SenseLab Home ModelDB Home

Citations for T channel currents (Vitko et al 2005)



Vitko I, Chen Y,Arias JM, Shen Y, Wu XR, Perez-Reyes E (2005) Functional Characterization and Neuronal Modeling of the Effects of Childhood Absence Epilepsy Variants of CACNA1H, a T-Type Calcium Channel J Neurosci 25:4844-4855 [PubMed]

References and models cited by this paper

References and models that cite this paper

Aizawa M, Ito Y, Fukuda H (1997) Pharmacological profiles of generalized absence seizures in lethargic, stargazer and gamma-hydroxybutyrate-treated model mice. Neurosci Res 29:17-25

Berjukow S, Doring F, Froschmayr M, Grabner M, Glossmann H, Hering S (1996) Endogenous calcium channels in human embryonic kidney (HEK293) cells. Br J Pharmacol 118:748-54

Bijlenga P, Liu JH, Espinos E, Haenggeli CA, Fischer-Lougheed J, Bader CR, Bernheim L (2000) T-type alpha 1H Ca2+ channels are involved in Ca2+ signaling during terminal differentiation (fusion) of human myoblasts. Proc Natl Acad Sci U S A 97:7627-32 [PubMed]

Bossu JL, Feltz A (1986) Inactivation of the low-threshold transient calcium current in rat sensory neurones: evidence for a dual process. J Physiol 376:341-57 [PubMed]

Burgess DE, Crawford O, Delisle BP, Satin J (2002) Mechanism of inactivation gating of human T-type (low-voltage activated) calcium channels. Biophys J 82:1894-906

Chemin J, Monteil A, Briquaire C, Richard S, Perez-Reyes E, Nargeot J, Lory P (2000) Overexpression of T-type calcium channels in HEK-293 cells increases intracellular calcium without affecting cellular proliferation. FEBS Lett 478:166-72 [PubMed]

Chemin J, Monteil A, Perez-Reyes E, Bourinet E, Nargeot J, Lory P (2002) Specific contribution of human T-type calcium channel isotypes (alpha(1G), alpha(1H) and alpha(1I)) to neuronal excitability. J Physiol 540:3-14 [PubMed]

Chen XL, Bayliss DA, Fern RJ, Barrett PQ (1999) A role for T-type Ca2+ channels in the synergistic control of aldosterone production by ANG II and K+. Am J Physiol 276:F674-83

Chen Y, Lu J, Pan H, Zhang Y, Wu H, Xu K, Liu X, Jiang Y, Bao X, Yao Z, Ding K, Lo WH, Qiang (2003) Association between genetic variation of CACNA1H and childhood absence epilepsy. Ann Neurol 54:239-43

Chen Y, Lu J, Zhang Y, Pan H, Wu H, Xu K, Liu X, Jiang Y, Bao X, Zhou J, Liu W, Shi G, Shen Y (2003) T-type calcium channel gene alpha (1G) is not associated with childhood absence epilepsy in the Chinese Han population. Neurosci Lett 341:29-32

Coulter DA, Huguenard JR, Prince DA (1989) Characterization of ethosuximide reduction of low-threshold calcium current in thalamic neurons. Ann Neurol 25:582-93 [PubMed]

Cribbs LL, Lee JH, Yang J, Satin J, Zhang Y, Daud A, Barclay J, Williamson MP, Fox M, Rees M, (1998) Cloning and characterization of alpha1H from human heart, a member of the T-type Ca2+ channel gene family. Circ Res 83:103-9 [PubMed]

Crunelli V, Leresche N (2002) Childhood absence epilepsy: genes, channels, neurons and networks. Nat Rev Neurosci 3:371-82 [PubMed]

Crunelli V, Toth TI, Cope DW, Blethyn K, Hughes SW (2005) The 'window' T-type calcium current in brain dynamics of different behavioural states. J Physiol 562:121-9 [PubMed]

Destexhe A, Bal T, McCormick DA, Sejnowski TJ (1996) Ionic mechanisms underlying synchronized oscillations and propagating waves in a model of ferret thalamic slices. J Neurophysiol 76:2049-70 [Journal] [PubMed]
   Thalamocortical and Thalamic Reticular Network (Destexhe et al 1996) [Model]

