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Colbert CM, Pan E (2002) Ion channel properties underlying axonal action potential initiation in pyramidal neurons. Nat Neurosci 5:533-8[PubMed]

References and models cited by this paper

References and models that cite this paper

Adams PR (1992) The platonic neuron gets the hots. Curr Biol 2:625-7 [PubMed]

Alessandri-Haber N, Paillart C, Arsac C, Gola M, Couraud F, Crest M (1999) Specific distribution of sodium channels in axons of rat embryo spinal motoneurones. J Physiol 518 ( Pt 1):203-14 [PubMed]

Andreasen M, Lambert JD (1995) Regenerative properties of pyramidal cell dendrites in area CA1 of the rat hippocampus. J Physiol 483 ( Pt 2):421-41 [PubMed]

Angelides KJ, Elmer LW, Loftus D, Elson E (1988) Distribution and lateral mobility of voltage-dependent sodium channels in neurons. J Cell Biol 106:1911-25 [PubMed]

Astman N, Gutnick MJ, Fleidervish IA (1998) Activation of protein kinase C increases neuronal excitability by regulating persistent Na+ current in mouse neocortical slices. J Neurophysiol 80:1547-51 [Journal] [PubMed]

Buhl EH, Han ZS, Lorinczi Z, Stezhka VV, Karnup SV, Somogyi P (1994) Physiological properties of anatomically identified axo-axonic cells in the rat hippocampus. J Neurophysiol 71:1289-307 [Journal] [PubMed]

Carras PL, Coleman PA, Miller RF (1992) Site of action potential initiation in amphibian retinal ganglion cells. J Neurophysiol 67:292-304 [Journal] [PubMed]

Catterall WA (1981) Localization of sodium channels in cultured neural cells. J Neurosci 1:777-83 [PubMed]

Chavez-Noriega LE, Halliwell JV, Bliss TV (1990) A decrease in firing threshold observed after induction of the EPSP-spike (E-S) component of long-term potentiation in rat hippocampal slices. Exp Brain Res 79:633-41 [PubMed]

Cobb SR, Buhl EH, Halasy K, Paulsen O, Somogyi P (1995) Synchronization of neuronal activity in hippocampus by individual GABAergic interneurons. Nature 378:75-8 [PubMed]

Colbert CM, Johnston D (1996) Axonal action-potential initiation and Na+ channel densities in the soma and axon initial segment of subicular pyramidal neurons. J Neurosci 16:6676-86 [PubMed]

Dodge FA, Cooley JW (1973) Action Potential of the Motorneuron. IBM J Res Dev 17:219-29 [Journal]

   Spinal Motor Neuron (Dodge, Cooley 1973) [Model]

Edwards E, Ottoson D (1958) The site of impulse initiation in a nerve cell of a crustacean stretch receptor. J Physiol 143:138-148

Farinas I, DeFelipe J (1991) Patterns of synaptic input on corticocortical and corticothalamic cells in the cat visual cortex. II. The axon initial segment. J Comp Neurol 304:70-7 [PubMed]

Gogan P, Gueritaud JP, Tyc-Dumont S (1983) Comparison of antidromic and orthodromic action potentials of identified motor axons in the cat's brain stem. J Physiol 335:205-20 [PubMed]

Golding NL, Spruston N (1998) Dendritic sodium spikes are variable triggers of axonal action potentials in hippocampal CA1 pyramidal neurons. Neuron 21:1189-200 [PubMed]

Hines M (1993) NEURON--a program for simulation of nerve equations. Neural Systems: Analysis And Modeling, Eeckman F, ed. pp.127

Hoffman DA, Magee JC, Colbert CM, Johnston D (1997) K+ channel regulation of signal propagation in dendrites of hippocampal pyramidal neurons. Nature 387:869-75 [PubMed]

Johnston D, Magee JC, Colbert CM, Cristie BR (1996) Active properties of neuronal dendrites. Annu Rev Neurosci 19:165-86 [PubMed]

Kloosterman F, Peloquin P, Leung LS (2001) Apical and basal orthodromic population spikes in hippocampal CA1 in vivo show different origins and patterns of propagation. J Neurophysiol 86:2435-44 [Journal] [PubMed]

Koch C (1999) Biophysics Of Computation: Information Processing in Single Neurons

Luscher HR, Larkum ME (1998) Modeling action potential initiation and back-propagation in dendrites of cultured rat motoneurons. J Neurophysiol 80:715-29 [Journal] [PubMed]

Magee JC (1998) Dendritic hyperpolarization-activated currents modify the integrative properties of hippocampal CA1 pyramidal neurons. J Neurosci 18:7613-24 [PubMed]

