The present modeling study suggests that persistent, low-threshold, rapidly activating
sodium currents have a key role in breakdown of accommodation, and that breakdown of
accommodation can be used as a tool for studying persistent sodium current under normal and
pathological conditions. See paper for more and details.
Hennings K, Arendt-Nielsen L, Andersen OK (2005) Breakdown of accommodation in nerve: a possible role for persistent sodium current. Theor Biol Med Model 2:16 [PubMed]