Destexhe A, Contreras D, Steriade M (2001) LTS cells in cerebral cortex and their role in generating spike-and-wave oscillations. Neurocomputing 38:555-563 [Journal]
   Pyramidal Neuron: Deep, Thalamic Relay and Reticular, Interneuron (Destexhe et al 1998, 2001) [Model]

Destexhe A, Contreras D, Steriade M, Sejnowski TJ, Huguenard JR (1996) In vivo, in vitro, and computational analysis of dendritic calcium currents in thalamic reticular neurons. J Neurosci 16:169-85 [Journal] [PubMed]
   Thalamic reticular neurons: the role of Ca currents (Destexhe et al 1996) [Model]

Destexhe A, Neubig M, Ulrich D, Huguenard J (1998) Dendritic low-threshold calcium currents in thalamic relay cells. J Neurosci 18:3574-88 [Journal] [PubMed]
   Low Threshold Calcium Currents in TC cells (Destexhe et al 1998) [Model]

Destexhe A, Sejnowski TJ (2003) Interactions between membrane conductances underlying thalamocortical slow-wave oscillations. Physiol Rev 83:1401-53 [PubMed]

Dubel SJ, Altier C, Chaumont S, Lory P, Bourinet E, Nargeot J (2004) Plasma membrane expression of T-type calcium channel alpha(1) subunits is modulated by high voltage-activated auxiliary subunits. J Biol Chem 279:29263-9

Frazier CJ, Serrano JR, George EG, Yu X, Viswanathan A, Perez-Reyes E, Jones SW (2001) Gating kinetics of the alpha1I T-type calcium channel. J Gen Physiol 118:457-70 [PubMed]

Gargus JJ (2003) Unraveling monogenic channelopathies and their implications for complex polygenic disease. Am J Hum Genet 72:785-803 [PubMed]

Gloor P, Fariello RG (1988) Generalized epilepsy: some of its cellular mechanisms differ from those of focal epilepsy. Trends Neurosci 11:63-8 [PubMed]

Gomora JC, Daud AN, Weiergraber M, Perez-Reyes E (2001) Block of cloned human T-type calcium channels by succinimide antiepileptic drugs. Mol Pharmacol 60:1121-32

Gomora JC, Murbartian J, Arias JM, Lee JH, Perez-Reyes E (2002) Cloning and expression of the human T-type channel Ca(v)3.3: insights into prepulse facilitation. Biophys J 83:229-41

Heron SE, Phillips HA, Mulley JC, Mazarib A, Neufeld MY, Berkovic SF, Scheffer IE (2004) Genetic variation of CACNA1H in idiopathic generalized epilepsy. Ann Neurol 55:595-6

Herrington J, Lingle CJ (1992) Kinetic and pharmacological properties of low voltage-activated Ca2+ current in rat clonal (GH3) pituitary cells. J Neurophysiol 68:213-32 [Journal]

Hines ML, Carnevale NT (2001) NEURON: a tool for neuroscientists. Neuroscientist 7:123-35 [Journal] [PubMed]
   Spatial gridding and temporal accuracy in NEURON (Hines and Carnevale 2001) [Model]

Hirakawa M, Tanaka T, Hashimoto Y, Kuroda M, Takagi T, Nakamura Y (2002) JSNP: a database of common gene variations in the Japanese population. Nucleic Acids Res 30:158-62

Huguenard JR (1999) Neuronal circuitry of thalamocortical epilepsy and mechanisms of antiabsence drug action. Adv Neurol 79:991-9 [PubMed]

Huguenard JR, Prince DA (1992) A novel T-type current underlies prolonged Ca(2+)-dependent burst firing in GABAergic neurons of rat thalamic reticular nucleus. J Neurosci 12:3804-17 [PubMed]

Jagannathan S, Punt EL, Gu Y, Arnoult C, Sakkas D, Barratt CL, Publicover SJ (2002) Identification and localization of T-type voltage-operated calcium channel subunits in human male germ cells. Expression of multiple isoforms. J Biol Chem 277:8449-56