Mainen ZF, Joerges J, Huguenard JR, Sejnowski TJ (1995) A model of spike initiation in neocortical pyramidal neurons. Neuron 15:1427-39 [PubMed]

   Spike Initiation in Neocortical Pyramidal Neurons (Mainen et al 1995) [Model]

Matsumoto E, Rosenbluth J (1985) Plasma membrane structure at the axon hillock, initial segment and cell body of frog dorsal root ganglion cells. J Neurocytol 14:731-47 [PubMed]

Mel BW (1994) Information processing in dendritic trees. Neural Comput 6:1031-1085

Moore JW, Stockbridge N, Westerfield M (1983) On the site of impulse initiation in a neurone. J Physiol 336:301-11 [PubMed]

   Site of impulse initiation in a neuron (Moore et al 1983) [Model]

Moore JW, Westerfield M (1983) Action potential propagation and threshold parameters in inhomogeneous regions of squid axons. J Physiol 336:285-300 [PubMed]

Palay SL, Sotelo C, Peters A, Orkand PM (1968) The axon hillock and the initial segment. J Cell Biol 38:193-201 [PubMed]

Rapp M, Yarom Y, Segev I (1996) Modeling back propagating action potential in weakly excitable dendrites of neocortical pyramidal cells. Proc Natl Acad Sci U S A 93:11985-90 [PubMed]

Rasband MN, Trimmer JS, Peles E, Levinson SR, Shrager P (2000) K+ channel distribution and clustering in developing and hypomyelinated axons of the optic nerve. J Neurocytol 28:319-31 [PubMed]

Regehr WG, Armstrong CM (1994) Dendritic function. Where does it all begin? Curr Biol 4:436-9 [PubMed]

Shadlen MN, Newsome WT (1998) The variable discharge of cortical neurons: implications for connectivity, computation, and information coding. J Neurosci 18:3870-96 [Journal] [PubMed]

Spruston N, Schiller Y, Stuart G, Sakmann B (1995) Activity-dependent action potential invasion and calcium influx into hippocampal CA1 dendrites. Science 268:297-300 [PubMed]

Stuart G, Schiller J, Sakmann B (1997) Action potential initiation and propagation in rat neocortical pyramidal neurons. J Physiol 505 ( Pt 3):617-32 [PubMed]

Stuart GJ, Sakmann B (1994) Active propagation of somatic action potentials into neocortical pyramidal cell dendrites. Nature 367:69-72 [PubMed]

Svoboda K, Denk W, Kleinfeld D, Tank DW (1997) In vivo dendritic calcium dynamics in neocortical pyramidal neurons. Nature 385:161-5 [PubMed]

Turner RW, Meyers DE, Richardson TL, Barker JL (1991) The site for initiation of action potential discharge over the somatodendritic axis of rat hippocampal CA1 pyramidal neurons. J Neurosci 11:2270-80 [PubMed]

Zecevic D (1996) Multiple spike-initiation zones in single neurons revealed by voltage-sensitive dyes. Nature 381:322-5 [PubMed]

Arhem P, Klement G, Blomberg C (2006) Channel density regulation of firing patterns in a cortical neuron model. Biophys J 90:4392-404 [PubMed]

Ashida G, Abe K, Funabiki K, Konishi M (2007) Passive soma facilitates submillisecond coincidence detection in the owl's auditory system. J Neurophysiol 97:2267-82 [PubMed]

Bahl A, Stemmler MB, Herz AV, Roth A (2012) Automated optimization of a reduced layer 5 pyramidal cell model based on experimental data. J Neurosci Methods 210:22-34 [Journal] [PubMed]

   A set of reduced models of layer 5 pyramidal neurons (Bahl et al. 2012) [Model]

Bianchi D, Marasco A, Limongiello A, Marchetti C, Marie H, Tirozzi B, Migliore M (2012) On the mechanisms underlying the depolarization block in the spiking dynamics of CA1 pyramidal neurons J Comput. Neurosci. 33:207-25 [Journal] [PubMed]

   CA1 pyramidal neuron: depolarization block (Bianchi et al. 2012) [Model]

Carnevale NT, Morse TM (1996-2009) Research reports that have used NEURON Web published citations at the NEURON website [Journal]

Clark BA, Monsivais P, Branco T, London M, Hausser M (2005) The site of action potential initiation in cerebellar Purkinje neurons. Nat Neurosci 8:137-9 [PubMed]

Fleidervish IA, Lasser-Ross N, Gutnick MJ, Ross WN (2010) Na+ imaging reveals little difference in action potential-evoked Na+ influx between axon and soma. Nat Neurosci 13:852-60 [Journal] [PubMed]

   Action potential-evoked Na+ influx are similar in axon and soma (Fleidervish et al. 2010) [Model]

