Advanced search
SenseLab
SimToolDB
ModelDB Help
User account
Login
Register
Find models by
Model name
First author
Each author
Region(circuits)
Find models for
Cell type
Current
Receptor
Gene
Transmitters
Concept
Simulators
Methods
Find models of
Realistic Networks
Neurons
Electrical synapses (gap junctions)
Chemical synapses
Ion channels
Neuromuscular junctions
Axons
Pathophysiology
Other resources
SenseLab mailing list
ModelDB related resources
Computational neuroscience ecosystem
Models in a git repository
A single column thalamocortical network model (Traub et al 2005)
Download zip file
Help downloading and running models
Model Information
Model File
Citations
Accession:
45539
To better understand population phenomena in thalamocortical neuronal ensembles, we have constructed a preliminary network model with 3,560 multicompartment neurons (containing soma, branching dendrites, and a portion of axon). Types of neurons included superficial pyramids (with regular spiking [RS] and fast rhythmic bursting [FRB] firing behaviors); RS spiny stellates; fast spiking (FS) interneurons, with basket-type and axoaxonic types of connectivity, and located in superficial and deep cortical layers; low threshold spiking (LTS) interneurons, that contacted principal cell dendrites; deep pyramids, that could have RS or intrinsic bursting (IB) firing behaviors, and endowed either with non-tufted apical dendrites or with long tufted apical dendrites; thalamocortical relay (TCR) cells; and nucleus reticularis (nRT) cells. To the extent possible, both electrophysiology and synaptic connectivity were based on published data, although many arbitrary choices were necessary.
References:
1 .
Traub RD, Contreras D, Cunningham MO, Murray H, LeBeau FE, Roopun A, Bibbig A, Wilent WB, Higley MJ, Whittington MA (2005) Single-column thalamocortical network model exhibiting gamma oscillations, sleep spindles, and epileptogenic bursts.
J Neurophysiol
93
:2194-232
[
PubMed
]
2 .
Traub RD, Contreras D, Whittington MA (2005) Combined experimental/simulation studies of cellular and network mechanisms of epileptogenesis in vitro and in vivo.
J Clin Neurophysiol
22
:330-42
[
PubMed
]
Model Information
(Click on a link to find other models with that property)
Model Type:
Realistic Network;
Brain Region(s)/Organism:
Neocortex;
Thalamus;
Cell Type(s):
Thalamus geniculate nucleus/lateral principal GLU cell;
Thalamus reticular nucleus GABA cell;
Neocortex U1 L6 pyramidal corticalthalamic GLU cell;
Neocortex U1 L2/6 pyramidal intratelencephalic GLU cell;
Neocortex fast spiking (FS) interneuron;
Neocortex spiking regular (RS) neuron;
Neocortex spiking low threshold (LTS) neuron;
Channel(s):
I Na,p;
I Na,t;
I L high threshold;
I T low threshold;
I A;
I K;
I M;
I h;
I K,Ca;
I Calcium;
I A, slow;
Gap Junctions:
Gap junctions;
Receptor(s):
GabaA;
AMPA;
NMDA;
Gene(s):
Transmitter(s):
Simulation Environment:
NEURON;
FORTRAN;
Model Concept(s):
Activity Patterns;
Bursting;
Temporal Pattern Generation;
Oscillations;
Simplified Models;
Epilepsy;
Sleep;
Spindles;
Implementer(s):
Traub, Roger D [rtraub at us.ibm.com];
Search NeuronDB
for information about:
Thalamus geniculate nucleus/lateral principal GLU cell
;
Thalamus reticular nucleus GABA cell
;
Neocortex U1 L2/6 pyramidal intratelencephalic GLU cell
;
Neocortex U1 L6 pyramidal corticalthalamic GLU cell
;
GabaA
;
AMPA
;
NMDA
;
I Na,p
;
I Na,t
;
I L high threshold
;
I T low threshold
;
I A
;
I K
;
I M
;
I h
;
I K,Ca
;
I Calcium
;
I A, slow
;
Files displayed below are from the
ifc fortran
g77
NEURON
neuroConstruct
implementation
/
nrntraub
dat
deepaxax_v_F.dat
*
Other models using deepaxax_v_F.dat:
A single column thalamocortical network model (Traub et al 2005)
A single column thalamocortical network model (Traub et al 2005)
A single column thalamocortical network model (Traub et al 2005)
Deconstruction of cortical evoked potentials generated by subthalamic DBS (Kumaravelu et al 2018)
Deconstruction of cortical evoked potentials generated by subthalamic DBS (Kumaravelu et al 2018)
Deconstruction of cortical evoked potentials generated by subthalamic DBS (Kumaravelu et al 2018)
Deconstruction of cortical evoked potentials generated by subthalamic DBS (Kumaravelu et al 2018)
deepbask_v_F.dat
*
