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HH model of SCN neurons including a transient K+ channel (Bano-Otalora et al 2021)

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Accession:267183
This MATLAB code is associated with the paper "Daily electrical activity in the master circadian clock of a diurnal mammal" by Beatriz Bano-Otalora, Matthew J Moye, Timothy Brown, Robert J Lucas, Casey O Diekman, Mino DC Belle. eLife 2021; 10:e68719 DOI: https://doi.org/10.7554/eLife.68179 It simulates a Hodgkin-Huxley-type model of the electrical activity of suprachiasmatic nucleus (SCN) neurons in the diurnal rodent Rhabdomys pumilio. Model parameters were inferred from current-clamp recordings using data assimilation (DA) algorithms available at https://github.com/mattmoye/neuroDA
Reference:
1 . Bano-Otalora B, Moye MJ, Brown T, Lucas RJ, Diekman CO, Belle MDC (2021) Daily electrical activity in the master circadian clock of a diurnal mammal eLife
Model Information (Click on a link to find other models with that property)
Model Type: Neuron or other electrically excitable cell;
Brain Region(s)/Organism:
Cell Type(s): Suprachiasmatic nucleus (SCN) neuron;
Channel(s): I A; I Calcium; I Na,t; I K; I h; I K,leak; I Na, leak;
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment: MATLAB;
Model Concept(s): Action Potentials; Circadian Rhythms; Depolarization block; Parameter Fitting;
Implementer(s): Diekman, Casey O. [casey.o.diekman at njit.edu]; Moye, Matthew; Saghafi, Soheil;
Search NeuronDB for information about:  I Na,t; I A; I K; I K,leak; I h; I Calcium; I Na, leak;
 
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ModelDB_Bano-Otalora_and_Moye_etal_2021_eLife
                            
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