Citation Relationships



Polsky A, Mel BW, Schiller J (2004) Computational subunits in thin dendrites of pyramidal cells. Nat Neurosci 7:621-7[PubMed]

   CA1 pyramidal neuron: as a 2-layer NN and subthreshold synaptic summation (Poirazi et al 2003)

References and models cited by this paper

References and models that cite this paper

Archie KA, Mel BW (2000) A model for intradendritic computation of binocular disparity. Nat Neurosci 3:54-63 [Journal] [PubMed]

   Visual Cortex Neurons: Dendritic computations (Archie, Mel 2000) [Model]

Ariav G, Polsky A, Schiller J (2003) Submillisecond precision of the input-output transformation function mediated by fast sodium dendritic spikes in basal dendrites of CA1 pyramidal neurons. J Neurosci 23:7750-8 [PubMed]

Beaulieu C, Colonnier M (1985) A laminar analysis of the number of round-asymmetrical and flat-symmetrical synapses on spines, dendritic trunks, and cell bodies in area 17 of the cat. J Comp Neurol 231:180-9 [PubMed]

Bernander O, Koch C, Douglas RJ (1994) Amplification and linearization of distal synaptic input to cortical pyramidal cells. J Neurophysiol 72:2743-53 [Journal] [PubMed]

Borg-Graham LJ, Grzywacz N (1992) A model of the direction selectivity circuit in retina: transformations by neurons singly and in concert Single Neuron Computation, McKenna T:Davis J:Zornetzer SF, ed. pp.347

Cash S, Yuste R (1999) Linear summation of excitatory inputs by CA1 pyramidal neurons. Neuron 22:383-94 [PubMed]

Cauller LJ, Connors BW (1994) Synaptic physiology of horizontal afferents to layer I in slices of rat SI neocortex. J Neurosci 14:751-62 [PubMed]

Cook EP, Johnston D (1999) Voltage-dependent properties of dendrites that eliminate location-dependent variability of synaptic input. J Neurophysiol 81:535-43 [Journal] [PubMed]

Euler T, Detwiler PB, Denk W (2002) Directionally selective calcium signals in dendrites of starburst amacrine cells. Nature 418:845-52 [PubMed]

Hausser M, Mel B (2003) Dendrites: bug or feature? Curr Opin Neurobiol 13:372-83 [PubMed]

Hausser M, Spruston N, Stuart GJ (2000) Diversity and dynamics of dendritic signaling. Science 290:739-44 [PubMed]

Johnston D, Magee JC, Colbert CM, Cristie BR (1996) Active properties of neuronal dendrites. Annu Rev Neurosci 19:165-86 [PubMed]

Kepecs A, Wang XJ, Lisman J (2002) Bursting neurons signal input slope. J Neurosci 22:9053-62 [PubMed]

Koch C, Poggio T, Torre V (1983) Nonlinear interactions in a dendritic tree: localization, timing, and role in information processing. Proc Natl Acad Sci U S A 80:2799-802 [PubMed]

Larkman AU (1991) Dendritic morphology of pyramidal neurones of the visual cortex of the rat: III. Spine distributions. J Comp Neurol 306:332-43 [PubMed]

Larkum ME, Zhu JJ, Sakmann B (1999) A new cellular mechanism for coupling inputs arriving at different cortical layers. Nature 398:338-41 [PubMed]

Magee J, Hoffman D, Colbert C, Johnston D (1998) Electrical and calcium signaling in dendrites of hippocampal pyramidal neurons. Annu Rev Physiol 60:327-46 [PubMed]

Magee JC (1999) Dendritic lh normalizes temporal summation in hippocampal CA1 neurons. Nat Neurosci 2:508-14 [PubMed]

Magee JC (2000) Dendritic integration of excitatory synaptic input. Nat Rev Neurosci 1:181-90 [PubMed]

Magee JC, Cook EP (2000) Somatic EPSP amplitude is independent of synapse location in hippocampal pyramidal neurons. Nat Neurosci 3:895-903 [PubMed]

