Depolarization Enhacement of Dendritic Spike Propagation (Bock et al 2022)

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Accession:267311
This model shows that small subthreshold depolarization of the soma powerfully enhances the propagation of dendritic spikes, through inactivation of dendritic A-type potassium channels.
Reference:
1 . Bock T, Negrean A, Siegelbaum AS (2022) Somatic depolarization enhances hippocampal CA1 dendritic spike propagation and distal input-driven synaptic plasticity Journal of Neuroscience [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type: Neuron or other electrically excitable cell;
Brain Region(s)/Organism: Mouse;
Cell Type(s): Hippocampus CA1 pyramidal GLU cell;
Channel(s): I R; I T low threshold; I A; I h; I K; I K,Ca;
Gap Junctions:
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Simulation Environment: NEURON; Python;
Model Concept(s): Calcium dynamics; Synaptic Plasticity;
Implementer(s): Negrean, Adrian [negreanadrian at gmail.com]; Bock, Tobias [htb2110 at columbia.edu];
Search NeuronDB for information about:  Hippocampus CA1 pyramidal GLU cell; I T low threshold; I A; I K; I h; I K,Ca; I R;
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