Foust AJ, Yu Y, Popovic M, Zecevic D, McCormick DA (2011) Somatic membrane potential and Kv1 channels control spike repolarization in cortical axon collaterals and presynaptic boutons The Journal of Neuroscience 31(43):15490-15498 [Journal] [PubMed]

   Spike repolarization in axon collaterals (Foust et al. 2011) [Model]

Gasparini S, Migliore M, Magee JC (2004) On the initiation and propagation of dendritic spikes in CA1 pyramidal neurons. J Neurosci 24:11046-11056 [Journal] [PubMed]

   CA1 pyramidal neuron: dendritic spike initiation (Gasparini et al 2004) [Model]

Gold C, Henze DA, Koch C (2007) Using Extracellular Action Potential Recordings to Tune Compartmental Models. Journal of Computational Neuroscience 23:39-58 [Journal] [PubMed]

   Extracellular Action Potential Simulations (Gold et al 2007) [Model]

Gold C, Henze DA, Koch C, Buzsaki G (2006) On the origin of the extracellular action potential waveform: A modeling study. J Neurophysiol 95:3113-28 [Journal] [PubMed]

   Extracellular Action Potential Simulations (Gold et al 2007) [Model]

Golomb D, Yue C, Yaari Y (2006) Contribution of persistent Na+current and M-type K+ current to somatic bursting in CA1 pyramidal cells: combined experimental and modeling study J Neurophysiol 96(4):1912-26 [Journal] [PubMed]

   CA1 pyramidal cell: I_NaP and I_M contributions to somatic bursting (Golomb et al 2006) [Model]

Hay E, Hill S, Schurmann F, Markram H, Segev I (2011) Models of neocortical layer 5b pyramidal cells capturing a wide range of dendritic and perisomatic active properties. PLoS Comput Biol 7:e1002107 [Journal] [PubMed]

   Layer V pyramidal cell model with reduced morphology (Mäki-Marttunen et al 2017) [Model]
   Cortical Layer 5b pyr. cell with [Na+]i mechanisms, from Hay et al 2011 (Zylbertal et al 2017) [Model]
   L5b PC model constrained for BAC firing and perisomatic current step firing (Hay et al., 2011) [Model]

Hay E, Schurmann F, Markram H, Segev I (2013) Preserving Axo-somatic Spiking Features Despite Diverse Dendritic Morphology. J Neurophysiol 109(12):2972-81 [Journal] [PubMed]

   Preserving axosomatic spiking features despite diverse dendritic morphology (Hay et al., 2013) [Model]

Hines ML, Carnevale NT (2003) Personal Communication of NEURON bibliography

Hu W, Tian C, Li T, Yang M, Hou H, Shu Y (2009) Distinct contributions of Na(v)1.6 and Na(v)1.2 in action potential initiation and backpropagation. Nat Neurosci 12:996-1002 [Journal] [PubMed]

   Action Potential initiation and backpropagation in Neocortical L5 Pyramidal Neuron (Hu et al. 2009) [Model]

Huss ME, Lansner A, Wallen P, El Manira A, Grillner S, Hellgren Kotaleski J (2007) Roles of ionic currents in lamprey CPG neurons: a modeling study. J Neurophysiol 97:2696-2711 [PubMed]

   Lamprey spinal CPG neuron (Huss et al. 2007) [Model]

Keren N, Peled N, Korngreen A (2005) Constraining compartmental models using multiple voltage recordings and genetic algorithms. J Neurophysiol 94:3730-42 [Journal] [PubMed]

Kole MH, Ilschner SU, Kampa BM, Williams SR, Ruben PC, Stuart GJ (2008) Action potential generation requires a high sodium channel density in the axon initial segment. Nat Neurosci 11:178-86 [Journal] [PubMed]

   Na+ channel dependence of AP initiation in cortical pyramidal neuron (Kole et al. 2008) [Model]

Lee DC, Jensen AL, Schiefer MA, Morgan CW, Grill WM (2005) Structural mechanisms to produce differential dendritic gains. Brain Res 1033:117-27 [Journal] [PubMed]

Liu Z, Ren J, Murphy TH (2003) Decoding of synaptic voltage waveforms by specific classes of recombinant high-threshold Ca(2+) channels. J Physiol 553:473-88 [PubMed]

McCormick DA, Shu Y, Yu Y (2007) Hodgkin and Huxley model still standing? Nature 445:E1-E2 [Journal] [PubMed]

   AP back-prop. explains threshold variability and rapid rise (McCormick et al. 2007, Yu et al. 2008) [Model]

Meeks JP, Mennerick S (2007) Action potential initiation and propagation in CA3 pyramidal axons. J Neurophysiol 97:3460-72 [PubMed]