   CA1 pyramidal neuron: Synaptic Scaling (Magee, Cook 2000) [Model]

Margulis M, Tang CM (1998) Temporal integration can readily switch between sublinear and supralinear summation. J Neurophysiol 79:2809-13 [Journal] [PubMed]

McClelland JL, Rumelhart DE (1985) Distribution memory and the representation of general and specific information J Exp Psychol Gen 114:159-197

Megias M, Emri Z, Freund TF, Gulyas AI (2001) Total number and distribution of inhibitory and excitatory synapses on hippocampal CA1 pyramidal cells. Neuroscience 102:527-40 [PubMed]

Mel BW (1992) The clusteron: toward a simple abstraction for a complex neuron Advances in Neural Information Processing Systems 11, Moody J:Hanson S:Lippmann R, ed. pp.35

Mel BW, Ruderman DL, Archie KA (1998) Translation-invariant orientation tuning in visual "complex" cells could derive from intradendritic computations. J Neurosci 18:4325-34 [PubMed]

Migliore M, Shepherd GM (2002) Emerging rules for the distributions of active dendritic conductances. Nature Review Neuroscience 3:362-70 [Journal] [PubMed]

   Modulation of temporal integration window (Migliore, Shepherd 2002) [Model]

Nettleton JS, Spain WJ (2000) Linear to supralinear summation of AMPA-mediated EPSPs in neocortical pyramidal neurons. J Neurophysiol 83:3310-22 [Journal] [PubMed]

Oakley JC, Schwindt PC, Crill WE (2001) Initiation and propagation of regenerative Ca(2+)-dependent potentials in dendrites of layer 5 pyramidal neurons. J Neurophysiol 86:503-13 [Journal] [PubMed]

Oviedo H, Reyes AD (2002) Boosting of neuronal firing evoked with asynchronous and synchronous inputs to the dendrite. Nat Neurosci 5:261-6 [PubMed]

Poirazi P, Brannon T, Mel BW (2003a) Arithmetic of subthreshold synaptic summation in a model CA1 pyramidal cell. Neuron 37:977-987 [Journal] [PubMed]

   CA1 pyramidal neuron: as a 2-layer NN and subthreshold synaptic summation (Poirazi et al 2003) [Model]

Poirazi P, Brannon T, Mel BW (2003b) Pyramidal Neuron as Two-Layer Neural Network. Neuron 37:989-999 [Journal] [PubMed]

   CA1 pyramidal neuron: as a 2-layer NN and subthreshold synaptic summation (Poirazi et al 2003) [Model]

Poirazi P, Mel BW (2001) Impact of active dendrites and structural plasticity on the memory capacity of neural tissue. Neuron 29:779-96 [PubMed]

Rall W, Segev I (1987) Functional possibilities for synapses on dendrites and on dendritic spines. Synaptic Function. Edelman G, Gall W, and Cowan W eds., Edelman GM:Gall WE:Cowan WM, ed. pp.605

Reyes A (2001) Influence of dendritic conductances on the input-output properties of neurons. Annu Rev Neurosci 24:653-75 [PubMed]

Rhodes PA (1999) Functional implications of active currents in the dendrites of pyramidal neurons Cerebral Cortex, Ulinksi PS:Jones EG:Peters A, ed. pp.1398

Schiller J, Major G, Koester HJ, Schiller Y (2000) NMDA spikes in basal dendrites of cortical pyramidal neurons. Nature 404:285-9 [PubMed]

Schiller J, Schiller Y (2001) NMDA receptor-mediated dendritic spikes and coincident signal amplification. Curr Opin Neurobiol 11:343-8 [PubMed]

Schiller J, Schiller Y, Stuart G, Sakmann B (1997) Calcium action potentials restricted to distal apical dendrites of rat neocortical pyramidal neurons. J Physiol 505 ( Pt 3):605-16 [PubMed]

