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Gulledge AT, Carnevale NT, Stuart GJ (2012) Electrical advantages of dendritic spines PLoS One. 7(4):e36007[PubMed]

References and models cited by this paper

References and models that cite this paper

Araya R, Jiang J, Eisenthal KB, Yuste R (2006) The spine neck filters membrane potentials. Proc Natl Acad Sci U S A 103:17961-6 [PubMed]

Araya R, Nikolenko V, Eisenthal KB, Yuste R (2007) Sodium channels amplify spine potentials. Proc Natl Acad Sci U S A 104:12347-52 [PubMed]

Arellano JI, Benavides-Piccione R, Defelipe J, Yuste R (2007) Ultrastructure of dendritic spines: correlation between synaptic and spine morphologies. Front Neurosci 1:131-43 [PubMed]

Bekkers JM (2000) Distribution and activation of voltage-gated potassium channels in cell-attached and outside-out patches from large layer 5 cortical pyramidal neurons of the rat. J Physiol 525 Pt 3:611-20 [PubMed]

Berger T, Larkum ME, Luscher HR (2001) High I(h) channel density in the distal apical dendrite of layer V pyramidal cells increases bidirectional attenuation of EPSPs. J Neurophysiol 85:855-68 [Journal] [PubMed]

Bloodgood BL, Giessel AJ, Sabatini BL (2009) Biphasic synaptic Ca influx arising from compartmentalized electrical signals in dendritic spines. PLoS Biol 7:e1000190-3 [PubMed]

Bloodgood BL, Sabatini BL (2005) Neuronal activity regulates diffusion across the neck of dendritic spines. Science 310:866-9 [PubMed]

Bloodgood BL, Sabatini BL (2007) Nonlinear regulation of unitary synaptic signals by CaV(2.3) voltage-sensitive calcium channels located in dendritic spines. Neuron 53:249-60 [PubMed]

Branco T, Hausser M (2011) Synaptic integration gradients in single cortical pyramidal cell dendrites. Neuron 69:885-92 [Journal] [PubMed]

   Dendritic Discrimination of Temporal Input Sequences (Branco et al. 2010) [Model]

Carnevale NT, Hines ML (2006) The NEURON Book

CHANG HT (1952) Cortical neurons with particular reference to the apical dendrites. Cold Spring Harb Symp Quant Biol 17:189-202 [PubMed]

Chklovskii DB (2004) Synaptic connectivity and neuronal morphology: two sides of the same coin. Neuron 43:609-17 [PubMed]

Dunaevsky A, Tashiro A, Majewska A, Mason C, Yuste R (1999) Developmental regulation of spine motility in the mammalian central nervous system. Proc Natl Acad Sci U S A 96:13438-43 [PubMed]

Faber ES, Delaney AJ, Sah P (2005) SK channels regulate excitatory synaptic transmission and plasticity in the lateral amygdala. Nat Neurosci 8:635-41 [PubMed]

Fifková E, Anderson CL (1981) Stimulation-induced changes in dimensions of stalks of dendritic spines in the dentate molecular layer. Exp Neurol 74:621-7 [PubMed]

Fischer M, Kaech S, Knutti D, Matus A (1998) Rapid actin-based plasticity in dendritic spines. Neuron 20:847-54 [PubMed]

Grunditz A, Holbro N, Tian L, Zuo Y, Oertner TG (2008) Spine Neck Plasticity Controls Postsynaptic Calcium Signals through Electrical Compartmentalization J Neurosci 28(50):13457-13466 [Journal] [PubMed]

   Spine neck plasticity controls postsynaptic calcium signals (Grunditz et al. 2008) [Model]

Guidotti A, Pesold C, Costa E (2000) New neurochemical markers for psychosis: a working hypothesis of their operation. Neurochem Res 25:1207-18 [PubMed]

Gulledge AT, Kampa BM, Stuart GJ (2005) Synaptic integration in dendritic trees. J Neurobiol 64:75-90 [PubMed]

Harris KM, Jensen FE, Tsao B (1992) Three-dimensional structure of dendritic spines and synapses in rat hippocampus (CA1) at postnatal day 15 and adult ages: implications for the maturation of synaptic physiology and long-term potentiation. J Neurosci 12:2685-705 [PubMed]

