Citation Relationships



Meza RC, López-Jury L, Canavier CC, Henny P (2018) Role of the Axon Initial Segment in the Control of Spontaneous Frequency of Nigral Dopaminergic Neurons In Vivo. J Neurosci 38:733-744 [PubMed]

   Role of the AIS in the control of spontaneous frequency of dopaminergic neurons (Meza et al 2017)

References and models cited by this paper

References and models that cite this paper

Ascoli GA (2006) Mobilizing the base of neuroscience data: the case of neuronal morphologies. Nat Rev Neurosci 7:318-24 [Journal] [PubMed]

Bender KJ, Trussell LO (2009) Axon initial segment Ca2+ channels influence action potential generation and timing. Neuron 61:259-71 [Journal] [PubMed]

Bender KJ, Trussell LO (2012) The physiology of the axon initial segment. Annu Rev Neurosci 35:249-65 [Journal] [PubMed]

Blythe SN, Wokosin D, Atherton JF, Bevan MD (2009) Cellular mechanisms underlying burst firing in substantia nigra dopamine neurons. J Neurosci 29:15531-41 [Journal] [PubMed]

Brown MT, Henny P, Bolam JP, Magill PJ (2009) Activity of neurochemically heterogeneous dopaminergic neurons in the substantia nigra during spontaneous and driven changes in brain state. J Neurosci 29:2915-25 [Journal] [PubMed]

Canavier CC, Evans RC, Oster AM, Pissadaki EK, Drion G, Kuznetsov AS, Gutkin BS (2016) Implications of cellular models of dopamine neurons for disease. J Neurophysiol 116:2815-2830 [Journal] [PubMed]

Canavier CC, Landry RS (2006) An increase in AMPA and a decrease in SK conductance increase burst firing by different mechanisms in a model of a dopamine neuron in vivo. J Neurophysiol 96:2549-63 [Journal] [PubMed]

   Differential modulation of pattern and rate in a dopamine neuron model (Canavier and Landry 2006) [Model]

de Vrind V, Scuvée-Moreau J, Drion G, Hmaied C, Philippart F, Engel D, Seutin V (2016) Interactions between calcium channels and SK channels in midbrain dopamine neurons and their impact on pacemaker regularity: Contrasting roles of N- and L-type channels. Eur J Pharmacol 788:274-279 [Journal] [PubMed]

Durante P, Cardenas CG, Whittaker JA, Kitai ST, Scroggs RS (2004) Low-threshold L-type calcium channels in rat dopamine neurons. J Neurophysiol 91:1450-4 [Journal] [PubMed]

Evans MD, Dumitrescu AS, Kruijssen DLH, Taylor SE, Grubb MS (2015) Rapid Modulation of Axon Initial Segment Length Influences Repetitive Spike Firing. Cell Rep 13:1233-1245 [Journal] [PubMed]

Fahn S (2008) The history of dopamine and levodopa in the treatment of Parkinson's disease. Mov Disord 23 Suppl 3:S497-508 [Journal] [PubMed]

Fellous J-M,Canavier C,Hasselmo ME (2015) Neuromodulation From neuron to cognition via computational neuroscience, Arbib M, ed.

Fu Y, Yuan Y, Halliday G, Rusznák Z, Watson C, Paxinos G (2012) A cytoarchitectonic and chemoarchitectonic analysis of the dopamine cell groups in the substantia nigra, ventral tegmental area, and retrorubral field in the mouse. Brain Struct Funct 217:591-612 [Journal] [PubMed]

Galiano MR, Jha S, Ho TS, Zhang C, Ogawa Y, Chang KJ, Stankewich MC, Mohler PJ, Rasband MN (2012) A distal axonal cytoskeleton forms an intra-axonal boundary that controls axon initial segment assembly. Cell 149:1125-39 [Journal] [PubMed]

Gentet LJ, Williams SR (2007) Dopamine gates action potential backpropagation in midbrain dopaminergic neurons. J Neurosci 27:1892-901 [Journal] [PubMed]