Shepherd GM, Brayton RK (1987) Logic operations are properties of computer-simulated interactions between excitable dendritic spines. Neuroscience 21:151-65 [Journal] [PubMed]

Single S, Borst A (1998) Dendritic integration and its role in computing image velocity. Science 281:1848-50 [PubMed]

Tamas G, Szabadics J, Somogyi P (2002) Cell type- and subcellular position-dependent summation of unitary postsynaptic potentials in neocortical neurons. J Neurosci 22:740-7 [PubMed]

Urban NN, Barrionuevo G (1998) Active summation of excitatory postsynaptic potentials in hippocampal CA3 pyramidal neurons. Proc Natl Acad Sci U S A 95:11450-5 [PubMed]

Wei DS, Mei YA, Bagal A, Kao JP, Thompson SM, Tang CM (2001) Compartmentalized and binary behavior of terminal dendrites in hippocampal pyramidal neurons. Science 293:2272-5 [PubMed]

Williams SR, Stuart GJ (2002) Dependence of EPSP efficacy on synapse location in neocortical pyramidal neurons. Science 295:1907-10 [PubMed]

Almog M, Korngreen A (2014) A Quantitative Description of Dendritic Conductances and Its Application to Dendritic Excitation in Layer 5 Pyramidal Neurons J Neurosci 34(1):182-196 [Journal]

   Ionic mechanisms of dendritic spikes (Almog and Korngreen 2014) [Model]

Azouz R, Gray CM (2008) Stimulus-selective spiking is driven by the relative timing of synchronous excitation and disinhibition in cat striate neurons in vivo. Eur J Neurosci 28:1286-300 [PubMed]

Behabadi BF, Mel BW (2014) Mechanisms underlying subunit independence in pyramidal neuron dendrites. Proc Natl Acad Sci U S A 111:498-503 [Journal] [PubMed]

   Mechanisms underlying subunit independence in pyramidal neuron dendrites (Behabadi and Mel 2014) [Model]

Behabadi BF, Polsky A, Jadi M, Schiller J, Mel BW (2012) Location-dependent excitatory synaptic interactions in pyramidal neuron dendrites. PLoS Comput Biol 8:e1002599 [Journal] [PubMed]

   Excitatory synaptic interactions in pyramidal neuron dendrites (Behabadi et al. 2012) [Model]

Branco T, Hausser M (2011) Synaptic integration gradients in single cortical pyramidal cell dendrites. Neuron 69:885-92 [Journal] [PubMed]

   Dendritic Discrimination of Temporal Input Sequences (Branco et al. 2010) [Model]

Cazé RD, Jarvis S, Foust AJ, Schultz SR (2017) Dendrites Enable a Robust Mechanism for Neuronal Stimulus Selectivity. Neural Comput :1-17 [Journal] [PubMed]

   Dendrites enable a robust mechanism for neuronal stimulus selectivity (Caze et al 2017) [Model]

Das A, Narayanan R (2015) Active dendrites mediate stratified gamma-range coincidence detection in hippocampal model neurons. J Physiol [PubMed]

Djurisic M, Popovic M, Carnevale N, Zecevic D (2008) Functional Structure of the Mitral Cell Dendritic Tuft in the Rat Olfactory Bulb J. Neurosci. 28:4057-4068 [Journal] [PubMed]

   Functional structure of mitral cell dendritic tuft (Djurisic et al. 2008) [Model]

Doiron B, Oswald AM, Maler L (2007) Interval Coding. II. Dendrite-Dependent Mechanisms. J Neurophysiol 97:2744-57 [Journal] [PubMed]

Fernandez FR, Mehaffey WH, Turner RW (2005) Dendritic na+ current inactivation can increase cell excitability by delaying a somatic depolarizing afterpotential. J Neurophysiol 94:3836-48 [Journal] [PubMed]

   Dendritic Na inactivation drives a decrease in ISI (Fernandez et al 2005) [Model]

