P5RSa_ST4RS_prob = 0.042
float P5RSa_I23LTS_prob = {0.042*{inhibitorytargetscaleCross}}
float P5RSa_I5LTS_prob = {0.042*{inhibitorytargetscale}}
float P5RSa_P23FRBa_prob = 0.07692
float P5RSa_P5RSa_prob = 0.02174

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