Model for pancreatic beta-cells with two isoforms of PFK (Marinelli et al., 2022)

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Accession:267565
This version of the Integrated Oscillator Model has two PFK isoforms, as well as modules for oxidative phosphorylation, electrical activity, and intracellular calcium.
Reference:
1 . Marinelli I, Parekh V, Fletcher P, Thompson B, Ren J, Tang X, Saunders TL, Ha J, Sherman A, Bertram R, Satin LS (2022) Slow Oscillations Persist in Pancreatic Beta Cells Lacking Phosphofructokinase M Biophys J 121(5):692-704 [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type: Neuron or other electrically excitable cell;
Brain Region(s)/Organism:
Cell Type(s):
Channel(s): ATP-senstive potassium current;
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment: XPP;
Model Concept(s): Bursting;
Implementer(s): Bertram, Richard [rbertram at fsu.edu];
Search NeuronDB for information about:  ATP-senstive potassium current;
 
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BJ_22a
                            
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