Gasparini S, Migliore M, Magee JC (2004) On the initiation and propagation of dendritic spikes in CA1 pyramidal neurons. J Neurosci 24:11046-11056 [Journal] [PubMed]

   CA1 pyramidal neuron: dendritic spike initiation (Gasparini et al 2004) [Model]

Gidon A, Segev I (2012) Principles governing the operation of synaptic inhibition in dendrites Neuron 75:330-41 [Journal] [PubMed]

   Principles governing the operation of synaptic inhibition in dendrites (Gidon & Segev 2012) [Model]

Grunditz A, Holbro N, Tian L, Zuo Y, Oertner TG (2008) Spine Neck Plasticity Controls Postsynaptic Calcium Signals through Electrical Compartmentalization J Neurosci 28(50):13457-13466 [Journal] [PubMed]

   Spine neck plasticity controls postsynaptic calcium signals (Grunditz et al. 2008) [Model]

Hao J, Wang XD, Dan Y, Poo MM, Zhang XH (2009) An arithmetic rule for spatial summation of excitatory and inhibitory inputs in pyramidal neurons. Proc Natl Acad Sci U S A 106:21906-11 [Journal] [PubMed]

   Spatial summation of excitatory and inhibitory inputs in pyramidal neurons (Hao et al. 2010) [Model]

Hawkins J, Ahmad S (2016) Why Neurons Have Thousands of Synapses, a Theory of Sequence Memory in Neocortex. Front Neural Circuits 10:23 [Journal] [PubMed]

   Theory of sequence memory in neocortex (Hawkins & Ahmad 2016) [Model]

Hay E, Hill S, Schurmann F, Markram H, Segev I (2011) Models of neocortical layer 5b pyramidal cells capturing a wide range of dendritic and perisomatic active properties. PLoS Comput Biol 7:e1002107 [Journal] [PubMed]

   Cortical Layer 5b pyr. cell with [Na+]i mechanisms, from Hay et al 2011 (Zylbertal et al 2017) [Model]
   L5b PC model constrained for BAC firing and perisomatic current step firing (Hay et al., 2011) [Model]

Hay E, Segev I (2015) Dendritic excitability and gain control in recurrent cortical microcircuits Cerebral Cortex 25(10):3561-3571 [Journal] [PubMed]

   Microcircuits of L5 thick tufted pyramidal cells (Hay & Segev 2015) [Model]

Hyun JH, Eom K, Lee KH, Bae JY, Bae YC, Kim MH, Kim S, Ho WK, Lee SH (2015) Kv1.2 mediates heterosynaptic modulation of direct cortical synaptic inputs in CA3 pyramidal cells. J Physiol 593:3617-43 [Journal] [PubMed]

   CA3 pyramidal neurons: Kv1.2 mediates modulation of cortical inputs (Hyun et al., 2015) [Model]

Iannella N, Tanaka S (2006) Synaptic efficacy cluster formation across the dendrite via STDP. Neurosci Lett 403:24-9 [Journal] [PubMed]

Jolivet R, Gerstner W (2006) Predicting spike times of a detailed conductance-based neuron model driven by stochastic spike arrival. J Physiol Paris 98:442-51 [PubMed]

Jolivet R, Rauch A, Luscher HR, Gerstner W (2006) Predicting spike timing of neocortical pyramidal neurons by simple threshold models. J Comput Neurosci 21:35-49 [PubMed]

Jovlivet R, Rauch A, Luscher HR, Gerstner W (2006) Predicting spike timing of neocortical pyramidal neurons by simple threshold models J Comput Neurosci 21:35-49 [Journal]

Kampa BM, Stuart GJ (2006) Calcium spikes in basal dendrites of layer 5 pyramidal neurons during action potential bursts. J Neurosci 26:7424-32 [Journal] [PubMed]

   Calcium spikes in basal dendrites (Kampa and Stuart 2006) [Model]