Harris KM, Stevens JK (1989) Dendritic spines of CA 1 pyramidal cells in the rat hippocampus: serial electron microscopy with reference to their biophysical characteristics. J Neurosci 9:2982-97 [PubMed]

Hines ML, Carnevale NT (2001) NEURON: a tool for neuroscientists. Neuroscientist 7:123-35 [Journal] [PubMed]

   Spatial gridding and temporal accuracy in NEURON (Hines and Carnevale 2001) [Model]

Holbro N, Grunditz A, Wiegert JS, Oertner TG (2010) AMPA receptors gate spine Ca(2+) transients and spike-timing-dependent potentiation. Proc Natl Acad Sci U S A 107:15975-80 [PubMed]

Isope P, Murphy TH (2005) Low threshold calcium currents in rat cerebellar Purkinje cell dendritic spines are mediated by T-type calcium channels. J Physiol 562:257-69 [Journal] [PubMed]

Jaffe DB, Carnevale NT (1999) Passive normalization of synaptic integration influenced by dendritic architecture. J Neurophysiol 82:3268-85 [Journal] [PubMed]

Jaslove SW (1992) The integrative properties of spiny distal dendrites. Neuroscience 47:495-519 [PubMed]

Kasai H, Matsuzaki M, Noguchi J, Yasumatsu N, Nakahara H (2003) Structure-stability-function relationships of dendritic spines. Trends Neurosci 26:360-8

Katz Y, Menon V, Nicholson DA, Geinisman Y, Kath WL, Spruston N (2009) Synapse distribution suggests a two-stage model of dendritic integration in CA1 pyramidal neurons. Neuron 63:171-7 [Journal] [PubMed]

   A two-stage model of dendritic integration in CA1 pyramidal neurons (Katz et al. 2009) [Model]

Kawato M, Tsukahara N (1983) Theoretical study on electrical properties of dendritic spines. J Theor Biol 103:507-22 [PubMed]

Kawato M, Tsukahara N (1984) Electrical properties of dendritic spines with bulbous end terminals. Biophys J 46:155-66 [PubMed]

Koch C, Zador A (1993) The function of dendritic spines: devices subserving biochemical rather than electrical compartmentalization. J Neurosci 13:413-22 [PubMed]

Kole MH, Hallermann S, Stuart GJ (2006) Single Ih channels in pyramidal neuron dendrites: properties, distribution, and impact on action potential output. J Neurosci 26:1677-87 [Journal] [PubMed]

   Stochastic Ih and Na-channels in pyramidal neuron dendrites (Kole et al 2006) [Model]

Kole MH, Ilschner SU, Kampa BM, Williams SR, Ruben PC, Stuart GJ (2008) Action potential generation requires a high sodium channel density in the axon initial segment. Nat Neurosci 11:178-86 [Journal] [PubMed]

   Na+ channel dependence of AP initiation in cortical pyramidal neuron (Kole et al. 2008) [Model]

Kopec CD, Li B, Wei W, Boehm J, Malinow R (2006) Glutamate receptor exocytosis and spine enlargement during chemically induced long-term potentiation. J Neurosci 26:2000-9 [Journal] [PubMed]

Korkotian E, Segal M (2007) Spatially confined diffusion of calcium in dendrites of hippocampal neurons revealed by flash photolysis of caged calcium. Cell Calcium 40:441-9 [PubMed]

Korkotian E, Segal M (2007) Morphological constraints on calcium dependent glutamate receptor trafficking into individual dendritic spine. Cell Calcium 42:41-57 [PubMed]

Korngreen A, Sakmann B (2000) Voltage-gated K+ channels in layer 5 neocortical pyramidal neurones from young rats: subtypes and gradients. J Physiol 525 Pt 3:621-39 [PubMed]

   Pyramidal Neuron Deep: K+ kinetics (Korngreen, Sakmann 2000) [Model]

Lamprecht R, LeDoux J (2004) Structural plasticity and memory. Nat Rev Neurosci 5:45-54 [Journal] [PubMed]

Lang C, Barco A, Zablow L, Kandel ER, Siegelbaum SA, Zakharenko SS (2004) Transient expansion of synaptically connected dendritic spines upon induction of hippocampal long-term potentiation. Proc Natl Acad Sci U S A 101:16665-70 [PubMed]

Larkum ME, Nevian T, Sandler M, Polsky A, Schiller J (2009) Synaptic integration in tuft dendrites of layer 5 pyramidal neurons: a new unifying principle. Science 325:756-60 [Journal] [PubMed]

