These scripts were used to model a patch of layer 2/3 primary auditory cortex,
making use of the the improvements to PGENESIS by Crone, et al. (2019).
This single layer model contains a 48 x 48 grid of pyramidal cells (PCs)
and a 24 x 24 grid of basket cells (BCs). The reduced PC models have 17
compartments with dimensions and passive properties that were fit to human
cortical PC reconstructions. This parallel version of the simulation was used
by Beeman, et al. (2019) to understand the effects of inhibition of PCs by
BCs on auditory evoked potentials.
References:
1 .
Beeman D, Yu A, Crone J (2019) Studying evoked potentials in large cortical
networks with PGENESIS 2.4 BMC Neuroscience 20 Suppl 1:P46
2 .
Crone JC, Vindiola MM, Yu AB, Boothe DL, Beeman D, Oie KS, Franaszczuk PJ (2019) Enabling Large-Scale Simulations With the GENESIS Neuronal Simulator Frontiers in Neuroinformatics 13:69
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