Gonzalez A, Moya-Alvarado G, Gonzalez-Billaut C, Bronfman FC (2016) Cellular and molecular mechanisms regulating neuronal growth by brain-derived neurotrophic factor. Cytoskeleton (Hoboken) 73:612-628 [Journal] [PubMed]

González-Cabrera C, Meza R, Ulloa L, Merino-Sepúlveda P, Luco V, Sanhueza A, Oñate-Ponce A, Bolam JP, Henny P (2017) Characterization of the axon initial segment of mice substantia nigra dopaminergic neurons. J Comp Neurol 525:3529-3542 [Journal] [PubMed]

Goto Y, Otani S, Grace AA (2007) The Yin and Yang of dopamine release: a new perspective. Neuropharmacology 53:583-7 [Journal] [PubMed]

Grace AA (1995) The tonic/phasic model of dopamine system regulation: its relevance for understanding how stimulant abuse can alter basal ganglia function. Drug Alcohol Depend 37:111-29 [PubMed]

Grace AA (2016) Dysregulation of the dopamine system in the pathophysiology of schizophrenia and depression. Nat Rev Neurosci 17:524-32 [Journal] [PubMed]

Grace AA, Bunney BS (1983) Intracellular and extracellular electrophysiology of nigral dopaminergic neurons--2. Action potential generating mechanisms and morphological correlates. Neuroscience 10:317-31 [PubMed]

Grace AA, Bunney BS (1984) The control of firing pattern in nigral dopamine neurons: burst firing. J Neurosci 4:2877-90 [PubMed]

Grubb MS, Burrone J (2010) Activity-dependent relocation of the axon initial segment fine-tunes neuronal excitability. Nature 465:1070-4 [Journal] [PubMed]

Grubb MS, Burrone J (2010) Building and maintaining the axon initial segment. Curr Opin Neurobiol 20:481-8 [Journal] [PubMed]

Gulledge AT, Bravo JJ (2016) Neuron Morphology Influences Axon Initial Segment Plasticity. eNeuro [Journal] [PubMed]

Guo SL, Tan GH, Li S, Cheng XW, Zhou Y, Jia YF, Xiong H, Tao J, Xiong ZQ (2012) Serum inducible kinase is a positive regulator of cortical dendrite development and is required for BDNF-promoted dendritic arborization. Cell Res 22:387-98 [Journal] [PubMed]

Guzman JN, Sánchez-Padilla J, Chan CS, Surmeier DJ (2009) Robust pacemaking in substantia nigra dopaminergic neurons. J Neurosci 29:11011-9 [Journal] [PubMed]

Hage TA, Khaliq ZM (2015) Tonic firing rate controls dendritic Ca2+ signaling and synaptic gain in substantia nigra dopamine neurons. J Neurosci 35:5823-36 [Journal] [PubMed]

Hahn J, Kullmann PH, Horn JP, Levitan ES (2006) D2 autoreceptors chronically enhance dopamine neuron pacemaker activity. J Neurosci 26:5240-7 [Journal] [PubMed]

Hamada MS, Goethals S, de Vries SI, Brette R, Kole MH (2016) Covariation of axon initial segment location and dendritic tree normalizes the somatic action potential. Proc Natl Acad Sci U S A 113:14841-14846 [Journal] [PubMed]

Hasselmo ME, Giocomo LM, Zilli EA (2007) Grid cell firing may arise from interference of theta frequency membrane potential oscillations in single neurons. Hippocampus 17:1252-71 [Journal] [PubMed]

Häusser M, Stuart G, Racca C, Sakmann B (1995) Axonal initiation and active dendritic propagation of action potentials in substantia nigra neurons. Neuron 15:637-47 [PubMed]

Henny P, Brown MT, Micklem BR, Magill PJ, Bolam JP (2014) Stereological and ultrastructural quantification of the afferent synaptome of individual neurons. Brain Struct Funct 219:631-40 [Journal] [PubMed]

Henny P, Brown MT, Northrop A, Faunes M, Ungless MA, Magill PJ, Bolam JP (2012) Structural correlates of heterogeneous in vivo activity of midbrain dopaminergic neurons. Nat Neurosci 15:613-9 [Journal] [PubMed]

