Citation Relationships



Silva J, Rudy Y (2005) Subunit interaction determines IKs participation in cardiac repolarization and repolarization reserve. Circulation 112:1384-91 [PubMed]

   Role of KCNQ1 and IKs in cardiac repolarization (Silva, Rudy 2005)

   Role of KCNQ1 and IKs in cardiac repolarization (Silva, Rudy 2005) (XPP)

References and models cited by this paper

References and models that cite this paper

Antzelevitch C, Dumaine R (2002) Electrical heterogeneity in the heart: physiological, pharmacological and clinical implications. Handbook of Physiology, Section 2: The Cardiovascular System, Page E:Fozzard H:Solaro J, ed. pp.654

Clay JR (1995) A simple model of K+ channel activation in nerve membrane. J Theor Biol 175:257-62 [Journal] [PubMed]

Cui J, Kline RP, Pennefather P, Cohen IS (1994) Gating of IsK expressed in Xenopus oocytes depends on the amount of mRNA injected. J Gen Physiol 104:87-105 [PubMed]

Hund TJ, Rudy Y (2004) Rate dependence and regulation of action potential and calcium transient in a canine cardiac ventricular cell model. Circulation 110:3168-74 [Journal] [PubMed]

   A dynamic model of the canine ventricular myocyte (Hund, Rudy 2004) [Model]

Koren G, Liman ER, Logothetis DE, Nadal-Ginard B, Hess P (1990) Gating mechanism of a cloned potassium channel expressed in frog oocytes and mammalian cells. Neuron 4:39-51 [PubMed]

Kupershmidt S, Yang IC, Sutherland M, Wells KS, Yang T, Yang P, Balser JR, Roden DM (2002) Cardiac-enriched LIM domain protein fhl2 is required to generate I(Ks) in a heterologous system. Cardiovasc Res 56:93-103 [PubMed]

Lu Z, Kamiya K, Opthof T, Yasui K, Kodama I (2001) Density and kinetics of I(Kr) and I(Ks) in guinea pig and rabbit ventricular myocytes explain different efficacy of I(Ks) blockade at high heart rate in guinea pig and rabbit: implications for arrhythmogenesis in humans. Circulation 104:951-6 [PubMed]

Marx SO, Kurokawa J, Reiken S, Motoike H, D'Armiento J, Marks AR, Kass RS (2002) Requirement of a macromolecular signaling complex for beta adrenergic receptor modulation of the KCNQ1-KCNE1 potassium channel. Science 295:496-9 [Journal] [PubMed]

Rocchetti M, Besana A, Gurrola GB, Possani LD, Zaza A (2001) Rate dependency of delayed rectifier currents during the guinea-pig ventricular action potential. J Physiol 534:721-32 [PubMed]

Roden DM (2004) Drug-induced prolongation of the QT interval. N Engl J Med 350:1013-22 [Journal] [PubMed]

Sanguinetti MC, Curran ME, Zou A, Shen J, Spector PS, Atkinson DL, Keating MT (1996) Coassembly of K(V)LQT1 and minK (IsK) proteins to form cardiac I(Ks) potassium channel. Nature 384:80-3 [Journal] [PubMed]

Saucerman JJ, Brunton LL, Michailova AP, McCulloch AD (2003) Modeling beta-adrenergic control of cardiac myocyte contractility in silico. J Biol Chem 278:47997-8003 [Journal] [PubMed]

Sicouri S, Quist M, Antzelevitch C (1996) Evidence for the presence of M cells in the guinea pig ventricle. J Cardiovasc Electrophysiol 7:503-11 [PubMed]

Splawski I, Tristani-Firouzi M, Lehmann MH, Sanguinetti MC, Keating MT (1997) Mutations in the hminK gene cause long QT syndrome and suppress IKs function. Nat Genet 17:338-40 [Journal] [PubMed]

Stengl M, Volders PG, Thomsen MB, Spätjens RL, Sipido KR, Vos MA (2003) Accumulation of slowly activating delayed rectifier potassium current (IKs) in canine ventricular myocytes. J Physiol 551:777-86 [Journal] [PubMed]

Tristani-Firouzi M, Sanguinetti MC (1998) Voltage-dependent inactivation of the human K+ channel KvLQT1 is eliminated by association with minimal K+ channel (minK) subunits. J Physiol 510 ( Pt 1):37-45 [PubMed]

Virág L, Iost N, Opincariu M, Szolnoky J, Szécsi J, Bogáts G, Szenohradszky P, Varró A, Papp JG (2001) The slow component of the delayed rectifier potassium current in undiseased human ventricular myocytes. Cardiovasc Res 49:790-7 [PubMed]

Viswanathan PC, Shaw RM, Rudy Y (1999) Effects of IKr and IKs heterogeneity on action potential duration and its rate dependence: a simulation study. Circulation 99:2466-74 [PubMed]

   Ventricular cell model (Guinea-pig-type) (Luo, Rudy 1991, +11 other papers!) (C++) [Model]

Volders PG, Stengl M, van Opstal JM, Gerlach U, Spätjens RL, Beekman JD, Sipido KR, Vos MA (2003) Probing the contribution of IKs to canine ventricular repolarization: key role for beta-adrenergic receptor stimulation. Circulation 107:2753-60 [Journal] [PubMed]

Zagotta WN, Hoshi T, Aldrich RW (1994) Shaker potassium channel gating. III: Evaluation of kinetic models for activation. J Gen Physiol 103:321-62 [PubMed]

Zagotta WN, Hoshi T, Dittman J, Aldrich RW (1994) Shaker potassium channel gating. II: Transitions in the activation pathway. J Gen Physiol 103:279-319 [PubMed]

Zeng J, Rudy Y (1995) Early afterdepolarizations in cardiac myocytes: mechanism and rate dependence. Biophys J 68:949-64 [Journal] [PubMed]

   Ventricular cell model (Guinea-pig-type) (Luo, Rudy 1991, +11 other papers!) (C++) [Model]

Severi S, Corsi C, Rocchetti M, Zaza A (2009) Mechanisms of beta-adrenergic modulation of I(Ks) in the guinea-pig ventricle: insights from experimental and model-based analysis. Biophys J 96:3862-72 [Journal] [PubMed]

   A model of beta-adrenergic modulation of IKs in the guinea-pig ventricle (Severi et al. 2009) [Model]

Sung RJ, Wu SN, Wu JS, Chang HD, Luo CH (2006) Electrophysiological mechanisms of ventricular arrhythmias in relation to Andersen-Tawil syndrome under conditions of reduced IK1: a simulation study. Am J Physiol Heart Circ Physiol 291:H2597-605 [Journal] [PubMed]

   Simulation study of Andersen-Tawil syndrome (Sung et al 2006) [Model]

Wang YJ, Sung RJ, Lin MW, Wu SN (2006) Contribution of BK(Ca)-channel activity in human cardiac fibroblasts to electrical coupling of cardiomyocytes-fibroblasts. J Membr Biol 213:175-85 [Journal] [PubMed]

   Ventricular cell model (Luo Rudy dynamic model) (Luo Rudy 1994) used in (Wang et al 2006) (XPP) [Model]
   Ventricular cell model (Guinea-pig-type) (Luo, Rudy 1991, +11 other papers!) (C++) [Model]

(25 refs)