Khosravani H, Altier C, Simms B, Hamming KS, Snutch TP, Mezeyova J, McRory JE, Zamponi GW (2004) Gating effects of mutations in the Cav3.2 T-type calcium channel associated with childhood absence epilepsy. J Biol Chem 279:9681-4

Kim D, Song I, Keum S, Lee T, Jeong MJ, Kim SS, McEnery MW, Shin HS (2001) Lack of the burst firing of thalamocortical relay neurons and resistance to absence seizures in mice lacking alpha(1G) T-type Ca(2+) channels. Neuron 31:35-45 [PubMed]

Klockner U, Lee JH, Cribbs LL, Daud A, Hescheler J, Pereverzev A, Perez-Reyes E, Schneider T (1999) Comparison of the Ca2 + currents induced by expression of three cloned alpha1 subunits, alpha1G, alpha1H and alpha1I, of low-voltage-activated T-type Ca2 + channels. Eur J Neurosci 11:4171-8 [PubMed]

Kuo CC, Yang S (2001) Recovery from inactivation of t-type ca2+ channels in rat thalamic neurons. J Neurosci 21:1884-92

Lambert RC, Maulet Y, Mouton J, Beattie R, Volsen S, De Waard M, Feltz A (1997) T-type Ca2+ current properties are not modified by Ca2+ channel beta subunit depletion in nodosus ganglion neurons. J Neurosci 17:6621-8

Lapie P, Goudet C, Nargeot J, Fontaine B, Lory P (1996) Electrophysiological properties of the hypokalaemic periodic paralysis mutation (R528H) of the skeletal muscle alpha 1s subunit as expressed in mouse L cells. FEBS Lett 382:244-8

Lee JH, Daud AN, Cribbs LL, Lacerda AE, Pereverzev A, Klockner U, Schneider T, Perez-Reyes E (1999) Cloning and expression of a novel member of the low voltage-activated T-type calcium channel family. J Neurosci 19:1912-21 [PubMed]

Leresche N, Parri HR, Erdemli G, Guyon A, Turner JP, Williams SR, Asprodini E, Crunelli V (1998) On the action of the anti-absence drug ethosuximide in the rat and cat thalamus. J Neurosci 18:4842-53 [PubMed]

Llinas R, Jahnsen H (1982) Electrophysiology of mammalian thalamic neurones in vitro. Nature 297:406-8 [PubMed]

Llinas RR, Ribary U, Jeanmonod D, Kronberg E, Mitra PP (1999) Thalamocortical dysrhythmia: A neurological and neuropsychiatric syndrome characterized by magnetoencephalography. Proc Natl Acad Sci U S A 96:15222-7 [PubMed]

Lossin C, Rhodes TH, Desai RR, Vanoye CG, Wang D, Carniciu S, Devinsky O, George AL (2003) Epilepsy-associated dysfunction in the voltage-gated neuronal sodium channel SCN1A. J Neurosci 23:11289-95 [PubMed]

Lossin C, Wang DW, Rhodes TH, Vanoye CG, George AL (2002) Molecular basis of an inherited epilepsy. Neuron 34:877-84 [PubMed]

Manning JP, Richards DA, Leresche N, Crunelli V, Bowery NG (2004) Cortical-area specific block of genetically determined absence seizures by ethosuximide. Neuroscience 123:5-9

McCormick DA, Contreras D (2001) On the cellular and network bases of epileptic seizures. Annu Rev Physiol 63:815-46 [PubMed]

McRory JE, Hamid J, Doering CJ, Garcia E, Parker R, Hamming K, Chen L, Hildebrand M, Beedle A (2004) The CACNA1F gene encodes an L-type calcium channel with unique biophysical properties and tissue distribution. J Neurosci 24:1707-18

McRory JE, Santi CM, Hamming KS, Mezeyova J, Sutton KG, Baillie DL, Stea A, Snutch TP (2001) Molecular and functional characterization of a family of rat brain T-type calcium channels. J Biol Chem 276:3999-4011 [Journal] [PubMed]
   T-type Calcium currents (McRory et al 2001) [Model]