Hines ML, Carnevale NT (1997) The NEURON simulation environment. Neural Comput 9:1179-209 [PubMed]

Hu W, Tian C, Li T, Yang M, Hou H, Shu Y (2009) Distinct contributions of Na(v)1.6 and Na(v)1.2 in action potential initiation and backpropagation. Nat Neurosci 12:996-1002 [Journal] [PubMed]

   Action Potential initiation and backpropagation in Neocortical L5 Pyramidal Neuron (Hu et al. 2009) [Model]

Jang J, Um KB, Jang M, Kim SH, Cho H, Chung S, Kim HJ, Park MK (2014) Balance between the proximal dendritic compartment and the soma determines spontaneous firing rate in midbrain dopamine neurons. J Physiol 592:2829-44 [Journal] [PubMed]

Jenkins SM, Bennett V (2001) Ankyrin-G coordinates assembly of the spectrin-based membrane skeleton, voltage-gated sodium channels, and L1 CAMs at Purkinje neuron initial segments. J Cell Biol 155:739-46 [Journal] [PubMed]

Kole MH, Ilschner SU, Kampa BM, Williams SR, Ruben PC, Stuart GJ (2008) Action potential generation requires a high sodium channel density in the axon initial segment. Nat Neurosci 11:178-86 [Journal] [PubMed]

   Na+ channel dependence of AP initiation in cortical pyramidal neuron (Kole et al. 2008) [Model]

Kuba H, Oichi Y, Ohmori H (2010) Presynaptic activity regulates Na(+) channel distribution at the axon initial segment. Nature 465:1075-8 [Journal] [PubMed]

Kuznetsov AS, Kopell NJ, Wilson CJ (2006) Transient high-frequency firing in a coupled-oscillator model of the mesencephalic dopaminergic neuron. J Neurophysiol 95:932-47 [Journal] [PubMed]

   Dopaminergic cell bursting model (Kuznetsov et al 2006) [Model]

Kuznetsova AY, Huertas MA, Kuznetsov AS, Paladini CA, Canavier CC (2010) Regulation of firing frequency in a computational model of a midbrain dopaminergic neuron. J Comput Neurosci 28:389-403 [Journal] [PubMed]

   Regulation of firing frequency in a midbrain dopaminergic neuron model (Kuznetsova et al. 2010) [Model]

Liss B, Franz O, Sewing S, Bruns R, Neuhoff H, Roeper J (2001) Tuning pacemaker frequency of individual dopaminergic neurons by Kv4.3L and KChip3.1 transcription. EMBO J 20:5715-24 [Journal] [PubMed]

Lobb CJ, Wilson CJ, Paladini CA (2010) A dynamic role for GABA receptors on the firing pattern of midbrain dopaminergic neurons. J Neurophysiol 104:403-13 [Journal] [PubMed]

Mainen ZF, Joerges J, Huguenard JR, Sejnowski TJ (1995) A model of spike initiation in neocortical pyramidal neurons. Neuron 15:1427-39 [PubMed]

   Spike Initiation in Neocortical Pyramidal Neurons (Mainen et al 1995) [Model]

Michel PP, Hirsch EC, Hunot S (2016) Understanding Dopaminergic Cell Death Pathways in Parkinson Disease. Neuron 90:675-91 [Journal] [PubMed]

Paladini CA, Roeper J (2014) Generating bursts (and pauses) in the dopamine midbrain neurons. Neuroscience 282:109-21 [Journal] [PubMed]

Paxinos G,Franklin KBJ (2012) The Mouse Brain in Stereotaxic Coordinates, 4th Edition

Pinault D (1996) A novel single-cell staining procedure performed in vivo under electrophysiological control: morpho-functional features of juxtacellularly labeled thalamic cells and other central neurons with biocytin or Neurobiotin. J Neurosci Methods 65:113-36 [PubMed]

Ping HX, Shepard PD (1996) Apamin-sensitive Ca(2+)-activated K+ channels regulate pacemaker activity in nigral dopamine neurons. Neuroreport 7:809-14 [PubMed]

