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Pyramidal Neuron: Deep, Thalamic Relay and Reticular, Interneuron (Destexhe et al 1998, 2001)
 
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Accession:
3817
This package shows single-compartment models of different classes of cortical neurons, such as the "regular-spiking", "fast-spiking" and "bursting" (LTS) neurons. The mechanisms included are the Na+ and K+ currents for generating action potentials (INa, IKd), the T-type calcium current (ICaT), and a slow voltage-dependent K+ current (IM). See http://cns.fmed.ulaval.ca/alain_demos.html
References:
1 .
Destexhe A, Contreras D, Steriade M (1998) Mechanisms underlying the synchronizing action of corticothalamic feedback through inhibition of thalamic relay cells.
J Neurophysiol
79
:999-1016
[
PubMed
]
2 .
Destexhe A, Contreras D, Steriade M (2001) LTS cells in cerebral cortex and their role in generating spike-and-wave oscillations.
Neurocomputing
38
:555-563
3 .
Destexhe A, Sejnowski TJ (2001)
Thalamocortical Assemblies-How Ion Channels, Single Neurons and large-Scale Networks Organize Sleep
Model Information
(Click on a link to find other models with that property)
Model Type:
Neuron or other electrically excitable cell;
Brain Region(s)/Organism:
Cell Type(s):
Thalamus geniculate nucleus/lateral principal GLU cell;
Thalamus reticular nucleus GABA cell;
Neocortex L5/6 pyramidal GLU cell;
Neocortex spiking regular (RS) neuron;
Neocortex spiking low threshold (LTS) neuron;
Channel(s):
I Na,t;
I T low threshold;
I K;
I M;
I Sodium;
I Calcium;
I Potassium;
Gap Junctions:
Receptor(s):
GabaA;
GabaB;
AMPA;
Gaba;
Gene(s):
Transmitter(s):
Simulation Environment:
NEURON;
Model Concept(s):
Activity Patterns;
Bursting;
Action Potentials;
Calcium dynamics;
Implementer(s):
Destexhe, Alain [Destexhe at iaf.cnrs-gif.fr];
Search NeuronDB
for information about:
Thalamus geniculate nucleus/lateral principal GLU cell
;
Thalamus reticular nucleus GABA cell
;
Neocortex L5/6 pyramidal GLU cell
;
GabaA
;
GabaB
;
AMPA
;
Gaba
;
I Na,t
;
I T low threshold
;
I K
;
I M
;
I Sodium
;
I Calcium
;
I Potassium
;
/
cortex
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