Regulation of a slow STG rhythm (Nadim et al 1998)

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Accession:3511
Frequency regulation of a slow rhythm by a fast periodic input. Nadim, F., Manor, Y., Nusbaum, M. P., Marder, E. (1998) J. Neurosci. 18: 5053-5067
Reference:
1 . Nadim F, Manor Y, Nusbaum MP, Marder E (1998) Frequency regulation of a slow rhythm by a fast periodic input. J Neurosci 18:5053-67 [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type: Realistic Network;
Brain Region(s)/Organism: Stomatogastric ganglion;
Cell Type(s): Stomatogastric Ganglion (STG) Modulatory commissural neuron 1 (MCN1); Stomatogastric Ganglion (STG) interneuron 1 (Int1); Stomatogastric Ganglion (STG) Lateral Gastric (LG) cell;
Channel(s): I Na,t; I K;
Gap Junctions: Gap junctions;
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment: NEURON;
Model Concept(s): Temporal Pattern Generation; Invertebrate;
Implementer(s): Nadim, Farzan [Farzan at andromeda.Rutgers.edu];
Search NeuronDB for information about:  I Na,t; I K;
INDEPENDENT {t FROM 0 TO 1 WITH 1 (ms)}

NEURON {
	POINT_PROCESS mcn1_int1syn
	POINTER vpre
	RANGE gmax, g, e, i
	NONSPECIFIC_CURRENT i
}
UNITS {
	(nA) = (nanoamp)
	(mV) = (millivolt)
	(umho) = (micromho)
}

PARAMETER {
	gmax=0 	(umho)
	e=0	(mV)
	v	(mV)
}

STATE { synon synoff
}

ASSIGNED {
	i (nA)
	g (umho)
	vpre (mV)
}



BREAKPOINT {

	SOLVE syn METHOD sparse
	g = gmax *synon
	i = g*(v - e)

}

KINETIC syn {

	~ synoff <-> synon (syninf(vpre)/tausyn(vpre),(1-syninf(vpre))/tausyn(vpre))

}

INITIAL {
	synon = 0.0
	synoff = 1.0
}

FUNCTION syninf(v){
	syninf = 1/(1+exp(-(v+50)))
}

: IMPORTANT! PLEASE LET THE FOLLOWING FUNCTION BE ON _ONE_ LINE!
FUNCTION tausyn(v){ tausyn = 30}

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