   Synaptic integration in tuft dendrites of layer 5 pyramidal neurons (Larkum et al. 2009) [Model]

Lee SJ, Escobedo-Lozoya Y, Szatmari EM, Yasuda R (2009) Activation of CaMKII in single dendritic spines during long-term potentiation. Nature 458:299-304 [PubMed]

Leitch B, Szostek A, Lin R, Shevtsova O (2009) Subcellular distribution of L-type calcium channel subtypes in rat hippocampal neurons. Neuroscience 164:641-57 [Journal] [PubMed]

Lester RA, Clements JD, Westbrook GL, Jahr CE (1990) Channel kinetics determine the time course of NMDA receptor-mediated synaptic currents. Nature 346:565-7 [PubMed]

Lorincz A, Nusser Z (2010) Molecular identity of dendritic voltage-gated sodium channels. Science 328:906-9 [PubMed]

Magee JC (1998) Dendritic hyperpolarization-activated currents modify the integrative properties of hippocampal CA1 pyramidal neurons. J Neurosci 18:7613-24 [PubMed]

Mainen ZF, Sejnowski TJ (1996) Influence of dendritic structure on firing pattern in model neocortical neurons. Nature 382:363-6 [Journal] [PubMed]

   Pyramidal Neuron Deep, Superficial; Aspiny, Stellate (Mainen and Sejnowski 1996) [Model]

Martone ME, Gupta A, Wong M, Qian X, Sosinsky G, Ludäscher B, Ellisman MH (2002) A cell-centered database for electron tomographic data. J Struct Biol 138:145-55 [PubMed]

Matsuzaki M, Ellis-Davies GC, Nemoto T, Miyashita Y, Iino M, Kasai H (2001) Dendritic spine geometry is critical for AMPA receptor expression in hippocampal CA1 pyramidal neurons. Nat Neurosci 4:1086-92 [PubMed]

Matsuzaki M, Honkura N, Ellis-Davies GC, Kasai H (2004) Structural basis of long-term potentiation in single dendritic spines. Nature 429:761-6 [PubMed]

Muller W, Connor JA (1991) Dendritic spines as individual neuronal compartments for synaptic Ca2+ responses. Nature 354:73-6 [PubMed]

Nevian T, Larkum ME, Polsky A, Schiller J (2007) Properties of basal dendrites of layer 5 pyramidal neurons: a direct patch-clamp recording study. Nat Neurosci 10:206-14 [Journal] [PubMed]

   Dendritic Na+ spike initiation and backpropagation of APs in active dendrites (Nevian et al. 2007) [Model]

Ngo-Anh TJ, Bloodgood BL, Lin M, Sabatini BL, Maylie J, Adelman JP (2005) SK channels and NMDA receptors form a Ca2+-mediated feedback loop in dendritic spines. Nat Neurosci 8:642-9 [PubMed]

Nicholson DA, Trana R, Katz Y, Kath WL, Spruston N, Geinisman Y (2006) Distance-dependent differences in synapse number and AMPA receptor expression in hippocampal CA1 pyramidal neurons. Neuron 50:431-42 [Journal] [PubMed]

Oertner TG (2009) How do synapses measure milliseconds? Front Comput Neurosci 3:7 [Journal] [PubMed]

Okamoto K, Nagai T, Miyawaki A, Hayashi Y (2004) Rapid and persistent modulation of actin dynamics regulates postsynaptic reorganization underlying bidirectional plasticity. Nat Neurosci 7:1104-12 [Journal] [PubMed]

Otmakhov N, Tao-Cheng JH, Carpenter S, Asrican B, Dosemeci A, Reese TS, Lisman J (2004) Persistent accumulation of calcium/calmodulin-dependent protein kinase II in dendritic spines after induction of NMDA receptor-dependent chemical long-term potentiation. J Neurosci 24:9324-31 [Journal] [PubMed]

Palmer LM, Stuart GJ (2009) Membrane potential changes in dendritic spines during action potentials and synaptic input. J Neurosci 29:6897-903 [Journal] [PubMed]

   Membrane potential changes in dendritic spines during APs and synaptic input (Palmer & Stuart 2009) [Model]

Peterka DS, Takahashi H, Yuste R (2011) Imaging voltage in neurons. Neuron 69:9-21 [Journal] [PubMed]