Other models using deepbask_v_F.dat:
A single column thalamocortical network model (Traub et al 2005)
A single column thalamocortical network model (Traub et al 2005)
A single column thalamocortical network model (Traub et al 2005)
Deconstruction of cortical evoked potentials generated by subthalamic DBS (Kumaravelu et al 2018)
Deconstruction of cortical evoked potentials generated by subthalamic DBS (Kumaravelu et al 2018)
Deconstruction of cortical evoked potentials generated by subthalamic DBS (Kumaravelu et al 2018)
Deconstruction of cortical evoked potentials generated by subthalamic DBS (Kumaravelu et al 2018)
deepLTS_v_F.dat
*
Other models using deepLTS_v_F.dat:
A single column thalamocortical network model (Traub et al 2005)
Deconstruction of cortical evoked potentials generated by subthalamic DBS (Kumaravelu et al 2018)
Deconstruction of cortical evoked potentials generated by subthalamic DBS (Kumaravelu et al 2018)
nointeraction.spk
*
Other models using nointeraction.spk:
Deconstruction of cortical evoked potentials generated by subthalamic DBS (Kumaravelu et al 2018)
nontuftRS_v_F.dat
*
Other models using nontuftRS_v_F.dat:
Deconstruction of cortical evoked potentials generated by subthalamic DBS (Kumaravelu et al 2018)
nrntest.spk
*
Other models using nrntest.spk:
Deconstruction of cortical evoked potentials generated by subthalamic DBS (Kumaravelu et al 2018)
nRT_v_F.dat
*
Other models using nRT_v_F.dat:
Deconstruction of cortical evoked potentials generated by subthalamic DBS (Kumaravelu et al 2018)
p2ctest.spk
*
Other models using p2ctest.spk:
Deconstruction of cortical evoked potentials generated by subthalamic DBS (Kumaravelu et al 2018)
spinstell_v_F.dat
*
Other models using spinstell_v_F.dat:
Deconstruction of cortical evoked potentials generated by subthalamic DBS (Kumaravelu et al 2018)
supaxax_v_F.dat
*
Other models using supaxax_v_F.dat:
A single column thalamocortical network model (Traub et al 2005)
A single column thalamocortical network model (Traub et al 2005)
A single column thalamocortical network model (Traub et al 2005)
Deconstruction of cortical evoked potentials generated by subthalamic DBS (Kumaravelu et al 2018)
Deconstruction of cortical evoked potentials generated by subthalamic DBS (Kumaravelu et al 2018)
Deconstruction of cortical evoked potentials generated by subthalamic DBS (Kumaravelu et al 2018)
Deconstruction of cortical evoked potentials generated by subthalamic DBS (Kumaravelu et al 2018)
supbask_v_F.dat
*
Other models using supbask_v_F.dat:
A single column thalamocortical network model (Traub et al 2005)
A single column thalamocortical network model (Traub et al 2005)
A single column thalamocortical network model (Traub et al 2005)
Deconstruction of cortical evoked potentials generated by subthalamic DBS (Kumaravelu et al 2018)
Deconstruction of cortical evoked potentials generated by subthalamic DBS (Kumaravelu et al 2018)
Deconstruction of cortical evoked potentials generated by subthalamic DBS (Kumaravelu et al 2018)
Deconstruction of cortical evoked potentials generated by subthalamic DBS (Kumaravelu et al 2018)
supLTS_v_F.dat
*
Other models using supLTS_v_F.dat:
A single column thalamocortical network model (Traub et al 2005)
Deconstruction of cortical evoked potentials generated by subthalamic DBS (Kumaravelu et al 2018)
Deconstruction of cortical evoked potentials generated by subthalamic DBS (Kumaravelu et al 2018)
suppyrFRB_v_F.dat
*
Other models using suppyrFRB_v_F.dat:
Deconstruction of cortical evoked potentials generated by subthalamic DBS (Kumaravelu et al 2018)
suppyrRS_v_F.dat
*
Other models using suppyrRS_v_F.dat:
Deconstruction of cortical evoked potentials generated by subthalamic DBS (Kumaravelu et al 2018)
TCR_v_F.dat
*
Other models using TCR_v_F.dat:
Deconstruction of cortical evoked potentials generated by subthalamic DBS (Kumaravelu et al 2018)
tuftIB_v_F.dat
*
Other models using tuftIB_v_F.dat:
Deconstruction of cortical evoked potentials generated by subthalamic DBS (Kumaravelu et al 2018)
tuftRS_v_F.dat
*
Other models using tuftRS_v_F.dat:
Deconstruction of cortical evoked potentials generated by subthalamic DBS (Kumaravelu et al 2018)
File not selected
<- Select file from this column.
Loading data, please wait...
