Find models by
Find models for
Find models of
Electrical synapses (gap junctions)
SenseLab mailing list
ModelDB related resources
Computational neuroscience ecosystem
Models in a git repository
CN bushy, stellate neurons (Rothman, Manis 2003)
Download zip file
Help downloading and running models
Using kinetic data from three different K+ currents in acutely isolated neurons, a single electrical compartment model representing the soma of a ventral cochlear nucleus (VCN) neuron was created. The K+ currents include a fast transient current (IA), a slow-inactivating low-threshold current (ILT), and a noninactivating high-threshold current (IHT). The model also includes a fast-inactivating Na+ current, a hyperpolarization-activated cation current (Ih), and 1-50 auditory nerve synapses. With this model, the role IA, ILT, and IHT play in shaping the discharge patterns of VCN cells is explored. Simulation results indicate these currents have specific roles in shaping the firing patterns of stellate and bushy CN cells. (see readme.txt and the papers, esp 2003c, for details). Any questions regarding these implementations should be directed to: firstname.lastname@example.org 2 April 2004 Paul B Manis, Ph.D.
Rothman JS, Manis PB (2003) The roles potassium currents play in regulating the electrical activity of ventral cochlear nucleus neurons.
Rothman JS, Manis PB (2003) Kinetic analyses of three distinct potassium conductances in ventral cochlear nucleus neurons.
Rothman JS, Manis PB (2003) Differential expression of three distinct potassium currents in the ventral cochlear nucleus.
(Click on a link to find other models with that property)
Neuron or other electrically excitable cell;
Cochlear nucleus bushy GLU cell;
CN stellate cell;
I L high threshold;
Temporal Pattern Generation;
Manis, Paul B [PManis at med.unc.edu];
for information about:
Cochlear nucleus bushy GLU cell
I L high threshold
Other models using hcno.mod:
CN Octopus Cell: Ih current (Bal, Oertel 2000)
Other models using leak.mod:
Oscillating neurons in the cochlear nucleus (Bahmer Langner 2006a, b, and 2007)
File not selected
<- Select file from this column.
Load Model Views
Type IIo (Octopus)
Loading data, please wait...