Pucak ML, Grace AA (1994) Evidence that systemically administered dopamine antagonists activate dopamine neuron firing primarily by blockade of somatodendritic autoreceptors. J Pharmacol Exp Ther 271:1181-92 [PubMed]

Putzier I, Kullmann PH, Horn JP, Levitan ES (2009) Cav1.3 channel voltage dependence, not Ca2+ selectivity, drives pacemaker activity and amplifies bursts in nigral dopamine neurons. J Neurosci 29:15414-9 [Journal] [PubMed]

Ramirez JM, Tryba AK, Peña F (2004) Pacemaker neurons and neuronal networks: an integrative view. Curr Opin Neurobiol 14:665-74 [Journal] [PubMed]

Remme MW, Lengyel M, Gutkin BS (2010) Democracy-independence trade-off in oscillating dendrites and its implications for grid cells. Neuron 66:429-37 [Journal] [PubMed]

Schiemann J, Schlaudraff F, Klose V, Bingmer M, Seino S, Magill PJ, Zaghloul KA, Schneider G, Liss B, Roeper J (2012) K-ATP channels in dopamine substantia nigra neurons control bursting and novelty-induced exploration. Nat Neurosci 15:1272-80 [Journal] [PubMed]

Schultz W (2007) Behavioral dopamine signals. Trends Neurosci 30:203-10 [Journal] [PubMed]

Seutin V, Massotte L, Renette MF, Dresse A (2001) Evidence for a modulatory role of Ih on the firing of a subgroup of midbrain dopamine neurons. Neuroreport 12:255-8 [PubMed]

Sulzer D, Cragg SJ, Rice ME (2016) Striatal dopamine neurotransmission: regulation of release and uptake. Basal Ganglia 6:123-148 [Journal] [PubMed]

Surmeier DJ, Mercer JN, Chan CS (2005) Autonomous pacemakers in the basal ganglia: who needs excitatory synapses anyway? Curr Opin Neurobiol 15:312-8 [Journal] [PubMed]

Vetter P, Roth A, Häusser M (2001) Propagation of action potentials in dendrites depends on dendritic morphology. J Neurophysiol 85:926-37 [Journal] [PubMed]

   Dendritica (Vetter et al 2001) [Model]

Wilson CJ, Callaway JC (2000) Coupled oscillator model of the dopaminergic neuron of the substantia nigra. J Neurophysiol 83:3084-100 [Journal] [PubMed]

Wise RA (2009) Roles for nigrostriatal--not just mesocorticolimbic--dopamine in reward and addiction. Trends Neurosci 32:517-24 [Journal] [PubMed]

Zhou D, Lambert S, Malen PL, Carpenter S, Boland LM, Bennett V (1998) AnkyrinG is required for clustering of voltage-gated Na channels at axon initial segments and for normal action potential firing. J Cell Biol 143:1295-304 [PubMed]

Zigmond MJ, Abercrombie ED, Berger TW, Grace AA, Stricker EM (1990) Compensations after lesions of central dopaminergic neurons: some clinical and basic implications. Trends Neurosci 13:290-6 [PubMed]

J?drzejewski-Szmek Z, Abrahao KP, J?drzejewska-Szmek J, Lovinger DM, Blackwell KT (2018) Parameter Optimization Using Covariance Matrix Adaptation-Evolutionary Strategy (CMA-ES), an Approach to Investigate Differences in Channel Properties Between Neuron Subtypes. Front Neuroinform 12:47 [Journal] [PubMed]

   Parameter optimization using CMA-ES (Jedrzejewski-Szmek et al 2018) [Model]

López-Jury L, Meza RC, Brown MTC, Henny P, Canavier CC (2018) Morphological and Biophysical Determinants of the Intracellular and Extracellular Waveforms in Nigral Dopaminergic Neurons: A Computational Study. J Neurosci 38:8295-8310 [Journal] [PubMed]

   Determinants of the intracellular and extracellular waveforms in DA neurons (Lopez-Jury et al 2018) [Model]

(66 refs)