Regulation of a slow STG rhythm (Nadim et al 1998)

 Download zip file   Auto-launch 
Help downloading and running models
Accession:3511
Frequency regulation of a slow rhythm by a fast periodic input. Nadim, F., Manor, Y., Nusbaum, M. P., Marder, E. (1998) J. Neurosci. 18: 5053-5067
Reference:
1 . Nadim F, Manor Y, Nusbaum MP, Marder E (1998) Frequency regulation of a slow rhythm by a fast periodic input. J Neurosci 18:5053-67 [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type: Realistic Network;
Brain Region(s)/Organism: Stomatogastric ganglion;
Cell Type(s): Stomatogastric Ganglion (STG) Modulatory commissural neuron 1 (MCN1); Stomatogastric Ganglion (STG) interneuron 1 (Int1); Stomatogastric Ganglion (STG) Lateral Gastric (LG) cell;
Channel(s): I Na,t; I K;
Gap Junctions: Gap junctions;
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment: NEURON;
Model Concept(s): Temporal Pattern Generation; Invertebrate;
Implementer(s): Nadim, Farzan [Farzan at andromeda.Rutgers.edu];
Search NeuronDB for information about:  I Na,t; I K;
INDEPENDENT {t FROM 0 TO 1 WITH 1 (ms)}
NEURON {
	POINT_PROCESS gapvdep
	NONSPECIFIC_CURRENT i
	RANGE gg,i,slow
	POINTER vpregap
}
PARAMETER {
	v (millivolt)
	vpregap (millivolt)
	gg = 5e-4 (micromho)
}

STATE { slow
}
ASSIGNED {
	i (nanoamp)
}
BREAKPOINT {
	SOLVE sssss METHOD cnexp
	i = (v - vpregap)*gg*(vdepfac(v-slow))
VERBATIM

ENDVERBATIM
}

DERIVATIVE sssss {
	slow' = (vpregap-slow)/tau_slow(vpregap)
}




FUNCTION vdepfac(v){
vdepfac = 1.0/(1+exp(-(0.12*(v-5))))

}

FUNCTION tau_slow(ww){
tau_slow=0.2+200/(1+exp(-0.5*(ww+50)))
}








Loading data, please wait...