I A in Kenyon cells resemble Shaker currents (Pelz et al 1999)

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Accession:34560
Cultured Kenyon cells from the mushroom body of the honeybee, Apis mellifera, show a voltage-gated, fast transient K1 current that is sensitive to 4-aminopyridine, an A current. The kinetic properties of this A current and its modulation by extracellular K1 ions were investigated in vitro with the whole cell patch-clamp technique. The A current was isolated from other voltage-gated currents either pharmacologically or with suitable voltage-clamp protocols. Hodgkin- and Huxley-style mathematical equations were used for the description of this current and for the simulation of action potentials in a Kenyon cell model. The data of the A current were incorporated into a reduced computational model of the voltage-gated currents of Kenyon cells. In addition, the model contained a delayed rectifier K current, a Na current, and a leakage current. The model reproduces several experimental features and makes predictions. See paper for details and results.
Reference:
1 . Pelz C, Jander J, Rosenboom H, Hammer M, Menzel R (1999) IA in Kenyon cells of the mushroom body of honeybees resembles shaker currents: kinetics, modulation by K+, and simulation. J Neurophysiol 81:1749-59 [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type: Neuron or other electrically excitable cell;
Brain Region(s)/Organism:
Cell Type(s): Honeybee kenyon cell;
Channel(s): I Na,t; I A; I K;
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment: SNNAP;
Model Concept(s): Ion Channel Kinetics; Parameter Fitting; Action Potentials; Invertebrate;
Implementer(s): Baxter, Douglas;
Search NeuronDB for information about:  I Na,t; I A; I K; 
README_Pelz.txt

This simulation is under construction.  It will reproduce 
the model of a Kenyon cell originally developed and 
published by:

Pelz, C., Jander, J., Rosenboom, H., Hammer, M. and Menzel, R. 
(1999)  IA in Kenyon cells of the mushroom body of honeybees
resembles shaker currents: kinetics, modulation by K+, and
simulation.  J. Neurophysiol.  81: 1749-1759.

Example use:

Start SNNAP (double click on the SNNAP.jar file)
click on "Run Simulation"
Then in the new window "File"->"Load Simulation"
browse to and load Kenyon_Ka_VC.smu file to load a simulation
then and click "Run Batch" and open Ka_VC.bch to generate
a figure similar to Fig 12 in the above publication
(see Fig12Model.jpg for what it should look like when done).
See http://snnap.uth.tmc.edu/ to download SNNAP

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