Meeren HK, Pijn JP, Van Luijtelaar EL, Coenen AM, Lopes da Silva FH (2002) Cortical focus drives widespread corticothalamic networks during spontaneous absence seizures in rats. J Neurosci 22:1480-95 [PubMed]

Meisler MH, Kearney J, Ottman R, Escayg A (2001) Identification of epilepsy genes in human and mouse. Annu Rev Genet 35:567-88 [PubMed]

Perez-Reyes E (2003) Molecular physiology of low-voltage-activated t-type calcium channels. Physiol Rev 83:117-61 [PubMed]

Robinson R, Gardiner M (2000) Genetics of childhood epilepsy. Arch Dis Child 82:121-5

Sander T (1996) The genetics of idiopathic generalized epilepsy: implications for the understanding of its aetiology. Mol Med Today 2:173-80

Serrano JR, Perez-Reyes E, Jones SW (1999) State-dependent inactivation of the alpha1G T-type calcium channel. J Gen Physiol 114:185-201 [PubMed]

Steriade M (2001) Impact of network activities on neuronal properties in corticothalamic systems. J Neurophysiol 86:1-39 [Journal] [PubMed]

Talley EM, Cribbs LL, Lee JH, Daud A, Perez-Reyes E, Bayliss DA (1999) Differential distribution of three members of a gene family encoding low voltage-activated (T-type) calcium channels. J Neurosci 19:1895-911 [PubMed]

Talley EM, Solorzano G, Depaulis A, Perez-Reyes E, Bayliss DA (2000) Low-voltage-activated calcium channel subunit expression in a genetic model of absence epilepsy in the rat. Brain Res Mol Brain Res 75:159-65

Tsakiridou E, Bertollini L, de Curtis M, Avanzini G, Pape HC (1995) Selective increase in T-type calcium conductance of reticular thalamic neurons in a rat model of absence epilepsy. J Neurosci 15:3110-7 [PubMed]

van den Maagdenberg AM, Pietrobon D, Pizzorusso T, Kaja S, Broos LA, Cesetti T, van de Ven RC (2004) A Cacna1a knockin migraine mouse model with increased susceptibility to cortical spreading depression. Neuron 41:701-10

Wolfe JT, Wang H, Perez-Reyes E, Barrett PQ (2002) Stimulation of recombinant Ca(v)3.2, T-type, Ca(2+) channel currents by CaMKIIgamma(C). J Physiol 538:343-55

Zhang Y, Cribbs LL, Satin J (2000) Arachidonic acid modulation of alpha1H, a cloned human T-type calcium channel. Am J Physiol Heart Circ Physiol 278:H184-93

Zhang Y, Mori M, Burgess DL, Noebels JL (2002) Mutations in high-voltage-activated calcium channel genes stimulate low-voltage-activated currents in mouse thalamic relay neurons. J Neurosci 22:6362-71 [PubMed]

Brette R, Rudolph M, Carnevale T, Hines M, Beeman D, Bower JM, Diesmann M, Morrison A, et al. (2007) Simulation of networks of spiking neurons: A review of tools and strategies. J Comp Neurosci 23:349-98 [Journal] [PubMed]
   Networks of spiking neurons: a review of tools and strategies (Brette et al. 2007) [Model]

Cataldi M, Lariccia V, Marzaioli V, Cavaccini A, Curia G, Viggiano D, Canzoniero LM, di Renzo (2007) Zn(2+) slows down Ca(V)3.3 gating kinetics: implications for thalamocortical activity. J Neurophysiol 98:2274-84 [Journal] [PubMed]

Xu J, Clancy CE (2008) Ionic mechanisms of endogenous bursting in CA3 hippocampal pyramidal neurons: a model study. PLoS ONE 3:e2056 [Journal] [PubMed]
   Ionic mechanisms of bursting in CA3 pyramidal neurons (Xu and Clancy 2008) [Model]

(65 refs)


ModelDB Home  SenseLab Home   Help
Questions, comments, problems? Email the ModelDB Administrator
How to cite ModelDB
This site is Copyright 2014 Shepherd Lab, Yale University