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CA1 pyramidal neuron: effects of Ih on distal inputs (Migliore et al 2004)
 
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Accession:
32992
NEURON mod files from the paper: M. Migliore, L. Messineo, M. Ferrante Dendritic Ih selectively blocks temporal summation of unsynchronized distal inputs in CA1 pyramidal neurons, J.Comput. Neurosci. 16:5-13 (2004). The model demonstrates how the dendritic Ih in pyramidal neurons could selectively suppress AP generation for a volley of excitatory afferents when they are asynchronously and distally activated.
Reference:
1 .
Migliore M, Messineo L, Ferrante M (2004) Dendritic Ih selectively blocks temporal summation of unsynchronized distal inputs in CA1 pyramidal neurons.
J Comput Neurosci
16
:5-13
[
PubMed
]
Model Information
(Click on a link to find other models with that property)
Model Type:
Dendrite;
Brain Region(s)/Organism:
Cell Type(s):
Hippocampus CA1 pyramidal GLU cell;
Channel(s):
I Na,t;
I A;
I K;
I h;
Gap Junctions:
Receptor(s):
AMPA;
Gene(s):
Transmitter(s):
Simulation Environment:
NEURON;
Model Concept(s):
Action Potential Initiation;
Dendritic Action Potentials;
Synchronization;
Active Dendrites;
Detailed Neuronal Models;
Action Potentials;
Implementer(s):
Migliore, Michele [Michele.Migliore at Yale.edu];
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for information about:
Hippocampus CA1 pyramidal GLU cell
;
AMPA
;
I Na,t
;
I A
;
I K
;
I h
;
/
synchro-ca1
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