Katona G, Kaszas A, Turi GF, Hajos N, Tamas G, Vizi ES, Rozsa B (2011) Roller Coaster Scanning reveals spontaneous triggering of dendritic spikes in CA1 interneurons. Proc Natl Acad Sci U S A 108:2148-53 [Journal] [PubMed]

   CA1 stratum radiatum interneuron multicompartmental model (Katona et al. 2011) [Model]

Katz Y, Menon V, Nicholson DA, Geinisman Y, Kath WL, Spruston N (2009) Synapse distribution suggests a two-stage model of dendritic integration in CA1 pyramidal neurons. Neuron 63:171-7 [Journal] [PubMed]

   A two-stage model of dendritic integration in CA1 pyramidal neurons (Katz et al. 2009) [Model]

Keren N, Peled N, Korngreen A (2005) Constraining compartmental models using multiple voltage recordings and genetic algorithms. J Neurophysiol 94:3730-42 [Journal] [PubMed]

Larkum ME, Nevian T, Sandler M, Polsky A, Schiller J (2009) Synaptic integration in tuft dendrites of layer 5 pyramidal neurons: a new unifying principle. Science 325:756-60 [Journal] [PubMed]

   Synaptic integration in tuft dendrites of layer 5 pyramidal neurons (Larkum et al. 2009) [Model]

Lavzin M, Rapoport S, Polsky A, Garion L, Schiller J (2012) Nonlinear dendritic processing determines angular tuning of barrel cortex neurons in vivo. Nature 490:397-401 [Journal] [PubMed]

   Nonlinear dendritic processing in barrel cortex spiny stellate neurons (Lavzin et al. 2012) [Model]

Le Franc Y, Le Masson G (2010) Multiple firing patterns in deep Dorsal Horn Neurons of the spinal cord: computational analysis of mechanisms and functional implications. J Neurophysiol [Journal] [PubMed]

Li X, Ascoli GA (2008) Effects of synaptic synchrony on the neuronal input-output relationship. Neural Comput 20:1717-31 [PubMed]

   CA1 pyramidal neuron synaptic integration (Li and Ascoli 2006, 2008) [Model]

Lytton WW, Neymotin SA, Wester JC, Contreras D (2011) Neocortical simulation for epilepsy surgery guidance: Localization and intervention Computational Surgery and Dual Training

   Computational Surgery (Lytton et al. 2011) [Model]

Major G, Polsky A, Denk W, Schiller J, Tank DW (2008) Spatiotemporally graded NMDA spike-plateau potentials in basal dendrites of neocortical pyramidal neurons. J Neurophysiol 99:2584-601 [PubMed]

Menon V, Musial TF, Liu A, Katz Y, Kath WL, Spruston N, Nicholson DA (2013) Balanced synaptic impact via distance-dependent synapse distribution and complementary expression of AMPARs and NMDARs in hippocampal dendrites. Neuron 80:1451-63 [Journal] [PubMed]

   Distance-dependent synaptic strength in CA1 pyramidal neurons (Menon et al. 2013) [Model]

Migliore M, Ferrante M, Ascoli GA (2005) Signal propagation in oblique dendrites of CA1 pyramidal cells. J Neurophysiol 94:4145-4155 [Journal] [PubMed]

   CA1 pyramidal neuron: signal propagation in oblique dendrites (Migliore et al 2005) [Model]

Miller JA, Kenyon GT (2007) Extracting number-selective responses from coherent oscillations in a computer model. Neural Comput 19:1766-97 [PubMed]

Morita K (2008) Possible role of dendritic compartmentalization in the spatial working memory circuit. J Neurosci 28:7699-724 [Journal] [PubMed]

   Working memory circuit with branched dendrites (Morita 2008) [Model]

Nevian T, Larkum ME, Polsky A, Schiller J (2007) Properties of basal dendrites of layer 5 pyramidal neurons: a direct patch-clamp recording study. Nat Neurosci 10:206-14 [Journal] [PubMed]