Mercer JN, Chan CS, Tkatch T, Held J, Surmeier DJ (2007) Nav1.6 sodium channels are critical to pacemaking and fast spiking in globus pallidus neurons. J Neurosci 27:13552-66 [Journal] [PubMed]

   Nav1.6 sodium channel model in globus pallidus neurons (Mercer et al. 2007) [Model]

Oz P, Huang M, Wolf F (2015) Action potential initiation in a multi-compartmental model with cooperatively gating Na channels in the axon initial segment. J Comput Neurosci 39:63-75 [Journal] [PubMed]

   MCCAIS model (multicompartmental cooperative AIS) (Öz et al 2015) [Model]

Platkiewicz J, Brette R (2010) A threshold equation for action potential initiation. PLoS Comput Biol 6:e1000850 [Journal] [PubMed]

   A threshold equation for action potential initiation (Platkiewicz & Brette 2010) [Model]

Royeck M, Horstmann MT, Remy S, Reitze M, Yaari Y, Beck H (2008) Role of Axonal NaV1.6 Sodium Channels in Action Potential Initiation of CA1 Pyramidal Neurons. J Neurophysiol [Journal] [PubMed]

   Axonal NaV1.6 Sodium Channels in AP Initiation of CA1 Pyramidal Neurons (Royeck et al. 2008) [Model]

Saraga F, Wu CP, Zhang L, Skinner FK (2003) Active Dendrites and Spike Propagation in Multi-compartment Models of Oriens-Lacunosum/Moleculare Hippocampal Interneurons. J Physiol 552(3):673-689 [Journal] [PubMed]

   Active dendrites and spike propagation in a hippocampal interneuron (Saraga et al 2003) [Model]

Schaefer AT, Helmstaedter M, Schmitt AC, Bar-Yehuda D, Almog M, Ben-Porat H, Sakmann B, Korng (2007) Dendritic voltage-gated K+ conductance gradient in pyramidal neurones of neocortical layer 5B from rats. J Physiol 579:737-52 [PubMed]

   Correcting space clamp in dendrites (Schaefer et al. 2003 and 2007) [Model]

Schmidt-Hieber C, Bischofberger J (2010) Fast Sodium Channel Gating Supports Localized and Efficient Axonal Action Potential Initiation J. Neurosci. 30(30):10233-10242 [Journal] [PubMed]

   Fast sodium channel gating in mossy fiber axons (Schmidt-Hieber et al. 2010) [Model]

Shu Y, Duque A, Yu Y, Haider B, McCormick DA (2007) Properties of action-potential initiation in neocortical pyramidal cells: evidence from whole cell axon recordings. J Neurophysiol 97:746-60 [Journal] [PubMed]

   Intracortical synaptic potential modulation by presynaptic somatic potential (Shu et al. 2006, 2007) [Model]

Spirou GA, Rager J, Manis PB (2005) Convergence of auditory-nerve fiber projections onto globular bushy cells. Neuroscience 136:843-63 [PubMed]

Williams SR, Stuart GJ (2003) Voltage- and site-dependent control of the somatic impact of dendritic IPSPs. J Neurosci 23:7358-67 [PubMed]

Wilmes KA, Sprekeler H, Schreiber S (2016) Inhibition as a Binary Switch for Excitatory Plasticity in Pyramidal Neurons. PLoS Comput Biol 12:e1004768 [Journal] [PubMed]

   Inhibition of bAPs and Ca2+ spikes in a multi-compartment pyramidal neuron model (Wilmes et al 2016) [Model]

Yu Y, Shu Y, McCormick DA (2008) Cortical action potential backpropagation explains spike threshold variability and rapid-onset kinetics. J Neurosci 28:7260-72 [Journal] [PubMed]

   AP back-prop. explains threshold variability and rapid rise (McCormick et al. 2007, Yu et al. 2008) [Model]

Zylbertal A, Kahan A, Ben-Shaul Y, Yarom Y, Wagner S (2015) Prolonged Intracellular Na+ Dynamics Govern Electrical Activity in Accessory Olfactory Bulb Mitral Cells PLOS Biology 13(12):e1002319 [Journal]

   AOB mitral cell: persistent activity without feedback (Zylbertal et al., 2015) [Model]

Zylbertal A, Yarom Y, Wagner S (2017) The Slow Dynamics of Intracellular Sodium Concentration Increase the Time Window of Neuronal Integration: A Simulation Study Front. Comput. Neurosci. 11(85):1-16 [Journal]

   Cortical Layer 5b pyr. cell with [Na+]i mechanisms, from Hay et al 2011 (Zylbertal et al 2017) [Model]

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