Integrated Oscillator Model for pancreatic islet beta-cells (Marinelli et al., 2022)

 Download zip file 
Help downloading and running models
Accession:267564
This version of the Integrated Oscillator Model for pancreatic beta-cells includes variables for oxidative phosphorylation, as well as glycolysis, electrical activity, and calcium dynamics.
Reference:
1 . Marinelli I, Thompson BM, Parekh VS, Fletcher PA, Gerardo-Giorda L, Sherman AS, Satin LS, Bertram R (2022) Oscillations in K(ATP) Conductance Drive Slow Calcium Oscillations in Pancreatic Beta-Cells Biophys J 121(8):1449-1464 [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type: Neuron or other electrically excitable cell;
Brain Region(s)/Organism:
Cell Type(s): Pancreatic Beta Cell;
Channel(s): ATP-senstive potassium current;
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment: XPPAUT;
Model Concept(s): Bursting;
Implementer(s): Bertram, Richard [rbertram at fsu.edu];
Search NeuronDB for information about:  ATP-senstive potassium current;
 
/
IOM
                            
File not selected

<- Select file from this column.
Loading data, please wait...