Entrainment and divisive inhibition in a neocortical neural mass model (Papasavvas et al 2020)

 Download zip file 
Help downloading and running models
Neural mass model of a neocortical microcircuit featuring one excitatory and two inhibitory populations. The inhibitory populations represent the soma-targeting (parvalbumin) and dendrite-targeting (somatostatin) interneurons. The model uses the Wilson-Cowan formalism and differentiates between the two inhibitory populations by the way they modulate the input-output function of the excitatory population (subtractive vs divisive inhibition, based on Wilson et al., Nature, 7411, 488, 343-348, 2012). The connectivity patterns between the populations follow the patterns reported in the primary visual cortex (Pfeffer et al., Nat Neurosci 16, 1068–1076, 2013). The model is used here to investigate the role of divisive inhibition during the entrainment of the microcircuit.
1 . Papasavvas CA, Trevelyan AJ, Kaiser M, Wang Y (2020) Divisive gain modulation enables flexible and rapid entrainment in a neocortical microcircuit model. J Neurophysiol 123:1133-1143 [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type: Neural mass;
Brain Region(s)/Organism: Neocortex;
Cell Type(s):
Gap Junctions:
Simulation Environment: MATLAB;
Model Concept(s): Contrast-gain control; Oscillations;
Implementer(s): Papasavvas, Christoforos [Christoforos.Papasavvas at newcastle.ac.uk];
Loading data, please wait...