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Cardiac Atrial Cell (Courtemanche et al 1998)
 
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Accession:
3800
Marc Courtemanche, Rafael J. Ramirez, and Stanley Nattel. Ionic mechanisms underlying human atrial action potential properties insights from a mathematical model Am J Physiol Heart Circ Physiol 1998 275: H301-H321. The implementation of this model in NEURON was contributed by Ingemar Jacobson.
Reference:
1 .
Courtemanche M, Ramirez RJ, Nattel S (1998) Ionic mechanisms underlying human atrial action potential properties: insights from a mathematical model.
Am J Physiol
275
:H301-21
[
PubMed
]
Model Information
(Click on a link to find other models with that property)
Model Type:
Neuron or other electrically excitable cell;
Brain Region(s)/Organism:
Cell Type(s):
Cardiac atrial cell;
Heart cell;
Channel(s):
I Na,t;
I L high threshold;
I K;
I Sodium;
I Calcium;
I Potassium;
Na/Ca exchanger;
Gap Junctions:
Receptor(s):
Gene(s):
Kv4.3 KCND3;
Kv1.5 KCNA5;
HERG KCNH2;
Transmitter(s):
Simulation Environment:
NEURON;
Model Concept(s):
Ion Channel Kinetics;
Action Potentials;
Heart disease;
Calcium dynamics;
Implementer(s):
Jacobson, Ingemar [Ingemar.Jacobson at astrazeneca.com];
Search NeuronDB
for information about:
I Na,t
;
I L high threshold
;
I K
;
I Sodium
;
I Calcium
;
I Potassium
;
Na/Ca exchanger
;
Download the displayed file
/
cardiac1998
Readme
cadynam.mod
cajsr.mod
cajsracc.mod
cansracc.mod
capump.mod
ical.mod
ik1.mod
ikr.mod
iks.mod
ikur.mod
inaf.mod
ionback.mod
ito.mod
kcum.mod
nacaex.mod
nacum.mod
nipace.mod
nkpump.mod
aboutatrial.hoc
ap.gif
atrialnew.ses
mosinit.hoc
startatrial1.hoc
startatrial2.hoc
load_file("startatrial2.hoc") atol_ = 1e-3 cvode.atol(atol_) cvode_active(1) run()
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