CA3 hippocampal pyramidal neuron with voltage-clamp intrinsic conductance data (Traub et al 1991)

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Accession:266905
This is a third-party implementation of the model from Traub et al 1991; as of 2021, Google Scholar reports about 780 citation articles. This model was one of the first biophysical models of a hippocampal pyramidal neuron with realistic conductances and the conductance equations have been used as a starting point for many models since, particularly those examining calcium dynamics and bursting.
Reference:
1 . Traub RD, Wong RK, Miles R, Michelson H (1991) A model of a CA3 hippocampal pyramidal neuron incorporating voltage-clamp data on intrinsic conductances. J Neurophysiol 66:635-50 [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type: Dendrite;
Brain Region(s)/Organism: Hippocampus;
Cell Type(s): Hippocampus CA3 pyramidal GLU cell;
Channel(s): I Calcium; I A; I K,Ca; I Sodium; I K;
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment: NEURON;
Model Concept(s): Active Dendrites;
Implementer(s): Conde, James; Dewell, Richard Burkett [dewell at bcm.edu]; Gabbiani, F;
Search NeuronDB for information about:  Hippocampus CA3 pyramidal GLU cell; I A; I K; I K,Ca; I Sodium; I Calcium;
// hoc file generating Fig. 8.
// call as follows:
//  ./x86_64/special GenerateFig8.hoc -
//
figNumber = 8
load_file(1,"traub.hoc")
chdir("Traub_Figures/TraubFigure8")
load_file(1,"fig8.hoc")

chdir("../..")
printf("finished Figure 8 simulation\n")


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