Coding of stimulus frequency by latency in thalamic networks (Golomb et al 2005)

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Accession:58582
The paper presents models of the rat vibrissa processing system including the posterior medial (POm) thalamus, ventroposterior medial (VPm) thalamus, and GABAB- mediated feedback inhibition from the reticular thalamic (Rt) nucleus. A clear match between the experimentally measured spike-rates and the numerically calculated rates for the full model occurs when VPm thalamus receives stronger brainstem input and weaker GABAB-mediated inhibition than POm thalamus.
Reference:
1 . Golomb D, Ahissar E, Kleinfeld D (2006) Coding of stimulus frequency by latency in thalamic networks through the interplay of GABAB-mediated feedback and stimulus shape. J Neurophysiol 95:1735-50 [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type: Realistic Network;
Brain Region(s)/Organism: Thalamus;
Cell Type(s): Thalamus geniculate nucleus/lateral principal GLU cell; Thalamus reticular nucleus GABA cell;
Channel(s):
Gap Junctions:
Receptor(s): GabaA; GabaB; AMPA;
Gene(s):
Transmitter(s): Gaba; Glutamate;
Simulation Environment: C or C++ program;
Model Concept(s): Simplified Models; Rate-coding model neurons;
Implementer(s): Golomb, David [golomb at bgu.ac.il];
Search NeuronDB for information about:  Thalamus geniculate nucleus/lateral principal GLU cell; Thalamus reticular nucleus GABA cell; GabaA; GabaB; AMPA; Gaba; Glutamate; 
# CDEBUGFLAGS = -g
CDEBUGFLAGS = -O2
CC   = cc

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plp:    plp.c plp.h nr.c nr.h
	${CC} ${CFLAGS} plp.c nr.c  -lm -o plp.ex

tlp:    tlp.c tplp.c tlp.h tplp.h nr.c nr.h
	${CC} ${CFLAGS} tlp.c tplp.c nr.c -lm -o tlp.ex

stm:    stm.c stm.h nr.c nr.h
	${CC} ${CFLAGS} stm.c nr.c -lm -o stm.ex

intnor: intnor.c intnor.h nr.c nr.h
	${CC} ${CFLAGS} intnor.c  nr.c -lm -o intnor.ex

clean:
	/bin/rm -f *.o

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