Peters A, Kaiserman-Abramof IR (1970) The small pyramidal neuron of the rat cerebral cortex. The perikaryon, dendrites and spines. Am J Anat 127:321-55 [PubMed]

Rall W (1974) Dendritic spines, synaptic potency and neuronal plasticity Cellular mechanisms subserving changes in neuronal activity, Woody CD:Brown KA:Crow TJ:Knispel JD, ed. pp.13

Ramon y Cajal S (1899) Regias y consejos sobre investigacion biologica

Rinzel J, Rall W (1974) Transient response in a dendritic neuron model for current injected at one branch. Biophys J 14:759-90 [PubMed]

Roth A, Hausser M (2001) Compartmental models of rat cerebellar Purkinje cells based on simultaneous somatic and dendritic patch-clamp recordings. J Physiol 535:445-72 [PubMed]

Sabatini BL, Oertner TG, Svoboda K (2002) The life cycle of Ca(2+) ions in dendritic spines. Neuron 33:439-52 [PubMed]

Sabatini BL, Svoboda K (2000) Analysis of calcium channels in single spines using optical fluctuation analysis. Nature 408:589-93 [PubMed]

Schiller J, Major G, Koester HJ, Schiller Y (2000) NMDA spikes in basal dendrites of cortical pyramidal neurons. Nature 404:285-9 [PubMed]

Schmidt-Hieber C, Jonas P, Bischofberger J (2007) Subthreshold dendritic signal processing and coincidence detection in dentate gyrus granule cells. J Neurosci 27:8430-41 [Journal] [PubMed]

   Dentate gyrus granule cell: subthreshold signal processing (Schmidt-Hieber et al. 2007) [Model]

Segev I, Friedman A, White EL, Gutnick MJ (1995) Electrical consequences of spine dimensions in a model of a cortical spiny stellate cell completely reconstructed from serial thin sections. J Comput Neurosci 2:117-30 [Journal] [PubMed]

Segev I, London M (2000) Untangling dendrites with quantitative models. Science 290:744-50 [PubMed]

Spruston N (2008) Pyramidal neurons: dendritic structure and synaptic integration. Nat Rev Neurosci 9:206-21 [PubMed]

Stuart G, Spruston N (1998) Determinants of voltage attenuation in neocortical pyramidal neuron dendrites. J Neurosci 18:3501-10 [PubMed]

   Pyramidal Neuron Deep: attenuation in dendrites (Stuart, Spruston 1998) [Model]

Stuart GJ, Sakmann B (1994) Active propagation of somatic action potentials into neocortical pyramidal cell dendrites. Nature 367:69-72 [PubMed]

Svoboda K, Tank DW, Denk W (1996) Direct measurement of coupling between dendritic spines and shafts. Science 272:716-9 [PubMed]

Tanaka J, Horiike Y, Matsuzaki M, Miyazaki T, Ellis-Davies GC, Kasai H (2008) Protein synthesis and neurotrophin-dependent structural plasticity of single dendritic spines. Science 319:1683-7 [PubMed]

Turrigiano GG, Nelson SB (2004) Homeostatic plasticity in the developing nervous system. Nat Rev Neurosci 5:97-107 [PubMed]

Wilson CJ (1984) Passive cable properties of dendritic spines and spiny neurons. J Neurosci 4:281-97 [PubMed]

Yuste R, Denk W (1995) Dendritic spines as basic functional units of neuronal integration. Nature 375:682-4 [PubMed]

Acker CD, Hoyos E, Loew LM (2016) EPSPs Measured in Proximal Dendritic Spines of Cortical Pyramidal Neurons. eNeuro [Journal] [PubMed]

Behabadi BF, Mel BW (2014) Mechanisms underlying subunit independence in pyramidal neuron dendrites. Proc Natl Acad Sci U S A 111:498-503 [Journal] [PubMed]

   Mechanisms underlying subunit independence in pyramidal neuron dendrites (Behabadi and Mel 2014) [Model]

Kubota Y, Kondo S, Nomura M, Hatada S, Yamaguchi N, Mohamed AA, Karube F, Lübke J, Kawaguchi (2015) Functional effects of distinct innervation styles of pyramidal cells by fast spiking cortical interneurons. Elife [Journal] [PubMed]

   A Layer V CCS type pyramidal cell, inhibitory synapse current conduction (Kubota Y et al., 2015) [Model]

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