   Dendritic Na+ spike initiation and backpropagation of APs in active dendrites (Nevian et al. 2007) [Model]

Olshausen BA, Field DJ (2005) How close are we to understanding v1? Neural Comput 17:1665-99

Poleg-Polsky A (2015) Effects of Neural Morphology and Input Distribution on Synaptic Processing by Global and Focal NMDA-spikes PLOS One 10(10):e0140254 [Journal] [PubMed]

   Effects of neural morphology on global and focal NMDA-spikes (Poleg-Polsky 2015) [Model]

Poleg-Polsky A, Diamond JS (2016) NMDA Receptors Multiplicatively Scale Visual Signals and Enhance Directional Motion Discrimination in Retinal Ganglion Cells. Neuron 89:1277-90 [Journal] [PubMed]

   Multiplication by NMDA receptors in Direction Selective Ganglion cells (Poleg-Polsky & Diamond 2016) [Model]

Polsky A, Mel B, Schiller J (2009) Encoding and decoding bursts by NMDA spikes in basal dendrites of layer 5 pyramidal neurons. J Neurosci 29:11891-903 [Journal] [PubMed]

   NMDA spikes in basal dendrites of L5 pyramidal neurons (Polsky et al. 2009) [Model]

Rabinowitch I, Segev I (2006a) The endurance and selectivity of spatial patterns of long-term potentiation-depression in dendrites under homeostatic synaptic plasticity. J Neurosci 26:13474-84 [Journal] [PubMed]

   Homeostatic synaptic plasticity (Rabinowitch and Segev 2006a,b) [Model]

Rabinowitch I, Segev I (2006b) The interplay between homeostatic synaptic plasticity and functional dendritic compartments. J Neurophysiol 96:276-83 [Journal] [PubMed]

   Homeostatic synaptic plasticity (Rabinowitch and Segev 2006a,b) [Model]

Rabinowitch I, Segev I (2008) Two opposing plasticity mechanisms pulling a single synapse. Trends Neurosci [Journal] [PubMed]

   Homeostatic synaptic plasticity (Rabinowitch and Segev 2006a,b) [Model]

Rhodes P (2006) The properties and implications of NMDA spikes in neocortical pyramidal cells. J Neurosci 26:6704-15 [PubMed]

Shu Y, Duque A, Yu Y, Haider B, McCormick DA (2007) Properties of action-potential initiation in neocortical pyramidal cells: evidence from whole cell axon recordings. J Neurophysiol 97:746-60 [Journal] [PubMed]

   Intracortical synaptic potential modulation by presynaptic somatic potential (Shu et al. 2006, 2007) [Model]

Takashima A, Hikosaka R, Takahata M (2006) Functional Significance of Passive and Active Dendritic Properties in the Synaptic Integration by an Identified Nonspiking Interneuron of Crayfish. J Neurophysiol 96(6):3157-69 [Journal] [PubMed]

   Synaptic integration of an identified nonspiking interneuron in crayfish (Takashima et al 2006) [Model]

Tamosiunaite M, Porr B, Worgotter F (2007) Self-influencing synaptic plasticity: Recurrent changes of synaptic weights can lead to specific functional properties. J Comput Neurosci 23:113-127 [Journal] [PubMed]

   Self-influencing synaptic plasticity (Tamosiunaite et al. 2007) [Model]

Timofeeva Y, Lord GJ, Coombes S (2006) Spatio-temporal filtering properties of a dendritic cable with active spines: a modeling study in the spike-diffuse-spike framework. J Comput Neurosci 21:293-306 [Journal] [PubMed]

Urban NN, Castro JB (2005) Tuft Calcium Spikes in Accessory Olfactory Bulb Mitral Cells J Neurosci 25(50):5024-5028

Wang XD, Hao J, Poo MM, Zhang XH (2006) How does a neuron perform subtraction? - Arithmetic rules of synaptic integration of excitation and inhibition Advances in Neural Networks-ISNN 2006 3971:7-14

(95 refs)