Find models by
Find models for
Find models of
Electrical synapses (gap junctions)
SenseLab mailing list
ModelDB related resources
Computational neuroscience ecosystem
Models in a git repository
Differential modulation of pattern and rate in a dopamine neuron model (Canavier and Landry 2006)
Download zip file
Help downloading and running models
Versions on GitHub
"A stylized, symmetric, compartmental model of a dopamine neuron in vivo shows how rate and pattern can be modulated either concurrently or differentially. If two or more parameters in the model are varied concurrently, the baseline firing rate and the extent of bursting become decorrelated, which provides an explanation for the lack of a tight correlation in vivo and is consistent with some independence of the mechanisms that generate baseline firing rates versus bursting. ..." See paper for more and details.
Canavier CC, Landry RS (2006) An increase in AMPA and a decrease in SK conductance increase burst firing by different mechanisms in a model of a dopamine neuron in vivo.
(Click on a link to find other models with that property)
Neuron or other electrically excitable cell;
Substantia nigra pars compacta DA cell;
I L high threshold;
I T low threshold;
Detailed Neuronal Models;
Kuznetsova, Anna [anna.kuznetsova at utsa.edu];
for information about:
Substantia nigra pars compacta DA cell
I L high threshold
I T low threshold
File not selected
<- Select file from this column.
Loading data, please wait...